scholarly journals Dental Disease Outcomes Following a 2-Year Oral Health Promotion Program for Australian Aboriginal Children and Their Families: A 2-Arm Parallel, Single-blind, Randomised Controlled Trial

2018 ◽  
Vol 1 ◽  
pp. 43-50 ◽  
Author(s):  
Lisa Jamieson ◽  
Lisa Smithers ◽  
Joanne Hedges ◽  
Eleanor Parker ◽  
Helen Mills ◽  
...  
Keyword(s):  
Health Promotion ◽  
Controlled Trial ◽  
Health Promotion Program ◽  
Dental Disease ◽  
Oral Health Promotion ◽  
Australian Aboriginal ◽  
Disease Outcomes ◽  
Randomised Controlled ◽  
Aboriginal Children ◽  
Single Blind

scholarly journals Diet and anthropometry at 2 years of age following an oral health promotion programme for Australian Aboriginal children and their carers: a randomised controlled trial

2017 ◽  
Vol 118 (12) ◽  
pp. 1061-1069 ◽  
Author(s):  
Lisa G. Smithers ◽  
John Lynch ◽  
Joanne Hedges ◽  
Lisa M. Jamieson
Keyword(s):  
Health Promotion ◽  
Oral Health ◽  
Treatment Group ◽  
Randomised Controlled Trial ◽  
Controlled Trial ◽  
Control Group ◽  
Culturally Appropriate ◽  
Oral Health Promotion ◽  
Randomised Controlled ◽  
Aboriginal Children

AbstractThere are marked disparities between indigenous and non-indigenous children’s diets and oral health. Both diet and oral health are linked to longer-term health problems. We aimed to investigate whether a culturally appropriate multi-faceted oral health promotion intervention reduced Aboriginal children’s intake of sugars from discretionary foods at 2 years of age. We conducted a single-blind, parallel-arm randomised controlled trial involving women who were pregnant or had given birth to an Aboriginal child in the previous 6 weeks. The treatment group received anticipatory guidance, Motivational Interviewing, health and dental care for mothers during pregnancy and children at 6, 12 and 18 months. The control group received usual care. The key dietary outcome was the percent energy intake from sugars in discretionary foods (%EI), collected from up to three 24-h dietary recalls by trained research officers who were blind to intervention group. Secondary outcomes included intake of macronutrients, food groups, anthropometric z scores (weight, height, BMI and mid-upper arm circumference) and blood pressure. We enrolled 224 children to the treatment group and 230 to the control group. Intention-to-treat analyses showed that the %EI of sugars in discretionary foods was 1·6 % lower in the treatment group compared with control (95 % CI −3·4, 0·2). This culturally appropriate intervention at four time-points from pregnancy to 18 months resulted in small changes to 2-year-old Aboriginal children’s diets, which was insufficient to warrant broader implementation of the intervention. Further consultation with Aboriginal communities is necessary for understanding how to improve the diet and diet-related health outcomes of young Aboriginal children.

scholarly journals Treatment of scabies using a tea tree oil-based gel formulation in Australian Aboriginal children: protocol for a randomised controlled trial

BMJ Open ◽  
2018 ◽  
Vol 8 (5) ◽  
pp. e018507 ◽  
Author(s):  
Jackson Thomas ◽  
Rachel Davey ◽  
Gregory M Peterson ◽  
Christine Carson ◽  
Shelley F Walton ◽  
...  
Keyword(s):  
Randomised Controlled Trial ◽  
Controlled Trial ◽  
Tea Tree Oil ◽  
Tea Tree ◽  
Australian Aboriginal ◽  
Randomised Controlled ◽  
Aboriginal Children

scholarly journals 10-Valent pneumococcal non-typeable H. influenzae protein D conjugate vaccine (PHiD-CV10) versus 13-valent pneumococcal conjugate vaccine (PCV13) as a booster dose to broaden and strengthen protection from otitis media (PREVIX_BOOST) in Australian Aboriginal children: study protocol for a randomised controlled trial

BMJ Open ◽  
2020 ◽  
Vol 10 (5) ◽  
pp. e033511
Author(s):  
Victor M Oguoma ◽  
Nicole Wilson ◽  
Kim Mulholland ◽  
Mathuram Santosham ◽  
Paul Torzillo ◽  
...  
Keyword(s):  
Haemophilus Influenzae ◽  
Otitis Media ◽  
Conjugate Vaccine ◽  
Booster Dose ◽  
Controlled Trial ◽  
Australian Aboriginal ◽  
Department Of Health ◽  
Randomised Controlled ◽  
Antibody Levels ◽  
Aboriginal Children

IntroductionStreptococcus pneumoniae and non-typeable Haemophilus influenzae (NTHi) are major otitis media pathogens that densely co-colonise the nasopharynx and infect the middle ear of Australian Aboriginal infants from very early in life. Our co-primary hypotheses are that at 18 months of age infants receiving 10-valent pneumococcal Haemophilus influenzae protein D conjugate vaccine (PHiD-CV10) compared with those receiving 13-valent pneumococcal conjugate vaccine (PCV13) as a booster at 12 months of age will have higher antibody levels to Haemophilus influenzae protein D and that infants receiving PCV13 will have higher antibody levels to PCV13-only serotypes 3, 6A and 19A.Methods and analysesOur randomised controlled trial will enrol 270 Aboriginal children at 12 months of age to a booster dose of either PHiD-CV10 or PCV13. Children who completed the three-dose primary course schedules of PHiD-CV10 at 2, 4, 6 months of age; PCV13 at 2, 4, 6 months of age; or a combination schedule of PHiD-CV10 at 1, 2, 4 months of age plus PCV13 at 6 months of age are eligible. The co-primary assessor-blinded outcomes when the infants are 18 months of age are as follows: (a) IgG geometric mean concentration (GMC) and proportion with IgG ≥100 EU/mL for protein D, and (b) IgG GMC and the proportion with IgG ≥0.35 µg/mL for pneumococcal serotypes 3, 6A and 19A. Secondary immunogenicity comparisons of six primary and booster dose schedules of 10 shared serotypes at 18 months of age, nasopharyngeal carriage, all forms of otitis media, hearing loss and developmental milestones at 18, 24, 30 and 36 months of age will be reported.Ethics and disseminationEthics committees of NT Department of Health, Menzies, WA Department of Health and WA Aboriginal Health approved the study. Results will be presented to communities, at conferences and published in peer-reviewed journals.Trial registration numberNCT01735084.

Sign in / Sign up

Export Citation Format

Share Document