POSS-based supramolecular amphiphilic zwitterionic complexes for drug delivery

2019 ◽  
Vol 7 (5) ◽  
pp. 1984-1994 ◽  
Author(s):  
Linfeng Fan ◽  
Xing Wang ◽  
Qingchen Cao ◽  
Yanyu Yang ◽  
Decheng Wu
Keyword(s):  
Drug Delivery ◽  
Intracellular Ph ◽  
Biomedical Applications ◽  
Antitumor Drug ◽  
Antitumor Efficacy ◽  
Zwitterionic Polymer ◽  
Smart Drug ◽  
Zwitterionic Complexes ◽  
Smart Drug Delivery ◽  
Excellent Stability

A novel POSS-based supramolecular amphiphilic zwitterionic polymer exhibited excellent stability in both extracellular and intracellular pH environments and well encapsulated the antitumor drug DOX, and has the potential to improve smart drug delivery and enhance antitumor efficacy for biomedical applications.

scholarly journals Bioceramics: from bone substitutes to nanoparticles for drug delivery

2019 ◽  
Vol 91 (4) ◽  
pp. 687-706 ◽  
Author(s):  
María Vallet-Regí
Keyword(s):  
Drug Delivery ◽  
Biomedical Applications ◽  
Drug Delivery Systems ◽  
Bone Repair ◽  
Research Team ◽  
Research Work ◽  
Bone Substitutes ◽  
Delivery Systems ◽  
Smart Drug ◽  
Smart Drug Delivery

Abstract Since the second half of the 20th century, bioceramics are used for bone repair and regeneration. Inspired by bones and teeth, and aimed at mimicking their structure and composition, several artificial bioceramics were developed for biomedical applications. And nowadays, in the 21st century, with the increasing prominence of nanoscience and nanotechnology, certain bioceramics are being used to build smart drug delivery systems, among other applications. This minireview will mainly describe both tendencies through the research work carried out by the research team of María Vallet-Regí.

Adult Stem Cells and Biocompatible Scaffolds as Smart Drug Delivery Tools for Cardiac Tissue Repair

2013 ◽  
Vol 20 (28) ◽  
pp. 3429-3447 ◽  
Author(s):  
Stefania Pagliari ◽  
Sara Romanazzo ◽  
Diogo Mosqueira ◽  
Perpetua Pinto-do-O ◽  
Takao Aoyagi ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Stem Cells ◽  
Tissue Repair ◽  
Adult Stem Cells ◽  
Cardiac Tissue ◽  
Smart Drug ◽  
Smart Drug Delivery

Advances in Nanoparticles as Anticancer Drug Delivery Vector: Need of this Century

2020 ◽  
Vol 26 (15) ◽  
pp. 1637-1649 ◽  
Author(s):  
Imran Ali ◽  
Sofi D. Mukhtar ◽  
Heyam S. Ali ◽  
Marcus T. Scotti ◽  
Luciana Scotti
Keyword(s):  
Drug Delivery ◽  
Anticancer Drug ◽  
Medical Science ◽  
Drug Carriers ◽  
Anticancer Drug Delivery ◽  
Ph Values ◽  
Delivery Vector ◽  
Future Challenges ◽  
Smart Drug ◽  
Smart Drug Delivery

Background: Nanotechnology has contributed a great deal to the field of medical science. Smart drugdelivery vectors, combined with stimuli-based characteristics, are becoming increasingly important. The use of external and internal stimulating factors can have enormous benefits and increase the targeting efficiency of nanotechnology platforms. The pH values of tumor vascular tissues are acidic in nature, allowing the improved targeting of anticancer drug payloads using drug-delivery vectors. Nanopolymers are smart drug-delivery vectors that have recently been developed and recommended for use by scientists because of their potential targeting capabilities, non-toxicity and biocompatibility, and make them ideal nanocarriers for personalized drug delivery. Method: The present review article provides an overview of current advances in the use of nanoparticles (NPs) as anticancer drug-delivery vectors. Results: This article reviews the molecular basis for the use of NPs in medicine, including personalized medicine, personalized therapy, emerging vistas in anticancer therapy, nanopolymer targeting, passive and active targeting transports, pH-responsive drug carriers, biological barriers, computer-aided drug design, future challenges and perspectives, biodegradability and safety. Conclusions: This article will benefit academia, researchers, clinicians, and government authorities by providing a basis for further research advancements.

Multi-responsive core-crosslinked poly (thiolether ester) micelles for smart drug delivery

Polymer ◽  
2017 ◽  
Vol 110 ◽  
pp. 235-241 ◽  
Author(s):  
Yanfang Hu ◽  
Ming Deng ◽  
Huailin Yang ◽  
Li Chen ◽  
Chunsheng Xiao ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Smart Drug ◽  
Smart Drug Delivery

Diatom mediated smart drug delivery system

2021 ◽  
Vol 63 ◽  
pp. 102433
Author(s):  
Sakshi Phogat ◽  
Abhishek Saxena ◽  
Neha Kapoor ◽  
Charu Aggarwal ◽  
Archana Tiwari
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Smart Drug ◽  
Smart Drug Delivery

scholarly journals Nanochitosan: Commemorating the Metamorphosis of an ExoSkeletal Waste to a Versatile Nutraceutical

Nanomaterials ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 821
Author(s):  
Iyyakkannu Sivanesan ◽  
Manikandan Muthu ◽  
Judy Gopal ◽  
Nazim Hasan ◽  
Syed Kashif Ali ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Biomedical Applications ◽  
Antitumor Drug ◽  
Organic Polymer ◽  
Clinical Settings ◽  
Future Perspectives ◽  
Research Focus ◽  
Nano Structures

Chitin (poly-N-acetyl-D-glucosamine) is the second (after cellulose) most abundant organic polymer. In its deacetylated form—chitosan—becomes a very interesting material for medical use. The chitosan nano-structures whose preparation is described in this article shows unique biomedical value. The preparation of nanochitosan, as well as the most vital biomedical applications (antitumor, drug delivery and other medical uses), have been discussed in this review. The challenges confronting the progress of nanochitosan from benchtop to bedside clinical settings have been evaluated. The need for inclusion of nano aspects into chitosan research, with improvisation from nanotechnological inputs has been prescribed for breaking down the limitations. Future perspectives of nanochitosan and the challenges facing nanochitosan applications and the areas needing research focus have been highlighted.

scholarly journals Erratum: Corrigendum: Doxorubicin-loaded platelets as a smart drug delivery system: An improved therapy for lymphoma

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Peipei Xu ◽  
Huaqin Zuo ◽  
Bing Chen ◽  
Ruju Wang ◽  
Arsalan Ahmed ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Smart Drug ◽  
Smart Drug Delivery
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