Determination of bisphenol analogues in food-contact plastics using diode array detector, charged aerosol detector and evaporative light-scattering detector

2019 ◽  
Vol 186 ◽  
pp. 109778 ◽  
Author(s):  
Huiyu Wang ◽  
Shanjun Song ◽  
Mingwu Shao ◽  
Yan Gao ◽  
Chen Yang ◽  
...  
Keyword(s):  
Light Scattering ◽  
Array Detector ◽  
Diode Array ◽  
Diode Array Detector ◽  
Evaporative Light Scattering Detector ◽  
Charged Aerosol ◽  
Bisphenol Analogues ◽  
Charged Aerosol Detector ◽  
Evaporative Light Scattering

scholarly journals Binary HPLC-Diode Array Detector and HPLC-Evaporative Light-Scattering Detector Fingerprints of Methanol Extracts from the Selected Sage (Salvia) Species

2011 ◽  
Vol 94 (1) ◽  
pp. 71-76 ◽  
Author(s):  
Mieczysław Sajewicz ◽  
Dorota Staszek ◽  
Łukasz Wojtal ◽  
Teresa Kowalska ◽  
Michał Ł Hajnos ◽  
...  
Keyword(s):  
Light Scattering ◽  
Array Detector ◽  
Diode Array ◽  
Diode Array Detector ◽  
Evaporative Light Scattering Detector ◽  
Methanol Extracts ◽  
Evaporative Light Scattering ◽  
Single Detector ◽  
Salvia Officinalis L ◽  
Binary Fingerprints

Abstract This study is focused on an important family of the sage (Salvia) species, with Salvia officinalis L. having a long-established position in European traditional medicine. Binary fingerprints (chromatographic profiles) of six different sage species were compared using HPLC coupled with two different detectors: the diode-array detector and the evaporative light-scattering detector. Advantages of using binary fingerprinting over single-detector fingerprinting are demonstrated and discussed, with selected examples. Experimental data are provided for a comparison of the chemical composition of sage samples originating from two harvesting seasons (2007 and 2008). A number of phytochemical standards (i.e., certain phenolic acids, flavonoids, and coumarin) were used that allowed identification and semiquantitative estimation of these particular compounds in the analyzed methanol extracts.

DETERMINATION OF CHLORHEXIDINE DIGLUCONATE IN DISINFECTANTS

2018 ◽  
Vol 61 (8) ◽  
pp. 4
Author(s):  
Sergey V. Andreev ◽  
Evgeny S. Belyaev ◽  
Anna O. Ivanova ◽  
Elvina A. Novikova ◽  
Anatoly A. Ishchenko
Keyword(s):  
Bromophenol Blue ◽  
Array Detector ◽  
Diode Array ◽  
Blue Color ◽  
Chlorhexidine Digluconate ◽  
Diode Array Detector ◽  
Charged Aerosol ◽  
Charged Aerosol Detector ◽  
Wide Range

Chlorhexidine digluconate has been widely used in lenticular compositions, skin antiseptics and other ready-to-use disinfectants. This is due to its low toxicity, as well as a wide range of antimicrobial effects. A commonly used method for the analysis of commercially available chlorhexidine digluconate (usually available as a 20% aqueous solution) is high-performance liquid chromatography. In this article, the main methods of analysis used to determine chlorhexidine digluconate in disinfectants and skin antiseptics are considered. A new simple technique for the determination of chlorhexidine digluconate in technical products and disinfectants based on acid-base titration in alcohol-ketone is developed. It is shown that in this medium hydrochloric acid interacts with two nitrogen atoms of the chlorhexidine digluconate molecule. The end point of the titration is established by the transition of the blue color to green in the presence of bromophenol blue. The range of measured concentrations is from 0.1 to 2.0 mass%. The relative error of the method is 2.5% with the confidence probability P = 0.95. A comparison of the diode array detector and the charged aerosol detector for the determination of chlorhexidine digluconate has been performed. It is shown that a charged aerosol detector can be used to analyze chlorhexidine digluconate in cases where it is difficult to analyze with an ultraviolet or diode array detector. However, the sensitivity of the detector of charged aerosols is significantly lower than that of the diode matrix, and the linearity range is smaller. All methods were tested on model samples, as well as on samples of disinfectants, skin antiseptics, soaps and wipes with antibacterial effect.

scholarly journals Determining High-Intensity Sweeteners in White Spirits Using an Ultrahigh Performance Liquid Chromatograph with a Photo-Diode Array Detector and Charged Aerosol Detector

Molecules ◽  
2019 ◽  
Vol 25 (1) ◽  
pp. 40 ◽  
Author(s):  
Kang Ma ◽  
Xiaojia Li ◽  
Yiwen Zhang ◽  
Fei Liu
Keyword(s):  
Correlation Coefficients ◽  
Array Detector ◽  
Diode Array ◽  
Diode Array Detector ◽  
Liquid Chromatograph ◽  
Limits Of Detection ◽  
Photo Diode ◽  
Charged Aerosol ◽  
Charged Aerosol Detector ◽  
Relative Standard

In China, white spirit is not only an alcoholic drink but also a cultural symbol. A novel and accurate method for simultaneously determining nine sweeteners (most authorized for use in China) in white spirits by ultrahigh performance liquid chromatography (UHPLC) with a photo-diode array detector (PDA) and charged aerosol detector (CAD) was developed. The sweeteners were acesulfame, alitame, aspartame, dulcin, neotame, neohesperidine dihydrochalcone, saccharin, sodium cyclamate, and sucralose. The sweeteners were separated within 16 min using a BEH C18 column and linear gradient-elution program. The optimized method allowed low concentrations (micrograms per gram) of sweeteners to be simultaneously detected. The CAD gave good linearities (correlation coefficients > 0.9936) for all analytes at concentrations of 0.5 to 50.0 μg/g. The limits of detection were 0.16 to 0.77 μg/g. Acesulfame, dulcin, neohesperidine dihydrochalcone, and saccharin were determined using the PDA detector, which gave correlation coefficients > 0.9994 and limits of detection of 0.16 to 0.22 μg/g. The recoveries were 95.1% to 104.9% and the relative standard deviations were 1.6% to 3.8%. The UHPLC-PDA-CAD method is more convenient and cheaper than LC-MS/MS methods. The method was successfully used in a major project called “Special Action against Counterfeit and Shoddy white spirits” and to monitor risks posed by white spirits in China.

scholarly journals Development of an LC-NMR System Using a Diode Array Detector and a Charged Aerosol Detector

2020 ◽  
Vol 69 (3) ◽  
pp. 151-155
Author(s):  
Yayoi KANBAYASHI ◽  
Yu TSUTSUMI ◽  
Toshimi MIZUKOSHI ◽  
Hideyuki YAMAGUCHI
Keyword(s):  
Array Detector ◽  
Diode Array ◽  
Diode Array Detector ◽  
Charged Aerosol ◽  
Charged Aerosol Detector
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