scholarly journals Assessment of non-steroidal anti-inflammatory drugs from selected wastewater treatment plants of Southwestern India

2021 ◽  
Vol 7 ◽  
pp. 43-51
Author(s):  
Yerabham Praveenkumarreddy ◽  
Krishnamoorthi Vimalkumar ◽  
Babu Rajendran Ramaswamy ◽  
Virendra Kumar ◽  
Rakesh Kumar Singhal ◽  
...  
2021 ◽  
Vol 25 (3) ◽  
pp. 330-340
Author(s):  
A.S. Ajibola ◽  
A.O. Adebiyi ◽  
D.O. Nwaeke ◽  
F.O. Ajibola ◽  
G.O. Adewuyi

Despite the frequent detection of non-steroidal anti-inflammatory drugs (NSAIDs) worldwide in the aquatic environment, there is currently a paucity of studies from Africa, including Nigeria, on the occurrence and potential ecological risks of two commonly used NSAIDs diclofenac and ibuprofen in wastewater and effluent receiving water. In this work, diclofenac and ibuprofen were determined in wastewater from three wastewater treatment plants (WWTPs) and effluent receiving water in South-Western Nigeria. Instrumental analysis was performed by high-performance liquid chromatography. Ecological risk was assessed for four trophic levels: fish, daphnia, algae and bacteria. The method quality parameters were satisfactory for the accurate determination of target NSAIDs in wastewater and effluent receiving water. Maximum concentrations of diclofenac and ibuprofen in wastewater were 166.1 µg L-1 (UCH influent) and 62.0 µg L-1 (Ijaiye effluent), respectively. Ibuprofen posed high risk to fish in all effluent and effluent receiving water samples. Bacteriawere the most sensitive organisms to the presence of diclofenac while fish was the most sensitive to ibuprofen. To the best of our knowledge, this is the first report on the occurrence and ecological risk assessment of diclofenac and ibuprofen residues in wastewater from Nigerian municipal and hospital WWTPs. More efficient wastewater treatment processes and technologies are recommended for the investigated WWTPs to reduce the discharge of target NSAIDs and other pharmaceuticals into the Nigerian aquatic environment. Keywords: Non-steroidal anti-inflammatory drugs, wastewater, ecological risk assessment, Nigeria


2002 ◽  
Vol 46 (3) ◽  
pp. 73-80 ◽  
Author(s):  
J.E. Drewes ◽  
T. Heberer ◽  
K. Reddersen

The scope of this study was directed to examine different wastewater treatment technologies (activated sludge, trickling filter, nanofiltration, reverse osmosis) at full-scale facilities in Arizona and California leading to indirect potable reuse and their capability to remove pharmaceuticals. Additionally, the fate of selected pharmaceuticals was studied during soil-aquifer treatment (SAT) at sites where secondary and tertiary treated effluents are used for subsequent groundwater recharge. Facilities employing longer detention times during treatment (nitrifying and denitrifying plants) showed significant lower effluent concentration for analgesic drugs as compared to trickling filter or activated sludge facilities applying shorter detention times. A similar trend was observed for the lipid regulator gemfibrozil, which was significantly removed in denitrified effluents, whereas a trickling filter treated effluent exhibited concentration of 1,235 ng/L. Antiepileptic drugs, such as carbamazepine and primidone, showed no dependency on the wastewater treatment applied. None of the investigated drugs was detected in tertiary treated effluents after nanofiltration or reverse osmosis. After SAT, analgesic/anti-inflammatory drugs were efficiently removed after retention times of less than 6 months and remaining concentrations were near or below the detection limit of the analytical method. A high potential for biodegradation was also observed for anti-inflammatory drugs in groundwater recharge systems. The antiepileptics carbamazepine and primidone represented the most dominant of all investigated drugs in well treated domestic effluents (nitrifying/denitrifying plants). Removal of carbamazepine and primidone did not seem to occur during travel times of more than 6 years in the subsurface.


2014 ◽  
Vol 14 (3) ◽  
pp. 63-74 ◽  
Author(s):  
Ewelina Płuciennik-Koropczuk

Abstract Increased production and consumption of drugs influences the pollution pharmaceuticals. Recent years have seen a significant increase in the consumption of non-prescription medicines, among which, are a large group of non-steroidal anti-inflammatory drugs (NSAIDs). Research conducted in Poland and abroad showed the presence of NSAIDs, both in treated wastewater in surface waters and drinking waters. One of the most frequently detected drugs in the environment is diclofenac, belongs to NSAID. Its concentration in surface waters range from 9 to 3363 ng/L. Traditional wastewater treatment plants are not specialized enough in removing the pharmaceuticals and their metabolites, and with purified wastewater are introduced into surface waters. Diclofenac concentrations in treated wastewater range from 0.29 to 2.5 μg/L, the average removal efficiency is about 40%.


2010 ◽  
Vol 62 (12) ◽  
pp. 2862-2871 ◽  
Author(s):  
R. Salgado ◽  
J. P. Noronha ◽  
A. Oehmen ◽  
G. Carvalho ◽  
M. A. M. Reis

Pharmaceuticals and personal care products (PPCPs) are becoming increasingly recognised as important micropollutants to be monitored in wastewater treatment plants (WWTPs), since WWTP effluents represent an important point source to natural aquatic systems. In this study, the abundance of 65 PPCPs was analysed in 5 Portuguese WWTPs during the spring and autumn. Due to the fact that analytical approaches normally used to quantify the abundance of these compounds are labour intensive and require various specific procedures, this study proposes a set of simplified analytical methods for the quantification of pharmaceutically active compounds (PhACs) and polycyclic musks in liquid and sludge samples. The analytical methods were validated using influent wastewater matrices, showing comparable limits of detection and quantification as literature values for most PPCPs, with the exception of the estrogenic compounds. The PhAC concentrations detected in the WWTP survey were in the range of 0.050–100 μg L−1 in the influent and up to 50 μg L−1 in the effluent, where the non-steroidal anti-inflammatory drugs (NSAIDs) were the most abundant and frequently detected group. Some musks were detected up to 11.5 μg L−1 in the influent and 0.9 μg L−1 in the effluent, and adsorbed in the sludge up to 22.6 μg g−1.


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