The challenges of hydrodynamic forces on cells used in Cell Manufacturing and Therapy

Author(s):  
Jeffrey J. Chalmers
1995 ◽  
Vol 32 (2) ◽  
pp. 77-83
Author(s):  
Y. Yüksel ◽  
D. Maktav ◽  
S. Kapdasli

Submarine pipelines must be designed to resist wave and current induced hydrodynamic forces especially in and near the surf zone. They are buried as protection against forces in the surf zone, however this procedure is not always feasible particularly on a movable sea bed. For this reason the characteristics of the sediment transport on the construction site of beaches should be investigated. In this investigation, the application of the remote sensing method is introduced in order to determine and observe the coastal morphology, so that submarine pipelines may be protected against undesirable seabed movement.


2011 ◽  
Vol 1 (2) ◽  
pp. 173-181
Author(s):  
Laurence Guyonneau-Harmand ◽  
Luc Douay

Processes ◽  
2021 ◽  
Vol 9 (3) ◽  
pp. 452
Author(s):  
Yiyang Wang ◽  
Panagiotis Dimitrakopoulos

The lateral migration of elastic capsules towards a microchannel centerline plays a major role in industrial and physiological processes. Via our computational investigation, we show that a constriction connecting two straight microchannels facilitates the lateral capsule migration considerably, which is relatively slow in straight channels. Our work reveals that the significant cross-streamline migration inside the constriction is dominated by the strong hydrodynamic forces due to the capsule size. However, in the downstream straight channel, the increased interfacial deformation at higher capillary numbers or a lower viscosity ratio and lower membrane hardness results in increased lateral cross-streamline migration. Thus, our work highlights the different migration mechanisms occurring over curved and straight streamlines.


Author(s):  
Hassan F Ahmed ◽  
Hamayun Farooq ◽  
Imran Akhtar ◽  
Zafar Bangash

In this article, we introduce a machine learning–based reduced-order modeling (ML-ROM) framework through the integration of proper orthogonal decomposition (POD) and deep neural networks (DNNs), in addition to long short-term memory (LSTM) networks. The DNN is utilized to upscale POD temporal coefficients and their respective spatial modes to account for the dynamics represented by the truncated modes. In the second part of the algorithm, temporal evolution of the POD coefficients is obtained by recursively predicting their future states using an LSTM network. The proposed model (ML-ROM) is tested for flow past a circular cylinder characterized by the Navier–Stokes equations. We perform pressure mode decomposition analysis on the flow data using both POD and ML-ROM to predict hydrodynamic forces and demonstrate the accuracy of the proposed strategy for modeling lift and drag coefficients.


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