Early Diagnosis and Treatment of Cerebral Palsy in Children with a History of Preterm Birth

Recently an increase in the incidence of mucormycosis is noticed in COVID-19 cases. The main aim of this study is to present our experience of rhino-orbito-cerebral mucormycosis in COVID-19 patients and thereby aid its early diagnosis and treatment. This is a prospective study of 12 cases diagnosed as Rhino-orbito-cerebral mucormycosis . Presentation of mucormycosis in COVID-19, their temporal association and outcome of treatment was studied. Pre-existing comorbidities were seen in 91.67% patients, Diabetes Mellitus (83.33%). Previous history of COVID-19 infection and treatment for the same in 41.67% cases, concomitant infection in 16.67% and asymptomatic undiagnosed covid (antibodies positive) was detected in 41.67%. All patients showed improvement in general and nasal condition (100%). Early diagnosis is must.

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Advanced metastatic breast carcinoma in sickle cell disease

Zinc supplementation improves heme biosynthesis in rats exposed to lead ◽

10.18051/univmed.2019.v38.139-143 ◽

2019 ◽

Vol 38 (2) ◽

pp. 139

Author(s):

Marcellinus Uchechukwu Nwagu ◽

Ologo Thompson ◽

Akinola Oyekemi

Keyword(s):

Breast Cancer ◽

Family History ◽

Sickle Cell Disease ◽

Early Diagnosis ◽

Sickle Cell ◽

Positive Family History ◽

Metastatic Breast ◽

Diagnosis And Treatment ◽

Cell Disease ◽

History Of

Background Breast cancer is the leading cancer in women leading to over 400,000 deaths per year worldwide. It begins in the breast tissue and can metastasize to other organs if early diagnosis and treatment is not instituted. Women with sickle cell disease are usually spared from breast cancer and other solid tumours due to the tumoricidal effect of sickled erythrocytes. Breast cancers are rare among these group of patients. Despite its rare occurrence, this paper was to emphasize the need for breast cancer screening among female sickle cell disease patients who have positive family history of breast cancer. Case description OO was a 30-year old woman with sickle cell disease who presented to the hospital one and half years ago with a seven months history of right breast swelling and pains. She had lost her mother to breast cancer about 15 years ago. Mammography and histology of breast biopsy confirmed diagnosis of invasive ductal carcinoma of the right breast. Financial constraint was a major challenge in managing this patient as she was unable to buy her chemotherapy. She developed features suggestive of metastasis such as seizures and hepatomegaly. She was stabilized and discharged home but we lost her to follow up. She died at home. Conclusion Breast cancer is rare among females with sickle cell disease; any of them with a family history should be routinely screened for early diagnosis and treatment.

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Submucous Cleft Palates Presenting with a Perforation

The Cleft Palate-Craniofacial Journal ◽

10.1597/1545-1569_2003_040_0203_scppwa_2.0.co_2 ◽

2003 ◽

Vol 40 (2) ◽

pp. 203-206 ◽

Cited By ~ 6

Author(s):

Felicity V. Mehendale ◽

Brian C. Sommerlad

Keyword(s):

Surgical Treatment ◽

Early Diagnosis ◽

Cleft Palate ◽

Diagnosis And Treatment ◽

Minor Trauma ◽

Rare Occurrence ◽

Submucous Cleft Palate ◽

History Of ◽

Symptoms And Signs

Objective The development of a perforation in a submucous cleft palate (SMCP) is a rare occurrence, with only a few cases reported in the literature. We describe and illustrate four cases of SMCPs with a perforation in the palate. Results and Conclusions Recognition of the symptoms and signs of an SMCP should enable early diagnosis and treatment of this condition in symptomatic patients. However, in patients in whom the diagnosis has been missed or in those who have been asymptomatic, the development of a perforation may be the presenting feature of an SMCP. A history of possible trauma to the palate was found in two cases. Relatively minor trauma may cause perforation of the thin translucent central mucosa in an SMCP. In neonates, perforations surrounded by very thin mucosa may increase in size. The perforation can be closed at the same time as the SMCP repair and does not significantly alter the surgical treatment of an SMCP.

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Tibia vara or Blount’s disease: Why an early diagnosis and treatment are important?

