Effect of surface modification on the in vitro calcium phosphate growth on the surface of poly(methyl methacrylate) and bioactivity

2010 ◽  
Vol 76 (1) ◽  
pp. 326-333 ◽  
Author(s):  
Sun-Mi Choi ◽  
Won-Kyu Yang ◽  
Yong-Won Yoo ◽  
Woo-Kul Lee
Keyword(s):  
Surface Modification ◽  
Calcium Phosphate ◽  
Methyl Methacrylate ◽  
Poly Methyl Methacrylate ◽  
Effect Of Surface

scholarly journals Graphene-Doped Poly (Methyl-Methacrylate) (Pmma) Implants: A Micro-CT and Histomorphometrical Study in Rabbits

2021 ◽  
Vol 22 (3) ◽  
pp. 1441
Author(s):  
Antonio Scarano ◽  
Tiziana Orsini ◽  
Fabio Di Carlo ◽  
Luca Valbonetti ◽  
Felice Lorusso
Keyword(s):  
Methyl Methacrylate ◽  
Dental Implant ◽  
Animal Studies ◽  
White Male ◽  
Biological Response ◽  
Medullary Canal ◽  
Poly Methyl Methacrylate ◽  
Titanium Surfaces ◽  
Dental Applications

Background—the graphene-doping procedure represents a useful procedure to improve the mechanical, physical and biological response of several Polymethyl methacrylate (PMMA)-derived polymers and biomaterials for dental applications. The aim of this study was to evaluate osseointegration of Graphene doped Poly(methyl methacrylate) (GD-PMMA) compared with PMMA as potential materials for dental implant devices. Methods—eighteen adult New Zealand white male rabbits with a mean weight of approx. 3000 g were used in this research. A total of eighteen implants of 3.5 mm diameter and 11 mm length in GD-PMMA and eighteen implants in PMMA were used. The implants were placed into the articular femoral knee joint. The animals were sacrificed after 15, 30 and 60 days and the specimens were evaluated by µCT and histomorphometry. Results—microscopically, all 36 implants, 18 in PMMA and 18 in DG-PMMA were well-integrated into the bone. The implants were in contact with cortical bone along the upper threads, while the lower threads were in contact with either newly formed bone or with marrow spaces. The histomorphometry and µCT evaluation showed that the GP-PMMA and PMMA implants were well osseointegrated and the bone was in direct contact with large portions of the implant surfaces, including the space in the medullary canal. Conclusions—in conclusion, the results suggest that GD-PMMA titanium surfaces enhance osseointegration in rabbit femurs. This encourages further research to obtain GD-PMMA with a greater radiopacity. Also, further in vitro and vivo animal studies are necessary to evaluate a potential clinical usage for dental implant applications.

In Vitro Mineralization and Cell Adhesion on Surface Modified Poly (2 - hydroxy ethyl methacrylate-co-methyl methacrylate

2006 ◽  
Vol 309-311 ◽  
pp. 493-496 ◽  
Author(s):  
G.S. Sailaja ◽  
T.V. Kumari ◽  
Yoshiyuki Yokogawa ◽  
H.K. Varma
Keyword(s):  
Cell Adhesion ◽  
Calcium Phosphate ◽  
Methyl Methacrylate ◽  
Radical Copolymerization ◽  
Sem Analysis ◽  
Free Radical Copolymerization ◽  
In Vitro Mineralization ◽  
Atr Spectroscopy ◽  
Surface Modified

Poly(2-hydroxyethyl methacrylate-co- methyl methacrylate) HM, was synthesized by free radical copolymerization, cross-linked with ethylene glycol dimethacrylate and phosphorylated. The phosphate coupling was ensured by ATR spectroscopy. The in vitro mineralization ability of the phosphorylated HM (designated as PHM) was investigated by studying the nucleation and growth of calcium phosphate on its surface by immersing in simulated body fluid (SBF) solution. The coating morphology was studied by SEM and the Ca/P ratio of the coating by EDX analysis. The cell adhesion behaviour of PHM was studied by seeding Human osteosarcoma (HOS) cells for one week followed by SEM analysis along with HM as control. It was observed that HOS cells exhibited biomineralization of calcium phosphate on the surface of HM as well as on PHM with a significantly higher amount on the surface of PHM as observed by von kossa staining method. The results show that PHM is capable of in vitro mineralization under simulated physiological condition, promotes cell adhesion by providing an excellent cell friendly surface and it exhibits biomineralization of calcium phosphate in presence of HOS cells.

scholarly journals Preparation and in vitro characterization of valsartan-loaded ethyl cellulose and poly(methyl methacrylate) nanoparticles

RSC Advances ◽  
2020 ◽  
Vol 10 (72) ◽  
pp. 43915-43926
Author(s):  
Eszter Hajba-Horváth ◽  
Emese Biró ◽  
Mirella Mirankó ◽  
Andrea Fodor-Kardos ◽  
László Trif ◽  
...  
Keyword(s):  
Methyl Methacrylate ◽  
Intestinal Absorption ◽  
Ethyl Cellulose ◽  
Active Agent ◽  
Poly Methyl Methacrylate ◽  
In Vitro Characterization ◽  
Spray Dried

Valsartan-loaded ethyl cellulose and poly(methyl methacrylate) nanoparticles were prepared and nano spray-dried. The active agent was structurally changed in the nanoparticles, which could be advantageous in the intestinal absorption.

Surface modification of poly(methyl methacrylate) film by siloxane graft copolymers

1985 ◽  
Vol 18 (3) ◽  
pp. 580-582 ◽  
Author(s):  
Yuhsuke Kawakami ◽  
Toshiki Aoki ◽  
Yuya Yamashita ◽  
Masakazu Hirose ◽  
Akira Ishitani
Keyword(s):  
Surface Modification ◽  
Methyl Methacrylate ◽  
Graft Copolymers ◽  
Poly Methyl Methacrylate

Use of Sonication and Influence of Clay Type on the Enhancement in Physical Properties of Poly(methyl methacrylate) Nanocomposites

2007 ◽  
Vol 1056 ◽  
Author(s):  
Sharon Ingram ◽  
Hugh Dennis ◽  
Ian Hunter ◽  
John J Liggat ◽  
Craig McAdam ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Surface Modification ◽  
Methyl Methacrylate ◽  
Physical Properties ◽  
Resin Composite ◽  
Clay Platelet ◽  
Poly Methyl Methacrylate ◽  
Cure Characteristics ◽  
Clay Type

ABSTRACTThe nature of the dispersion of a clay platelet in a resin composite will play an important role in the process of enhancement of the physical properties of that material. This paper describes studies of ultrasonically and mechanically mixed dispersion of various clays in methyl methacrylate (MMA) and reports the effects of organic surface modification on the rheology, suppression of settlement of filled systems, cure characteristics and final mechanical properties.

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