Degeneration of the lumbar spine and dual-energy X-ray absorptiometry measurements in patients without osteoporosis

2009 ◽  
Vol 33 (5) ◽  
pp. 374-378 ◽  
Author(s):  
Ayce Atalay ◽  
Meral Kozakcioglu ◽  
Rahmi Cubuk ◽  
Nuri Tasali ◽  
Sefik Guney
Keyword(s):  
2021 ◽  
Vol 80 (Suppl 1) ◽  
pp. 227.2-228
Author(s):  
D. Claire ◽  
M. Geoffroy ◽  
L. Kanagaratnam ◽  
C. Isabelle ◽  
A. Hittinger ◽  
...  

Background:Dual energy X-ray absoprtiometry is the reference method to mesure bone mineral density (1). Loss of bone mineral density is significant if it exceeds the least significant change. The threshold value used in general population is 0,03 g/cm2 (2). Patients with obesity are known for having a higher bone mineral density due to metabolism and physiopathology characteristics (3,4).Objectives:The aim of our study was to determine the least significant change in bone densitometry in patients with obesity.Methods:We conducted an interventionnal study in 120 patients with obesity who performed a bone densitometry. We measured twice the bone mineral density at the lumbar spine, the femoral neck and the total hip in the same time (5,6). We determined the least significant change in bone densitometry from each pair of measurements, using the Bland and Altman method. We also determined the least significant change in bone densitometry according to each stage of obesity.Results:The least significant change in bone densitometry in patients with obesity is 0,046g/cm2 at the lumbar spine, 0.069 g/cm2 at the femoral neck and 0.06 g/cm2 at the total hip.Conclusion:The least significant change in bone densitometry in patients with obesity is higher than in general population. These results may improve DXA interpretation in this specific population, and may personnalize their medical care.References:[1]Lees B, Stevenson JC. An evaluation of dual-energy X-ray absorptiometry and comparison with dual-photon absorptiometry. Osteoporos Int. mai 1992;2(3):146-52.[2]Briot K, Roux C, Thomas T, Blain H, Buchon D, Chapurlat R, et al. Actualisation 2018 des recommandations françaises du traitement de l’ostéoporose post-ménopausique. Rev Rhum. oct 2018;85(5):428-40.[3]Shapses SA, Pop LC, Wang Y. Obesity is a concern for bone health with aging. Nutr Res N Y N. mars 2017;39:1-13.[4]Savvidis C, Tournis S, Dede AD. Obesity and bone metabolism. Hormones. juin 2018;17(2):205-17.[5]Roux C, Garnero P, Thomas T, Sabatier J-P, Orcel P, Audran M, et al. Recommendations for monitoring antiresorptive therapies in postmenopausal osteoporosis. Jt Bone Spine Rev Rhum. janv 2005;72(1):26-31.[6]Ravaud P, Reny JL, Giraudeau B, Porcher R, Dougados M, Roux C. Individual smallest detectable difference in bone mineral density measurements. J Bone Miner Res. août 1999;14(8):1449-56.Disclosure of Interests:None declared.


Author(s):  
Carla Caffarelli ◽  
Maria Dea Tomai Pitinca ◽  
Antonella Al Refaie ◽  
Elena Ceccarelli ◽  
Stefano Gonnelli

Abstract Background Patients with type 2 diabetes (T2DM) have an increased or normal BMD; however fragility fractures represent one of the most important complications of T2DM. Aims This study aimed to evaluate whether the use of the Radiofrequency Echographic multi spectrometry (REMS) technique may improve the identification of osteoporosis in T2DM patients. Methods In a cohort of 90 consecutive postmenopausal elderly (70.5 ± 7.6 years) women with T2DM and in 90 healthy controls we measured BMD at the lumbar spine (LS-BMD), at femoral neck (FN-BMD) and total hip (TH-BMD) using a dual-energy X-ray absorptiometry device; moreover, REMS scans were also carried out at the same axial sites. Results DXA measurements were all higher in T2DM than in non-T2DM women; instead, all REMS measurements were lower in T2DM than in non T2DM women. Moreover, the percentage of T2DM women classified as “osteoporotic”, on the basis of BMD by REMS was markedly higher with respect to those classified by DXA (47.0% vs 28.0%, respectively). On the contrary, the percentage of T2DM women classified as osteopenic or normal by DXA was higher with respect to that by REMS (48.8% and 23.2% vs 38.6% and 14.5%, respectively). T2DM women with fragility fractures presented lower values of both BMD-LS by DXA and BMD-LS by REMS with respect to those without fractures; however, the difference was significant only for BMD-LS by REMS (p < 0.05). Conclusions Our data suggest that REMS technology may represent a useful approach to enhance the diagnosis of osteoporosis in patients with T2DM.


1995 ◽  
Vol 5 (3) ◽  
pp. 196-204 ◽  
Author(s):  
M. Jergas ◽  
M. Breitenseher ◽  
C. -C. Glüer ◽  
D. Black ◽  
P. Lang ◽  
...  
Keyword(s):  

Neurosurgery ◽  
2019 ◽  
Vol 66 (Supplement_1) ◽  
Author(s):  
Awais Vance ◽  
Alexander Mazal ◽  
Salah G Aoun ◽  
Najib El Tecle ◽  
Matthew Thomas Davies ◽  
...  

Abstract INTRODUCTION Diminished bone mineral density (BMD) places patients at increased risk for complications from lumbar fusion procedures. Dual-energy X-Ray absorptiometry (DEXA) scanners have been used as the gold standard in measuring BMD. More recently, various studies have suggested that Hounsfield unit measurements from computed tomography (CT) scans may be more accurate. METHODS After obtaining IRB approval, we retrospectively reviewed all patients aged 18 and older who underwent lumbar fusion procedures between 01/01/2010 and 12/31/2016 at our institution. We used linear regression to assess for a correlation between CT Hounsfield units and DEXA t scores. Student's t-test was used to compare CT Hounsfield units, lumbar spine t score and hip t scores for patients with and without pseudoarthrosis as well as those with and without hardware failure. RESULTS A total of 167 patients with lumbar fusion procedures met inclusion criteria. Ages ranged 24 to 88 yr old with a mean of 64. Using linear regression there was no correlation between CT Hounsfield units and Dexa T scores. There was no difference between the groups with respect to CT Hounsfield units or DEXA T scores when comparing patients with and without pseudoarthrosis and when comparing patients with or without hardware failure. CONCLUSION Diminished BMD is an important factor to consider when contemplating lumbar spine fusion procedures as this has been associated with increased risk of hardware failure or pseudoarthrosis. Traditionally DEXA scans and more recently CT Hounsfield units have used to screen patients for decreased BMD, however, in this relatively large retrospective series we found that neither correlate well with complications from lumbar spine fusion procedures. CT and DEXA scans may not be as reliable as once thought in assessing BMD.


1992 ◽  
Vol 22 (8) ◽  
pp. 560-562 ◽  
Author(s):  
H. Tsukahara ◽  
M. Sudo ◽  
M. Umezaki ◽  
M. Hiraoka ◽  
K. Yamamoto ◽  
...  

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