Association of nesfatin-1 level with body composition, dietary intake and resting metabolic rate in obese and morbid obese subjects

2015 ◽  
Vol 9 (4) ◽  
pp. 292-298 ◽  
Author(s):  
Khadijeh Mirzaei ◽  
Arash Hossein-nezhad ◽  
Seyed Ali Keshavarz ◽  
Fariba Koohdani ◽  
Mohammad Reza Eshraghian ◽  
...  
1991 ◽  
Vol 71 (3) ◽  
pp. 801-806 ◽  
Author(s):  
D. L. Ballor

This study examined the effects of three levels of dietary intake [ad libitum fed (AL), moderately severe (MSR), and severe restriction (SR)] and two levels of exercise [cage confinement (CC) and exercise training (E)] on 23-h resting metabolic rate (RMR) and body composition in 47 female Sprague-Dawley rats. At the end of the 9-wk study, the MSR and SR groups weighed approximately 81 and 61%, respectively, of the AL-CC group. RMR was depressed for the MSR and SR groups compared with the AL-CC group. This was true whether expressed on an absolute (ml/min) or relative (ml.min-1.kg-0.75) basis. On a relative basis, which accounts for changes caused by weight loss alone, the RMR decreased by approximately 12 and 19%, respectively, for the MSR and SR groups compared with the AL-CC group. Although E resulted in significant differences in fat mass, percent fat, percent water, and heart mass between the AL groups, there were no significant differences between E and CC groups at either the MSR or SR level of dietary intake for any of the variables measured (i.e., body composition, muscle mass, RMR). Thus E does not appear to affect the composition of lost weight or RMR during diet-induced weight loss for female rats of normal weight.


2019 ◽  
Vol 14 (5) ◽  
pp. 658-664 ◽  
Author(s):  
Paula B. Costa ◽  
Scott R. Richmond ◽  
Charles R. Smith ◽  
Brad Currier ◽  
Richard A. Stecker ◽  
...  

Synchronized swimming is a sport that requires high levels of strength, power, and endurance, as well as artistic skill to perform in an aquatic environment. Purpose: The purpose of this study was to identify physiological characteristics and dietary habits of collegiate synchronized swimmers. Methods: A total of 21 female participants (mean [SD] age = 20.4 [1.6] y, height = 168.0 [4.9] cm, and weight = 64.4 [8.7] kg) performed resting metabolic rate test. Body composition was determined using skinfolds (4-site and 7-site) and dual-energy X-ray absorptiometry (DEXA). Dietary intake was assessed using 4-d dietary records. Results: Resting metabolic rate was 110.9 (10.5) kJ/kg normalized to body weight and calculated relative daily caloric intake was 121.4 (42.3) kJ/kg. Estimated energy availability ranged from 109.1 (52.1) to 126.7 (52.6) kJ/kg fat-free mass per day and was correlated (P = .045) to resting metabolic rate. Percentage body fat measured using DEXA (28.7% [4.8%] fat) was higher than both 4-site (25.7% [4.8%] fat, P = .001) and 7-site (25.3% [4.7%] fat, P = .001) skinfold values. No significant correlations were reported between bone mineral density, body composition, and dietary intake data. Conclusions: Synchronized swimmers have similar body composition and training habits as other competitive aquatic athletes. Dietary intake data revealed low energy availability and lower than recommended macronutrient levels.


Author(s):  
Madelin R. Siedler ◽  
Eric T. Trexler ◽  
Megan N. Humphries ◽  
Priscila Lamadrid ◽  
Brian Waddell ◽  
...  

An amendment to this paper has been published and can be accessed via the original article.


2015 ◽  
Vol 48 (4) ◽  
pp. 359 ◽  
Author(s):  
Bruno A. P. de Oliveira ◽  
Camila B. Gardim ◽  
Carolina N. Ferreira ◽  
Suziane U. Cayres ◽  
Ismael F. Freitas Junior

Objetivo: Analisar a composição corporal e taxa metabólica de repouso (TMR) de adolescentes com obesidade. Metodologia: Foram avaliados 58 adolescentes, entre 12 e 16 anos (13,7±1,2 anos), com obesidade. A composição corporal foi mensurada por meio da Absortiometria de Raios-x de Dupla Energia (DEXA). A taxa metabólica de repouso e a oxidação de glicose e lipídeos foram determinadas pela medida do oxigênio consumido e pela produção de dióxido de carbono. Foi utilizado teste t de Student para variáveis independentes, análise de regressão linear múltipla e correlação de Pearson, com significância de p<5%. Resultados: Foram observadas diferenças na porcentagem de gordura corporal (p=0,01), porcentagem de massa corporal magra (MCM) (p=0,01), porcentagem de gordura do tronco (p=0,01), massa magra membro inferior (p=0,01) e taxa metabólica de repouso (p=0,04) entre os sexos masculino e feminino. No sexo masculino a MCM foi a melhor preditora de TMR (p=0,01). Houve correlação positiva entre TMR e MCM, assim como observada associação entre a oxidação lipídica e MCM. Conclusão: A composição corporal total e por segmento corporal influenciam a taxa metabólica de repouso e a oxida- ção de substratos. Além disso, a MCM pode ser considerada um fator de aumento do gasto energético de repouso de adolescentes com obesidade.


