The beneficial role of vitamin D and its analogs in cancer treatment and prevention

2010 ◽  
Vol 73 (3) ◽  
pp. 192-201 ◽  
Author(s):  
Khanh vinh quoc Luong ◽  
Lan Thi Hoang Nguyen
Keyword(s):  
Vitamin D ◽  
Cancer Treatment ◽  
Beneficial Role ◽  
Treatment And Prevention

The role of vitamin D in metabolic and reproductive disturbances of polycystic ovary syndrome: A narrative mini-review

2020 ◽  
pp. 1-8
Author(s):  
Daniela Menichini ◽  
Gianpiero Forte ◽  
Beatrice Orrù ◽  
Giuseppe Gullo ◽  
Vittorio Unfer ◽  
...  
Keyword(s):  
Vitamin D ◽  
Polycystic Ovary Syndrome ◽  
Embryo Quality ◽  
Polycystic Ovary ◽  
Vitamin D Supplementation ◽  
Endometrial Receptivity ◽  
Metabolic Disturbances ◽  
Ovary Syndrome ◽  
Beneficial Role

Abstract. Vitamin D is a secosteroid hormone that plays a pivotal role in several metabolic and reproductive pathways in humans. Increasing evidence supports the role of vitamin D deficiency in metabolic disturbances and infertility in women with polycystic ovary syndrome (PCOS). Indeed, supplementation with vitamin D seems to have a beneficial role on insulin resistance and endometrial receptivity. On the other hand, exceedingly high levels of vitamin D appear to play a detrimental role on oocytes development and embryo quality. In the current review, we summarize the available evidence about the topic, aiming to suggest the best supplementation strategy in women with PCOS or, more generally, in those with metabolic disturbances and infertility. Based on the retrieved data, vitamin D seems to have a beneficial role on IR, insulin sensitivity and endometrial receptivity, but high levels and incorrect timing of administration seem to have a detrimental role on oocytes development and embryo quality. Therefore, we encourage a low dose supplementation (400–800 IU/day) particularly in vitamin D deficient women that present metabolic disturbances like PCOS. As far as the reproductive health, we advise vitamin D supplementation in selected populations, only during specific moments of the ovarian cycle, to support the luteal phase. However, ambiguities about dosage and timing of the supplementation still emerge from the clinical studies published to date and further studies are required.

Role of Unani Medicines in Cancer Control and Management

2019 ◽  
Vol 14 (2) ◽  
pp. 92-113 ◽  
Author(s):  
Imran Ali ◽  
Mohd. Suhail ◽  
Mohd. Farooq Naqshbandi ◽  
Mohd. Fazil ◽  
Bilal Ahmad ◽  
...  
Keyword(s):  
Cancer Treatment ◽  
Digestive System ◽  
Cancer Control ◽  
Terminalia Arjuna ◽  
Herbal Drugs ◽  
Unani Medicine ◽  
Treatment And Prevention ◽  
Prevention Of Cancer ◽  
Control And Management

Background:Cancer is a havoc and killer disease. Several ways including allopathic chemotherapy have been used in the cancer treatment. Allopathic chemotherapy has several limitations and side effects. Unani medicine is also one of the therapies to cure cancer.Objective:In this type of treatment, herbal drugs are used for the treatment and prevention of cancer. The main attractive thing about herbal drug is no side effect as compared to allopathic chemotherapy.Methods:Actually, herbal drugs are the extracts of medicinal plants. The plant extracts are obtained by crushing and heating the main part of the plants; showing anticancer activity. The main plants used in the treatment of cancer are oroxylum indicum, dillenia indica, terminalia arjuna etc.Results:Mainly the cancers treated are of digestive system, breast, cervical, brain, blood, bone, lungs, thyroid, uterine, bladder, throat etc.Conclusion:The present review article discusses the importance of Unani system of medicine for the treatment of cancer. Besides, the future perspectives of Unani medicine in cancer treatment are also highlighted.

scholarly journals Myth Busters: Dietary Supplements and COVID-19

2020 ◽  
Vol 54 (8) ◽  
pp. 820-826 ◽  
Author(s):  
Kathleen K. Adams ◽  
William L. Baker ◽  
Diana M. Sobieraj
Keyword(s):  
Social Media ◽  
Vitamin D ◽  
Vitamin C ◽  
Dietary Supplements ◽  
Evidence Based ◽  
Efficacy And Safety ◽  
Treatment And Prevention ◽  
Social Media Platforms ◽  
Evidence Based Guidelines

News and social media platforms have implicated dietary supplements in the treatment and prevention of coronavirus disease 2019 (COVID-19). During this pandemic when information quickly evolves in the presence of contradicting messages and misinformation, the role of the pharmacist is essential. Here, we review theoretical mechanisms and evidence related to efficacy and safety of select supplements in the setting of COVID-19, including vitamin C, vitamin D, zinc, elderberry, and silver. Evidence evaluating these supplements in COVID-19 patients is lacking, and providers and patients should not rely on dietary supplements to prevent or treat COVID-19. Rather, reference to evidence-based guidelines should guide treatment decisions.

scholarly journals Vitamin D and COVID-19: An Overview of Recent Evidence

2021 ◽  
Vol 22 (19) ◽  
pp. 10559
Author(s):  
Drishti Ghelani ◽  
Simon Alesi ◽  
Aya Mousa
Keyword(s):  
Vitamin D ◽  
Effective Means ◽  
Adaptive Immune System ◽  
Vitamin D Supplementation ◽  
The Novel ◽  
Treatment And Prevention ◽  
Global Pandemic ◽  
Low Levels ◽  
Novel Coronavirus

The novel coronavirus severe acute respiratory syndrome (SARS-CoV-2) has progressed rapidly from an outbreak to a global pandemic, with new variants rapidly emerging. Coronavirus disease 2019 (COVID-19), the disease resulting from SARS-CoV-2 infection, can lead to multiorgan damage. Due to the extremely contagious and fatal nature of the virus, it has been a priority of medical research to find effective means of treatment. Amid this search, the role of vitamin D in modulating various aspects of the innate and adaptive immune system has been discussed. This review aims to consolidate the research surrounding the role of vitamin D in the treatment and prevention of COVID-19. While there are some conflicting results reported, the consensus is that vitamin D has a host of immunomodulatory effects which may be beneficial in the context of COVID-19 and that low levels of vitamin D can result in dysfunction of crucial antimicrobial effects, potentially contributing to poor prognosis. Studies also show that the effects of low vitamin D can be mitigated via supplementation, although the benefits of vitamin D supplementation in the treatment of COVID-19 remain controversial.

scholarly journals Potential Role of UGT Pharmacogenetics in Cancer Treatment and Prevention

2009 ◽  
Vol 1155 (1) ◽  
pp. 99-111 ◽  
Author(s):  
Philip Lazarus ◽  
Andrea S. Blevins-Primeau ◽  
Yan Zheng ◽  
Dongxiao Sun
Keyword(s):  
Cancer Treatment ◽  
Potential Role ◽  
Treatment And Prevention
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