Axial osseous sarcoidosis: rare clinical presentation and radiological findings

2010 ◽  
Vol 65 (2) ◽  
pp. 167-171 ◽  
Author(s):  
S. Yanny ◽  
A.P. Toms ◽  
D. MacIver ◽  
T. Barker ◽  
A. Wilson
Keyword(s):  
Clinical Presentation ◽  
Radiological Findings ◽  
Osseous Sarcoidosis

scholarly journals Splenic Infarction and Infectious Diseases in Korea

2020 ◽  
Author(s):  
Jae Hyoung Im ◽  
Moon-Hyun Chung ◽  
Hye-Jin Lee ◽  
Hea Yoon Kwon ◽  
JiHyeon Baek ◽  
...  
Keyword(s):  
Risk Factors ◽  
Immune Cells ◽  
Clinical Presentation ◽  
Scrub Typhus ◽  
Systemic Infection ◽  
Splenic Infarction ◽  
University Hospital ◽  
Radiological Findings ◽  
Epstein Barr ◽  
The Relationship

Abstract Background The spleen contains immune cells and exhibits a pattern of infarction different from other organs; as such, splenic infarction (SI) may provide important clues to infection. However, the nature of the relationship between SI and infectious disease(s) is not well understood. Accordingly, this retrospective study investigated the relationship between SI and infection. Methods Hospital records of patients with SI, who visited Inha University Hospital (Incheon, Republic of Korea) between January 2008 and December 2018, were reviewed. Patient data regarding clinical presentation, causative pathogens, risk factors, and radiological findings were collected and analyzed.Results Of 353 patients with SI, 101 with infectious conditions were enrolled in this study, and their data were analyzed to identify associations between SI and infection. Ten patients were diagnosed with infective endocarditis (IE), and 26 exhibited bacteremia without IE. Twenty-seven patients experienced systemic infection due to miscellaneous causes (negative result on conventional automated blood culture), including the following intracellular organisms: parasites (malaria [n =12], babesiosis [n =1]); bacteria (scrub typhus [n =5]); viruses (Epstein–Barr [n =1], cytomegalovirus [n =1]); and unidentified pathogen[s] (n =7). Splenomegaly was more common among patients with miscellaneous systemic infection; infarction involving other organs was rare. Thirty-eight patients had localized infections (e.g., respiratory, intra-abdominal, or skin and soft tissue infection), and most (35 of 38) had other risk factors for SI. Conclusions In this study, various infectious conditions were found to be associated with SI, and intracellular organisms were the most common causative pathogens. Further studies are needed to examine other possible etiologies and the underlying pathophysiological mechanisms.

scholarly journals Isolated leptomeningeal angiomatosis in the sixth decade of life, an adulthood variant of Sturge Weber Syndrome (Type III): role of advanced Magnetic Resonance Imaging and Digital Subtraction Angiography in diagnosis

BMC Neurology ◽  
2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Vetrivel Muralidharan ◽  
Gaetano Failla ◽  
Mario Travali ◽  
Tiziana Liliana Cavallaro ◽  
Marco Angelo Politi
Keyword(s):  
Clinical Presentation ◽  
Subcortical White Matter ◽  
Digital Subtraction ◽  
Resonance Imaging ◽  
Radiological Findings ◽  
Hyperintense Signal ◽  
Right Cerebral Hemisphere ◽  
Weber Syndrome ◽  
Sturge Weber Syndrome ◽  
The Right

Abstract Background Sturge-Weber syndrome (SWS) is primarily diagnosed in pediatric population, but clinical presentation in late adulthood is rarely reported. Evolution of radiological findings in the adulthood variant of SWS with isolated leptomeningeal angiomatosis has never been reported to our knowledge. Case presentation We report here a case of an isolated temporo-parieto-occipital leptomeningeal angiomatosis on the right cerebral hemisphere in a sixty-two-year-old male who presented with generalized seizure, GCS score 14/15 (E4 V4 M6) with equal and reacting pupils, psychomotor slowing, left hemineglect and grade 4 power in the left upper and lower limbs. Over a period of 48 h his neurological status deteriorated, but recovered spontaneously over a week on titration with anticonvulsants. He had a prior history of treatment for focal leptomeningitis, three years ago. Cerebrospinal fluid (CSF) analysis showed glucose of 75 mg/dL, proteins of 65 mg/dL and culture grew no organisms. On follow-up, he had intermittent episodes of focal seizure for two years. Initial, computed tomography of brain showed hyperdense lesion in the parieto-occipital convexity subarachnoid space on the right cerebral hemisphere mimicking subarachnoid hemorrhage and computed tomography angiography showed no significant abnormality. Magnetic resonance imaging (MRI) of brain showed intense pial enhancement in the right temporo-parieto-occipital region with a subtle T2W hyperintense signal in the underlying subcortical white matter without edema or infarct or mass effect. Digital subtraction cerebral angiography (DSA) showed hypertrophy of the cerebral arteries, arteriolo-capillary bed and venules in the right temporo-parieto-occipital territory associated with early arterio-capillary and venous opacification. Serial MRI done after six months, one and two years showed increase in the T2W hyperintense signal in the subcortical white matter and cortical atrophy with no changes in the pial enhancement. MR perfusion imaging showed reduced cerebral blood flow (CBF) and cerebral blood volume (CBV) in the right parieto-temporo-occipital cortical and subcortical regions and increased perfusion in the leptomeninges with reduction of the NAA / Cr ratios in spectroscopy. Conclusion Conglomeration of various radiological findings in MRI, Perfusion, MRS and DSA with the clinical presentation can aid in establishing the diagnosis of this rare presentation of SWS-type 3 variant in late adulthood.

