Bone health of patients with juvenile idiopathic arthritis: a comparison between dual-energy X-ray absorptiometry and digital X-ray radiogrammetry

2015 ◽  
Vol 84 (10) ◽  
pp. 1999-2003 ◽  
Author(s):  
Charlotte M. Nusman ◽  
Janneke Anink ◽  
Marieke H. Otten ◽  
Marion A.J. van Rossum ◽  
Rick R. van Rijn ◽  
...  
2018 ◽  
Vol 30 (4) ◽  
pp. 466-473 ◽  
Author(s):  
Ana Torres-Costoso ◽  
Dimitris Vlachopoulos ◽  
Esther Ubago-Guisado ◽  
Asunción Ferri-Morales ◽  
Iván Cavero-Redondo ◽  
...  

Purpose: The present study aims to investigate the association between dual-energy X-ray absorptiometry (DXA) and quantitative ultrasound (QUS) parameters and the intermethods agreement in active males. Methods: In this cross-sectional study, bone health (by DXA and calcaneal QUS), physical activity (by accelerometers), and anthropometrics measurements were assessed in 117 active adolescents (12–14 y old). Bivariate correlation coefficients were calculated to assess the relationships between DXA standard regions of interest and QUS parameters. Intraclass correlation coefficients and Bland–Altman plots were used to assess the level of agreement between bone mineral content regions derived from DXA and stiffness index. The measurements were z score transformed for comparison. Results: Most QUS parameters were positive and significantly correlated with DXA outcomes (stiffness index: r = .43–.52; broadband ultrasound attenuation: r = .50–.58; speed of sound: r = .25–.27) with the hip showing the highest correlations. Moreover, the present study found fair to good intraclass correlation coefficients of agreement (.60–.68) between DXA and QUS to assess bone health. The Bland–Altman analysis showed a limited percentage of outliers (3.2%–8.6%). Conclusion: QUS device could represent an acceptable alternative method to assess bone health in active adolescent males.


2018 ◽  
Vol 37 (2) ◽  
pp. 687-694 ◽  
Author(s):  
Esther Neelis ◽  
Noortje Rijnen ◽  
Johanna Sluimer ◽  
Joanne Olieman ◽  
Dimitris Rizopoulos ◽  
...  

2015 ◽  
Vol 86 (11) ◽  
pp. e4.4-e4
Author(s):  
James Bashford ◽  
Eli Silber

In order to better inform local clinical practice, we collected primary data from our local MS population. We addressed important aspects concerning relapse management, bone health, mental health, sphincter dysfunction, symptom burden, recognition of comorbidities and pharmacological treatment. An emphasis was placed on discovering the extent of patient satisfaction with the local service.An 11-page patient questionnaire was distributed to consecutive consenting patients attending the MS clinic. A supplemental questionnaire was provided to those patients on regular natalizumab therapy. In total, 92 full and 22 natalizumab questionnaires were completed.Two particular areas highlighted for improvement with regards to patient management and patient education were bone and mental health:1. Only 26% of respondents confirmed having had a dual-energy X-ray absorptiometry (DEXA) scan. When asked if reduced ability in MS is an important risk factor for osteoporosis, only 44/92 patients confirmed they thought this was true.2. In the last year, 41% and 58% of respondents have suffered from depression and anxiety, respectively. Despite this, only a third of these patients received any treatment (pharmacological or non-pharmacological) for anxiety, depression or both.Encouragingly, 95% of those surveyed would recommend our MS service to a friend or family member.


Cureus ◽  
2019 ◽  
Author(s):  
Farah Anwar ◽  
Hiba Iftekhar ◽  
Tasneem Taher ◽  
Syeda K Kazmi ◽  
Fatima Z Rehman ◽  
...  

2020 ◽  
Vol 50 (12) ◽  
pp. 1781-1787
Author(s):  
David J. Fennimore ◽  
Maria Digby ◽  
Margaret Paggiosi ◽  
Paul Arundel ◽  
Nick J. Bishop ◽  
...  

Abstract Bone health in children with osteogenesis imperfecta is monitored using radiographs and dual-energy X-ray absorptiometry, which have limitations. High-resolution peripheral quantitative CT can non-invasively derive bone microarchitectural data. Children with severe osteogenesis imperfecta have fragile deformed bones, and positioning for this scan can be difficult. We assessed the feasibility of high-resolution peripheral quantitative CT in nine children aged 9–15 years with osteogenesis imperfecta and compared results with dual-energy X-ray absorptiometry and with healthy controls. All nine recruited children were successfully scanned and showed no preference for either modality. It therefore appears feasible to perform high-resolution peripheral quantitative CT in children with osteogenesis imperfecta aged 9 years and older. Future studies should focus on understanding the clinical implications of the technology in this patient cohort.


2013 ◽  
Vol 81 (2) ◽  
pp. 126-132 ◽  
Author(s):  
Soumya Dey ◽  
Afsana Jahan ◽  
Tribhuvan Pal Yadav ◽  
Devesh Kumar Bhagwani ◽  
Namrita Sachdev

2018 ◽  
Vol 49 (3) ◽  
pp. 372-378 ◽  
Author(s):  
Khalaf Alshamrani ◽  
Fabrizio Messina ◽  
Nick Bishop ◽  
Amaka C. Offiah

BMJ Open ◽  
2021 ◽  
Vol 11 (12) ◽  
pp. e051021
Author(s):  
Amar Rangan ◽  
Stephen P Tuck ◽  
Paul D Scott ◽  
Lucksy Kottam ◽  
Maya Jafari ◽  
...  

ObjectivesTo evaluate a method of quantitative X-ray (QXR) for obtaining bone health information from standard radiographs aimed at identifying early signs of osteoporosis to enable improved referral and treatment. This QXR measurement is performed by postexposure analysis of standard radiographs, meaning bone health data can be acquired opportunistically, alongside routine imaging.DesignThe relationship between QXR and dual energy X-ray absorptiometry (DEXA) was demonstrated with a phantom study. A prospective clinical study was conducted to establish areal bone mineral density (aBMD) prediction model and a risk prediction model of a non-normal DEXA outcome. This was then extrapolated to a larger patient group with DEXA referral data.SettingSecondary care National Health Service Hospital.Participants126 consenting adult patients from a DEXA clinic.InterventionsAll participants underwent a DEXA scan to determine BMD at the lumbar spine (L2–L4) and both hips. An additional Antero-Posterior pelvis X-ray on a Siemens Ysio, fixed digital radiograph system was performed for the study.OutcomePerformance of QXR as a risk predictor for non-normal (osteoporotic) BMD.ResultsInterim clinical study data from 78 patients confirmed a receiver operator curve (area under the ROC curve) of 0.893 (95% CI 0.843 to 0.942) for a risk prediction model of non-normal DEXA outcome. Extrapolation of these results to a larger patient group of 11 029 patients indicated a positive predictive value of 0.98 (sensitivity of 0.8) for a population of patients referred to DEXA under current clinical referral criteria.ConclusionsThis study confirms that the novel QXR method provides accurate prediction of a DEXA outcome.Trial registration numberISRCTN98160454; Pre-results.


Sign in / Sign up

Export Citation Format

Share Document