Nanoparticles modified with cell penetrating peptides: Assessing adsorption on membranes containing acidic lipids

Colloids and Surfaces B Biointerfaces ◽

10.1016/j.colsurfb.2020.111373 ◽

2021 ◽

Vol 197 ◽

pp. 111373

Author(s):

María V. Chiarpotti ◽

Gabriel S. Longo ◽

Mario G. Del Pópolo

Keyword(s):

Cell Penetrating Peptides ◽

Cell Penetrating ◽

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Thermodynamics of cell penetrating peptides on lipid membranes: sequence and membrane acidity regulate surface binding

Physical Chemistry Chemical Physics ◽

10.1039/d0cp02770g ◽

2020 ◽

Vol 22 (40) ◽

pp. 23399-23410

Author(s):

Pedro G. Ramírez ◽

Mario G. Del Pópolo ◽

Jorge A. Vila ◽

Gabriel S. Longo

Keyword(s):

Lipid Membranes ◽

Cell Penetrating Peptides ◽

Surface Binding ◽

Cell Penetrating ◽

Acidic lipids respond to pH in ways that fully promote or deplete the surface accumulation of cell penetrating peptides.

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Faculty Opinions recommendation of Tumor imaging by means of proteolytic activation of cell-penetrating peptides.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1022989.284802 ◽

2005 ◽

Author(s):

Wen-hong Li

Keyword(s):

Tumor Imaging ◽

Cell Penetrating Peptides ◽

Proteolytic Activation ◽

Cell Penetrating

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Faculty Opinions recommendation of Activatable cell penetrating peptides linked to nanoparticles as dual probes for in vivo fluorescence and MR imaging of proteases.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.5869957.5858055 ◽

2011 ◽

Author(s):

Donald A Tomalia

Keyword(s):

Cell Penetrating Peptides ◽

In Vivo Fluorescence ◽

Cell Penetrating

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Faculty Opinions recommendation of Cytotoxicity of prion protein-derived cell-penetrating peptides is modulated by pH but independent of amyloid formation.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.726937665.793537425 ◽

2017 ◽

Author(s):

Chandra Verma ◽

Suryani Lukman

Keyword(s):

Prion Protein ◽

Cell Penetrating Peptides ◽

Amyloid Formation ◽

Cell Penetrating

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Faculty Opinions recommendation of The Argi system: one-step purification of proteins tagged with arginine-rich cell-penetrating peptides.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.727683574.793533691 ◽

2017 ◽

Author(s):

Mario Lebendiker

Keyword(s):

Cell Penetrating Peptides ◽

Cell Penetrating ◽

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Antimicrobial and Cell-Penetrating Peptides: Structure, Assembly and Mechanisms of Membrane Lysis via Atomistic and Coarse-Grained Molecular Dynamic Simulations

Protein and Peptide Letters ◽

10.2174/0929866511009011313 ◽

2010 ◽

Vol 17 (11) ◽

pp. 1313-1327 ◽

Author(s):

Peter J. Bond ◽

Syma Khalid

Keyword(s):

Molecular Dynamic ◽

Cell Penetrating Peptides ◽

Coarse Grained ◽

Molecular Dynamic Simulations ◽

Dynamic Simulations ◽

Membrane Lysis ◽

Cell Penetrating ◽

Structure Assembly

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In Vivo Delivery of Morpholino Oligos by Cell-Penetrating Peptides

Current Pharmaceutical Design ◽

10.2174/1381612811319160010 ◽

2013 ◽

Vol 19 (16) ◽

pp. 2963-2969 ◽

Author(s):

Hong M. Moulton

Keyword(s):

Cell Penetrating Peptides ◽

Cell Penetrating ◽

In Vivo Delivery

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Cell Penetrating Peptides and the Mechanisms for Intracellular Entry

Current Pharmaceutical Biotechnology ◽

10.2174/1389201015666140617093331 ◽

2014 ◽

Vol 15 (3) ◽

pp. 192-199 ◽

Author(s):

Young Choi ◽

Allan David

Keyword(s):

Cell Penetrating Peptides ◽

Cell Penetrating

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Harnessing the Capacity of Cell-Penetrating Peptides for Drug Delivery to the Central Nervous System

Current Pharmaceutical Biotechnology ◽

10.2174/1389201015666140617094952 ◽

2014 ◽

Vol 15 (3) ◽

pp. 220-230 ◽

Author(s):

Ting Kang ◽

Xiaoling Gao ◽

Jun Chen

Keyword(s):

Drug Delivery ◽

Central Nervous System ◽

Nervous System ◽

Cell Penetrating Peptides ◽

Cell Penetrating ◽

The Central Nervous System

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Oncolytic Coxsackievirus and the Mechanisms of its Effects on Cancer: A Narrative Review

Current Cancer Therapy Reviews ◽

10.2174/1573394716999201228215537 ◽

2020 ◽

Vol 16 ◽

Author(s):

Ali Ahmadi ◽

Hadi Esmaeili Gouvarchin Ghaleh ◽

Ruhollah Dorostkar ◽

Mahdieh Farzanehpour ◽

Masoumeh Bolandian

Keyword(s):

Genetic Disease ◽

Control Cell ◽

Gene Mutations ◽

Therapeutic Agents ◽

Cell Penetrating Peptides ◽

Triggered Release ◽

New Techniques ◽

Viral Therapy ◽

Cell Penetrating ◽

Cancer Cell Targeting

Abstract:: Cancer is a genetic disease triggered by gene mutations, which control cell growth and their functionality inherited from previous generations. The targeted therapy of some tumors was not especially successful. A host of new techniques can be used to treat aptamer-mediated targeting, cancer immunotherapy, cancer stem cell (CSC) therapy, cell-penetrating peptides (CPPs), hormone therapy, intracellular cancer cell targeting, nanoparticles, and viral therapy. These include chemical-analog conjugation, gene delivery, ligand-receptor-based targeting, prodrug therapies, and triggered release strategies. Virotherapy is a biotechnological technique for turning viruses into therapeutic agents by the reprogramming of viruses to cure diseases. In several tumors, including melanoma, multiple myeloma, bladder cancer, and breast cancer, the oncolytic capacity of oncolytic Coxsackievirus has been studied. The present study aims to assess oncolytic Coxsackievirus and its mechanisms of effect on cancer cells.

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