scholarly journals Lymphocytic colitis: clinical presentation and long term course

Gut ◽  
1998 ◽  
Vol 43 (5) ◽  
pp. 629-633 ◽  
Author(s):  
B Mullhaupt ◽  
U Güller ◽  
M Anabitarte ◽  
R Güller ◽  
M Fried
Keyword(s):  
Colonic Mucosa ◽  
Clinical Presentation ◽  
Collagenous Colitis ◽  
Endoscopic Examination ◽  
Watery Diarrhoea ◽  
Lymphocytic Colitis ◽  
Radiological Findings ◽  
Benign Course

Background—Lymphocytic colitis is characterised by chronic watery diarrhoea with normal endoscopic or radiological findings and microscopic evidence of pronounced infiltration of the colonic mucosa with lymphocytes.Aim—To investigate the long term clinical and histological evolution of the disease in a large group of patients with well characterised lymphocytic colitis.Methods—Between 1986 and 1995 the histological diagnosis of lymphocytic colitis was obtained in 35 patients; 27 of these agreed to a follow up examination. All clinical, endoscopic, and histopathological records were reviewed at that time and the patients had a second endoscopic examination with follow up biopsies.Results—The patients initially presented with the typical findings of lymphocytic colitis. After a mean (SD) follow up of 37.8 (27.5) months, diarrhoea subsided in 25 (93%) and histological normalisation was observed in 22 (82%) of the 27 patients. Progression from lymphocytic colitis to collagenous colitis was not observed.Conclusions—Lymphocytic colitis is characterised by a benign course with resolution of diarrhoea and normalisation of histology in over 80% of patients within 38 months. Considering the benign course of the disease, the potential benefit of any drug treatment should be carefully weighed against its potential side effects.

Acute fulminant fungal sinusitis: clinical presentation, radiological findings and treatment

Acta Tropica ◽  
2001 ◽  
Vol 80 (2) ◽  
pp. 177-185 ◽  
Author(s):  
M.A. Sohail ◽  
Mazin Al Khabori ◽  
Jamil Hyder ◽  
Ashok Verma
Keyword(s):  
Clinical Presentation ◽  
Fungal Sinusitis ◽  
Radiological Findings

scholarly journals A Rare Case of Radiation-Induced Osteosarcoma of the Ethmoid Sinus

2011 ◽  
Vol 2011 ◽  
pp. 1-3
Author(s):  
Musaed Alzahrani ◽  
Alain Robier ◽  
Yoann Pointreau ◽  
David Bakhos
Keyword(s):  
Magnetic Resonance Imaging ◽  
Rare Case ◽  
Clinical Presentation ◽  
Malignant Tumors ◽  
Ethmoid Sinus ◽  
Resonance Imaging ◽  
Radiological Findings ◽  
Initial Exposure ◽  
Secondary Tumors ◽  
Radiation Induced

Radiation therapy has been recognized as a useful modality of treatment in head and neck malignant tumors. However, radiation over 10 Gy may predispose to secondary tumors. Radiation-induced osteosarcoma of the ethmoid sinus is unusual. These tumors may present long after radiation with epistaxis. Computed tomography, magnetic resonance imaging, and biopsy are the modalities of diagnosis. We report a case of radiation-induced osteosarcoma of the ethmoid sinus 9 years after initial exposure. We describe the clinical presentation, the radiological findings, and the management.

Meningiomas of the Pineal Region and Third Ventricle

Neurosurgery ◽  
1979 ◽  
Vol 5 (4) ◽  
pp. 489-495 ◽  
Author(s):  
Rodney Rozario ◽  
Lester Adelman ◽  
Robert J. Prager ◽  
Bennett M. Stein
Keyword(s):  
Clinical Presentation ◽  
English Literature ◽  
Third Ventricle ◽  
Pineal Region ◽  
Radiological Findings ◽  
Total Removal ◽  
True Nature ◽  
Preoperative Diagnostic ◽  
Dural Attachment ◽  
Velum Interpositum

Abstract The clinical presentation, radiological findings, and surgical management of two cases of meningioma arising from the velum interpositum without dural attachment are described. The true nature of these tumors was not suspected despite extensive preoperative diagnostic evaluation. A total removal was effected in both cases with the use of the operating microscope and a posterior fossa approach to the pineal region. A review of similar cases from the English literature is presented.

scholarly journals CADASIL: pathogenesis, clinical and radiological findings and treatment