Nutrients ◽  
2021 ◽  
Vol 13 (10) ◽  
pp. 3394
Author(s):  
Sarah A. Purcell ◽  
Ryan J. Marker ◽  
Marc-Andre Cornier ◽  
Edward L. Melanson

Many breast cancer survivors (BCS) gain fat mass and lose fat-free mass during treatment (chemotherapy, radiation, surgery) and estrogen suppression therapy, which increases the risk of developing comorbidities. Whether these body composition alterations are a result of changes in dietary intake, energy expenditure, or both is unclear. Thus, we reviewed studies that have measured components of energy balance in BCS who have completed treatment. Longitudinal studies suggest that BCS reduce self-reported energy intake and increase fruit and vegetable consumption. Although some evidence suggests that resting metabolic rate is higher in BCS than in age-matched controls, no study has measured total daily energy expenditure (TDEE) in this population. Whether physical activity levels are altered in BCS is unclear, but evidence suggests that light-intensity physical activity is lower in BCS compared to age-matched controls. We also discuss the mechanisms through which estrogen suppression may impact energy balance and develop a theoretical framework of dietary intake and TDEE interactions in BCS. Preclinical and human experimental studies indicate that estrogen suppression likely elicits increased energy intake and decreased TDEE, although this has not been systematically investigated in BCS specifically. Estrogen suppression may modulate energy balance via alterations in appetite, fat-free mass, resting metabolic rate, and physical activity. There are several potential areas for future mechanistic energetic research in BCS (e.g., characterizing predictors of intervention response, appetite, dynamic changes in energy balance, and differences in cancer sub-types) that would ultimately support the development of more targeted and personalized behavioral interventions.


1990 ◽  
Vol 259 (2) ◽  
pp. E233-E238 ◽  
Author(s):  
N. K. Fukagawa ◽  
L. G. Bandini ◽  
J. B. Young

The relationship between fat-free mass (FFM) and resting metabolic rate (RMR) was compared in young men (n = 24; age 18-33 yr), old men (n = 24; 69-89 yr), and old women (n = 20; 67-75 yr). Body composition was assessed using anthropometry, bioelectrical impedance analysis (BIA), and isotope dilution with 18O-labeled water. RMR was measured at least twice using an open-circuit indirect calorimetry system with a ventilated hood. The results indicate that the different methods for assessing body composition vary substantially and should not be used interchangeably. Anthropometry was not adequate to assess group differences in body fatness, although skinfold measures may be appropriate for within-group comparisons. BIA correlated well with the isotope-dilution technique and may be a useful measure of FFM. Finally, RMR was lower in the old men than the young (1.04 +/- 0.02 vs. 1.24 +/- 0.03 kcal/min, P less than 0.001) and remained lower even when adjusted for FFM estimated by isotope dilution (P less than 0.001). RMR in the women was also lower (0.84 +/- 0.02 kcal/min), but in contrast to the difference between young and old men, RMR adjusted for FFM did not differ (P = 0.16) between old men and women. Therefore, it is clear that differences in FFM cannot fully account for the lower RMR in the old, suggesting that aging is associated with an alteration in tissue energy metabolism.


1999 ◽  
Vol 69 (6) ◽  
pp. 1117-1122 ◽  
Author(s):  
Arne Astrup ◽  
Peter C Gøtzsche ◽  
Karen van de Werken ◽  
Claudia Ranneries ◽  
Søren Toubro ◽  
...  

2021 ◽  
Author(s):  
Sandra Aravind Areekal ◽  
Anuradha Khadilkar ◽  
Veena Ekbote ◽  
Neha Kajale ◽  
Arun S. Kinare ◽  
...  

Abstract Resting metabolic rate (RMR) quantifies the minimal energy required to sustain vital body functions and is a crucial component of childhood development. While inter-individual variations in RMR have been studied for over a century they are poorly understood. Wang (Am. J. Hum., 2012) has modelled mean RMR per unit body mass (RMR/BM) in children grouped into age classes one year apart; this model is able to explain the variation in RMR/BM very accurately in a reference Caucasian dataset based on the relative masses of four major organs (liver, kidney, brain, heart) and the residual mass. However, it is not clear if it applies to other ethnicities, especially when the variation in the RMR is observed to be large in a population. Here we address the extent to which such a model can be adapted to explain RMR/BM in Indian children. Here we present two novel phenomenological models that describe the mean RMR/BM stratified by age in Indian children and adolescents, using data from the Multi-Centre Study (MCS) and RMR-USG. MCS is a cross-sectional dataset on 495 (235 girls) children aged 9 to 19 years with anthropometric, body composition and RMR measurements. RMR-USG consists of anthropometric data, RMR, and liver and kidney volume measured through ultrasonography in nine girls and nine boys aged 6 to 8 years. The mean RMR/BM in Indian children is observed to be significantly lower compared to their Caucasian counterparts, except in boys in the age groups 9 to 11 years and 12 to 13 years. The first is a modified Wang model in which the relative masses of four major organs are assumed to be uniformly lowered for Indian children. Theoretical predictions of size are not uniformly borne out in a pilot validation study, however, the relative mass of the kidney is indeed found to be significantly lower. We then present another version of the Wang model to demonstrate that changes in body composition alone can also explain the Indian data. Either model can be thus used phenomenologically to estimate mean RMR/BM by age in Indian children; however, understanding the mechanistic basis of variation in RMR/BM remains an open problem.


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