Clinics and Practice ◽

10.4081/cp.2020.1222 ◽

2020 ◽

Vol 10 (1) ◽

Author(s):

Angelo V. Vasiliadis ◽

Alexandros Maris ◽

Srinivas Gadikoppula

Keyword(s):

Early Diagnosis ◽

Health Outcomes ◽

Proximal Tibia ◽

Three Dimensional ◽

Good Health ◽

Diagnosis And Treatment ◽

Tibia Vara ◽

Blount’S Disease ◽

History Of ◽

Anterior Knee

Tibia vara is an asymmetrical disorder of the proximal tibia that produces a three-dimensional deformity, which was first described by Blount in 1937. A 6-year-old boy presented with a history of anterior knee pain with progressive bowing of his right leg over the last 1 year after having a fall while playing soccer. An early diagnosis and treatment of this disease can have a great functional impact and lead to very good health outcomes.

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Early Diagnosis and Treatment of Pancreatic Dysplasia in Patients with a Family History of Pancreatic Cancer

Annals of Internal Medicine ◽

10.7326/0003-4819-131-4-199908170-00003 ◽

1999 ◽

Vol 131 (4) ◽

pp. 247 ◽

Cited By ~ 264

Author(s):

Teresa A. Brentnall ◽

Mary P. Bronner ◽

David R. Byrd ◽

Rodger C. Haggitt ◽

Michael B. Kimmey

Keyword(s):

Pancreatic Cancer ◽

Family History ◽

Early Diagnosis ◽

Diagnosis And Treatment ◽

History Of

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Variations of physiological parameters in newly detected hypothyroidism

International Journal of Research in Medical Sciences ◽

10.18203/2320-6012.ijrms20195539 ◽

2019 ◽

Vol 7 (12) ◽

pp. 4686

Author(s):

Seethalakshmi K. ◽

Biju Bahuleyan ◽

Sunil K. Menon

Keyword(s):

Blood Pressure ◽

Early Diagnosis ◽

Pulse Rate ◽

Cross Sectional Study ◽

Physiological Parameters ◽

Diagnosis And Treatment ◽

Respiratory Morbidity ◽

Public Health Issue ◽

Cross Sectional ◽

History Of

Background: Emergence of hypothyroidism as a public health issue apart from a common clinical entity, has gained much attention nowadays. The non-specific features of hypothyroidism lead to incorrect diagnoses, inadequate treatment and complications in the future. The present study was designed to unravel the effects of hypothyroidism on physiological parameters and to highlight the importance of early diagnosis and treatment. This study was done to assess the effects of hypothyroidism on pulse rate, blood pressure and respiratory rate.Methods: This descriptive cross-sectional study was done in 60 hypothyroid patients of 18-45 years age, both males and females, who were either newly detected or on treatment for less than 6 months. Patients with history of other systemic diseases, pregnancy and hyperthyroidism were excluded. After obtaining written consent from the patients, clinical examination was done.Results: Student t-test and ANOVA were used for analysis. Physiological parameters like pulse rate, blood pressure and respiratory rate had variations in the patients and there were changes with age, gender and BMI even though they were not significant. These changes were attributed to increased arterial wall thickness and endothelial dysfunction in blood vessels.Conclusions: The patients showed changes in cardiovascular and respiratory profiles. The variations in systolic and diastolic blood pressures were significant with increase in age. Physiological parameters had variations with gender and BMI also. This proves the cardiovascular and respiratory morbidity in newly detected hypothyroidism, which emphasizes the importance of early diagnosis and treatment in them.

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Atypical Presentation of Thyroid Ophthalmopathy A Case Report

Medicine Today ◽

10.3329/medtoday.v25i1.16073 ◽

2013 ◽

Vol 25 (1) ◽

pp. 49-51

Author(s):

SMG Rabhani ◽

MA Rashid ◽

R Akhter ◽

M Hossain

Keyword(s):

Case Report ◽

Early Diagnosis ◽

Diagnosis And Treatment ◽

Atypical Presentation ◽

Neck Swelling ◽

Treatment Needs ◽

History Of ◽

Medicine Today ◽

One Year ◽

Thyroid Ophthalmopathy

This is a case report of atypical pesentation of thyroid ophthalmopathy. The case report presents a patient aged 32 years with the history of oligomenorrhoea for three years , dryness and grittiness of both eye for last one year and neck swelling for six month. She was diagnosed as thyroid ophthalmopathy. The case was treated with carbimazole and improved. Early diagnosis and treatment needs for better outcome. DOI: http://dx.doi.org/10.3329/medtoday.v25i1.16073 Medicine Today 2013 Vol.25(1): 49-51

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