scholarly journals Facile construction of fluorescent traceable prodrug nanosponges for tumor intracellular pH/hypoxia dual-triggered drug delivery

2022 ◽  
Vol 46 ◽  
pp. 100576
Author(s):  
Wei Chen ◽  
Pengwei Xie ◽  
Mingliang Pei ◽  
Guoping Li ◽  
Zhiyuan Wang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Intracellular Ph

Intracellular pH-Sensitive PEG-block-Acetalated-Dextrans as Efficient Drug Delivery Platforms

2013 ◽  
Vol 5 (21) ◽  
pp. 10760-10766 ◽  
Author(s):  
Zhe Zhang ◽  
Xiaofei Chen ◽  
Li Chen ◽  
Shuangjiang Yu ◽  
Yue Cao ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Intracellular Ph ◽  
Ph Sensitive

A pH-responsive amphiphilic chitosan–pyranine core–shell nanoparticle for controlled drug delivery, imaging and intracellular pH measurement

2014 ◽  
Vol 2 (38) ◽  
pp. 6580-6589 ◽  
Author(s):  
Hao-Syun Chou ◽  
Meng-Hsuan Hsiao ◽  
Wei-Yang Hung ◽  
Tin-Yo Yen ◽  
Hui-Yi Lin ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Intracellular Ph ◽  
Controlled Drug Delivery ◽  
Ph Measurement ◽  
Core Shell ◽  
Ph Responsive ◽  
Cellular Resolution ◽  
New Type

A new type of CHC–PY core–shell nanoparticle provides multiple functionality, where a synergistic performance of nanotherapeutics, imaging and even diagnosis at a cellular resolution can be achieved simultaneously.

Improved in vivo tumor therapy via host–guest complexation

2016 ◽  
Vol 4 (15) ◽  
pp. 2691-2696 ◽  
Author(s):  
Yong Yao ◽  
Yang Wang ◽  
Ruibo Zhao ◽  
Li Shao ◽  
Ruikang Tang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Intracellular Ph ◽  
Tumor Therapy ◽  
Controlled Drug Delivery ◽  
Water Soluble ◽  
Ph Responsive ◽  
Mesoporous Nanoparticles

A decomposable and intracellular pH-responsive drug delivery system by immobilizing a water-soluble pillar[5]arene onto hollow mesoporous nanoparticles through host–guest complexation was successfully prepared and its application in controlled drug delivery in vitro and in vivo was also investigated.

Intracellular pH-activated PEG-b-PDPA wormlike micelles for hydrophobic drug delivery

2013 ◽  
Vol 4 (19) ◽  
pp. 5052 ◽  
Author(s):  
Haijun Yu ◽  
Zhiai Xu ◽  
Dangge Wang ◽  
Xianzhi Chen ◽  
Zhiwen Zhang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Intracellular Ph ◽  
Wormlike Micelles ◽  
Hydrophobic Drug

Intracellular pH-Sensitive Metallo-Supramolecular Nanogels for Anticancer Drug Delivery

2014 ◽  
Vol 6 (10) ◽  
pp. 7816-7822 ◽  
Author(s):  
Xuemei Yao ◽  
Li Chen ◽  
Xiaofei Chen ◽  
Zhe Zhang ◽  
Hui Zheng ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Intracellular Ph ◽  
Anticancer Drug ◽  
Ph Sensitive ◽  
Anticancer Drug Delivery

Complex Assembly of Polymer Conjugated Mesoporous Silica Nanoparticles for Intracellular pH-Responsive Drug Delivery

Langmuir ◽  
2016 ◽  
Vol 32 (47) ◽  
pp. 12453-12460 ◽  
Author(s):  
Yang Yang ◽  
Katharina Achazi ◽  
Yi Jia ◽  
Qiang Wei ◽  
Rainer Haag ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Intracellular Ph ◽  
Mesoporous Silica Nanoparticles ◽  
Ph Responsive ◽  
Complex Assembly

POSS-based supramolecular amphiphilic zwitterionic complexes for drug delivery

2019 ◽  
Vol 7 (5) ◽  
pp. 1984-1994 ◽  
Author(s):  
Linfeng Fan ◽  
Xing Wang ◽  
Qingchen Cao ◽  
Yanyu Yang ◽  
Decheng Wu
Keyword(s):  
Drug Delivery ◽  
Intracellular Ph ◽  
Biomedical Applications ◽  
Antitumor Drug ◽  
Antitumor Efficacy ◽  
Zwitterionic Polymer ◽  
Smart Drug ◽  
Zwitterionic Complexes ◽  
Smart Drug Delivery ◽  
Excellent Stability

A novel POSS-based supramolecular amphiphilic zwitterionic polymer exhibited excellent stability in both extracellular and intracellular pH environments and well encapsulated the antitumor drug DOX, and has the potential to improve smart drug delivery and enhance antitumor efficacy for biomedical applications.

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