2010 ◽  
Vol 68 (2) ◽  
pp. 287-299 ◽  
Author(s):  
Charles André
Keyword(s):  
Progressive Disease ◽  
Autosomal Dominant ◽  
Clinical Presentation ◽  
Rational Approach ◽  
Radiological Findings ◽  
High Quality ◽  
Cognitive Interventions ◽  
Subcortical Vascular Dementia ◽  
The World ◽  
Variable Clinical Presentation

Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is the most common genetic cause of ischemic strokes and a most important model for the study of subcortical vascular dementia. This unrelentlessly progressive disease affects many hundreds of families all over the world but is not well studied in Brazil. This manuscript reviews pathogenetic, clinical, radiological and therapeutic features of CADASIL. The causal mutations are now very well known, but the same can not be said about its intimate pathogenetic mechanisms. The variable clinical presentation should lead physicians to actively pursue the diagnosis in many settings and to more thouroughly investigate family history in first degree relatives. A rational approach to genetic testing is however needed. Treatment of CADASIL is still largely empiric. High-quality therapeutic studies involving medications and cognitive interventions are strongly needed in CADASIL.

scholarly journals Intracranial Ewing Sarcoma – A case report

2020 ◽  
Vol 11 ◽  
pp. 134
Author(s):  
Jiahua Huang ◽  
Finn Ghent ◽  
Robyn Levingston ◽  
Martin Scholsem
Keyword(s):  
Adjuvant Chemotherapy ◽  
Clinical Presentation ◽  
Treatment Protocol ◽  
Rare Entity ◽  
Round Cell ◽  
Peripheral Primitive Neuroectodermal Tumor ◽  
Radiological Findings ◽  
Adjuvant Chemoradiation ◽  
Total Resection ◽  
Mri Brain

Background: Intracranial Ewing’s sarcoma (ES) is a rare entity with <15 cases reported in the literature. It belongs to a family of round-cell neuroectodermally derived tumors bearing many similarities to peripheral primitive neuroectodermal tumor (pPNET). There is currently no established treatment protocol. Reported cases are treated with either surgery alone or surgery with adjuvant chemotherapy and radiation. Case Description: We describe a case of intracranial left frontal ES in a 19-year-old patient who presented with change in behavior. Diagnosis was unclear based on radiological findings on MRI and CT alone. MRI brain with contrast demonstrated a large extra-axial ovoid heterogeneously enhancing left frontal convexity mass. The patient underwent gross total resection with adjuvant chemotherapy and radiation. No local or systemic recurrence was found at 12 months postoperatively. Conclusion: Intracranial ES/pPNET is rare tumor with nonspecific clinical presentation and radiological findings. They are locally invasive. Surgery with adjuvant chemoradiation is the mainstay treatment. Distinction of pPNET and cPNET is important for therapeutic and prognostic purposes.

scholarly journals The Lung Mass and nodule: a case series

2021 ◽  
Author(s):  
Azam Jan ◽  
Naseer Ahmed ◽  
Nabil Iftikhar Awan ◽  
Bahauddin Khan ◽  
Mujahid-ul Islam ◽  
...  
Keyword(s):  
Clinical Presentation ◽  
Correct Diagnosis ◽  
Case Series ◽  
Female Child ◽  
Lung Mass ◽  
Radiological Findings ◽  
X Ray ◽  
Smoking Exposure ◽  
Poorly Differentiated ◽  
Timely Treatment

Lung mass is an abnormal region of 3 cm or more in size present in the lungs mainly due to underlying pulmonary caner. It is usually round, opaque and poorly differentiated on X-ray. Common etiological key players are smoking, exposure to asbestos, radon, however, familial history may also play a role. We presented retrospectively 7 cases of lung mass and nodule encountered during our clinical practice. We have discussed their clinical presentation, manifestation, medical history, radiological findings and differential diagnosis. In this case series, most of the patients were young, only 2 cases were older patients. There was one infant one month old, one female child 12 years old, one female 25 years, 2 males, 22 and 21 years, one male of 50 years and another male of 60 years age. Correct diagnosis on the basis of clinical profile, radiological findings and histology may help in proper management and hence, timely treatment of the patient.

scholarly journals A Rare Case of Synovial Osteochondromatosis of the Elbow

2019 ◽  
pp. 49
Author(s):  
Loh Li Loong ◽  
Wong Kai An ◽  
Zamzuri Zakaria @Mohamad
Keyword(s):  
Clinical Presentation ◽  
Histopathological Examination ◽  
Tissue Sample ◽  
Excisional Biopsy ◽  
Synovial Chondromatosis ◽  
Loose Body ◽  
Radiological Findings ◽  
Arthroscopic Synovectomy ◽  
Rare Presentation ◽  
Synovial Osteochondromatosis

We report here a rare presentation of a primary synovial osteochondromatosis of the elbow. Clinical presentation and radiological findings were suggestive of synovial osteochondromatosis. Arthroscopic synovectomy, debridement, excisional biopsy and loose body removal was performed and histopathological examination of the tissue sample is consistent with the diagnosis of synovial osteochondromatosis. This article highlights the surgical technique in managing synovial chondromatosis to achieve better functional outcome

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