The interplay of YKL-40 and leptin in type 2 diabetic obese patients

2011 ◽  
Vol 93 (3) ◽  
pp. e113-e116 ◽  
Author(s):  
Hala O. El-Mesallamy ◽  
Ahmed M. Mostafa ◽  
Ashraf I. Amin ◽  
Ebtehal El Demerdash
Keyword(s):  
Obese Patients ◽  
Type 2 Diabetic

PP248-SUN: Outstanding abstract: Circadian Rhythms in Healthy, Type 2 Diabetic and Obese Patients: A Preliminary in Vitro Study

2014 ◽  
Vol 33 ◽  
pp. S112
Author(s):  
A.-M. Makhlouf ◽  
P. Meyer ◽  
C. Tran ◽  
Z. Pataky ◽  
J. Philippe ◽  
...  
Keyword(s):  
Circadian Rhythms ◽  
In Vitro Study ◽  
Vitro Study ◽  
Obese Patients ◽  
Type 2 Diabetic

scholarly journals Myocardial Contractile Dysfunction Is Associated With Impaired Mitochondrial Function and Dynamics in Type 2 Diabetic but Not in Obese Patients

Circulation ◽  
2014 ◽  
Vol 130 (7) ◽  
pp. 554-564 ◽  
Author(s):  
David Montaigne ◽  
Xavier Marechal ◽  
Augustin Coisne ◽  
Nicolas Debry ◽  
Thomas Modine ◽  
...  
Keyword(s):  
Mitochondrial Function ◽  
Contractile Dysfunction ◽  
Obese Patients ◽  
Myocardial Contractile ◽  
Type 2 Diabetic

scholarly journals Dietary Diversity as a Risk Factor for Obesity in Algerian Patients with Type 2 Diabetes Mellitus

Healthcare ◽  
2021 ◽  
Vol 9 (9) ◽  
pp. 1229
Author(s):  
Abdenour Bounihi ◽  
Hamza Saidi ◽  
Asma Bouazza ◽  
Hassiba Benbaibeche ◽  
Malha Azzouz ◽  
...  
Keyword(s):  
Physical Activity ◽  
Type 2 Diabetes ◽  
Risk Factor ◽  
Dietary Diversity ◽  
Diabetic Patients ◽  
Obese Patients ◽  
Type 2 Diabetic Patients ◽  
Cross Sectional ◽  
Type 2 Diabetic

Although the incidence of “diabesity” (coexistence of type 2 diabetes and obesity) is alarmingly increasing in Algeria, the diet–diabesity link has not been well defined. This study aimed to explore the association between dietary diversity score (DDS) and obesity among Algerian type 2 diabetic patients. It was a cross-sectional observational study involving 390 type 2 diabetic patients. Anthropometric data were gathered, and dietary intake information was obtained through a 24-h dietary recall method, which was used to calculate DDS. Potential confounders such as age, sex, smoking, physical activity and energy intake were controlled for using multivariate logistic regression. A total of 160 patients (41.3%) were classified as obese. As expected, obese patients had a higher body mass index, waist circumference, hip circumference, body fat and fat mass index. Furthermore, obese patients more frequently met carbohydrate recommendations and had a higher intake of meat and protein. Female sex, hypertension, low physical activity and high meat and protein intake were positively associated with diabesity. Additionally, higher DDS was positively associated with diabesity after adjusting for confounders. Thus, a more diversified diet may be a risk factor for obesity among Algerian type 2 diabetic patients.

scholarly journals Bariatric Surgery Reduces Oxidative Stress by Blunting 24-h Acute Glucose Fluctuations in Type 2 Diabetic Obese Patients

Diabetes Care ◽  
2009 ◽  
Vol 33 (2) ◽  
pp. 287-289 ◽  
Author(s):  
R. Marfella ◽  
M. Barbieri ◽  
R. Ruggiero ◽  
M. R. Rizzo ◽  
R. Grella ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Bariatric Surgery ◽  
Obese Patients ◽  
Glucose Fluctuations ◽  
Type 2 Diabetic

scholarly journals Circulating C1q/TNF-Related Protein 3, Omentin-1 and NGAL in Obese Patients with Type 2 Diabetes During Insulin Therapy

2019 ◽  
Vol 8 (6) ◽  
pp. 805 ◽  
Author(s):  
Katarzyna Komosinska-Vassev ◽  
Pawel Olczyk ◽  
Kornelia Kuźnik-Trocha ◽  
Agnieszka Jura-Półtorak ◽  
Alicja Derkacz ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Plasma Concentration ◽  
Insulin Therapy ◽  
Diabetic Patients ◽  
Obese Patients ◽  
Related Protein ◽  
Type 2 Diabetic Patients ◽  
Plasma Profile ◽  
Type 2 Diabetic

The aim of the study was to quantify the plasma concentration of omentin-1, neutrophil gelatinase-associated lipocalin (NGAL), and complement C1q tumor necrosis factor-related protein-3 (CTRP3) in obese patients with type 2 diabetes, before introducing insulin therapy, in relation to the plasma expression profiles of these regulatory molecules in the same patients after a 6-month insulin mixture therapy and in obese controls. Elevated plasma NGAL concentrations were found in type 2 diabetic patients as compared with subjects with metabolically healthy obesity. In turn, a 6-month insulin mixture therapy has shown a marked increase in the plasma concentration of omentine-1 and a significant decrease in plasma CTRP3 concentration in obese patients with type 2 diabetes, in relation to the values found in these patients before the implementation of insulin therapy. Insulin mixture therapy has also proved to be an important factor modifying the plasma profile of NGAL, increasing the concentration of this bioactive molecule in the plasma of patients with type 2 diabetes, after 6 months of its use, in relation to the concentration before treatment. The significant changes in the plasma profile of omentin-1, NGAL and CTRP3 during insulin therapy suggest their potential diagnostic utility in monitoring metabolic changes associated with the introduction of insulin treatment in type 2 diabetic patients.

scholarly journals Effectiveness of Valsartan in Obese Versus Non-Obese Type 2 Diabetic patients presented with microalbuminuria

2021 ◽  
Vol 15 (10) ◽  
pp. 2673-2675
Author(s):  
Muhammad Kashif Khan ◽  
Shakeel Khan ◽  
Ahmad Shamim Khan ◽  
Khawar Sultan ◽  
Armughan Ahmad ◽  
...  
Keyword(s):  
Selection Criteria ◽  
P Value ◽  
Diabetic Patients ◽  
Obese Patients ◽  
Medical Sciences ◽  
Type 2 Diabetic Patients ◽  
Keywords Diabetes ◽  
The Mean ◽  
Type 2 Diabetic

Aim: To ascertain efficacy of Valsartan, an angiotensin receptor blocker (ARB) in reducing microalbuminuria in obese verses non obese patients. Methods: This comparative study was done in Department of Nephrology Pakistan Institute of Medical Sciences Islamabad from July 1, 2018 to December 31, 1018. Patients fulfilling selection criteria were enrolled and categorized as two groups obese & non-obese; both groups were given valsartan. Urine ACR and serum creatinine was followed every month for 6 months. Results: Average age of all cases as 52.06 ± 4.11 years while the mean age in obese and non-obese cases was 52.48 ± 4.25 years and 51.63 ± 3.95 years, respectively. The mean change in Urine ACR (from baseline to 6th months) in obese cases was 41.76 ± 25.81 and non-obese cases was 76.05 ± 7.63, p-value <0.001. In obese cases mean urine ACR at 1st and 2nd month was same from baseline, p-value > 0.05 while at 3rd, 4th month was statistically lower as compare to baseline urine ACR, p-value < 0.05. Moreover, in non-obese cases the mean urine ACR was statistically decreased at 1st, 2nd, 3rd, 4th, 5th and 6th month when compared with baseline, p-value < 0.001. At 4th month in obese cases none of the cases achieved ACR < 30 while in non-obese cases 4(7.4%) cases achieved ACR < 30 with significantly higher frequency in non-obese cases, p-value < 0.05. At 4th month in obese cases 12(22.2%) cases achieved ACR < 30 while in non-obese cases 31(57.4%) cases achieved ACR < 30 with significantly higher frequency in non-obese cases, p-value < 0.001. At 6th month in obese cases 20(37%) cases achieved ACR < 30 while in non-obese cases 41(75.9%) cases achieved ACR < 30 with significantly higher frequency in non-obese cases, p-value < 0.001. Conclusion: Valsartan is more effective in reducing microalbuminuria in non-obese patients as compared to obese patients. Keywords: Diabetes mellitus, obesity, microalbuminuria, Valsartan

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