Fosfomycin Trometamol for the Prevention of Infectious Complications After Prostate Biopsy: A Consensus Statement by an International Multidisciplinary Group

2021 ◽  
Author(s):  
Truls E. Bjerklund Johansen ◽  
Ekaterina Kulchavenya ◽  
Gretchen M. Lentz ◽  
David M. Livermore ◽  
J. Curtis Nickel ◽  
...  
Keyword(s):  
Prostate Biopsy ◽  
Consensus Statement ◽  
Infectious Complications ◽  
Fosfomycin Trometamol ◽  
Multidisciplinary Group

scholarly journals Combined antibiotic prophylaxis of infectious complications of prostate biopsy

2021 ◽  
Vol 22 (3) ◽  
pp. 49-55
Author(s):  
N. A. Grigoryev ◽  
I. I. Abdullin ◽  
B. R. Gvasalia ◽  
A. V. Loginov ◽  
E. V. Zhilyaev
Keyword(s):  
Antibiotic Prophylaxis ◽  
Prostate Biopsy ◽  
Antimicrobial Prophylaxis ◽  
Average Length ◽  
Infectious Complications ◽  
Fluoroquinolone Resistance ◽  
Single Shot ◽  
Average Length Of Stay ◽  
Transrectal Prostate Biopsy ◽  
Fosfomycin Trometamol

Introduction. Biopsy of prostate is a routine urologic procedure. Nevertheless the frequency of infectious-inflammatory complications remain high, despite the recommended antibiotic prophylaxis schemes.Purpose. The evaluation of effectiveness and safety of combined antimicrobial prophylaxis: fosfomycin trometamol and fluoroquinolones of 3rd generation.Materials and methods. Our clinical study included 80 patients who underwent prostate biopsy were divided into 2 groups. The first group of 40 patients received routine prophylaxis: levofloxacin 500 mg 6 h before the biopsy and 500 mg per day during 4 days after biopsy. The second group of 40 patients, along with standard prophylaxis as in the first group, additionally after biopsy received fosfomycin trometamol 3 gr single-shot.Results. In the first group, infectious and inflammatory complications occurred in 8 (20 %) patients, 12.5 % of patients from the first group were hospitalized for parenteral antibiotic therapy. The average length of stay in hospital was 3.4 ± 1.45 days. In all cases, in the first group of patients, Escherichia coli was detected, in 70 % of cases fluoroquinolone-resistant strain of the bacterium was received. In the second group of patients no hospitalization was required. One (2.5 %) patient out of forty from this group showed signs of urinary tract infection, which was not accompanied by an increase of body temperature, as well as changes in blood and urine tests.Conclusions. Our results show good effectiveness and safety of combined antibiotic prophylaxis for transrectal prostate biopsy. Since fluoroquinolone resistance grows, it is necessary to introduce alternative schemes, as well as monitoring of nosocomial infection and controlling of antimicrobial therapy.

scholarly journals MP57-12 THE IMPACT OF INFECTIOUS COMPLICATIONS AFTER PROSTATE BIOPSY ON RADICAL PROSTATECTOMY SURGICAL OUTCOMES: A POPULATION-BASED ANALYSIS

2016 ◽  
Vol 195 (4S) ◽  
Author(s):  
Daniel Olvera-Posada ◽  
Blayne Welk ◽  
J. Andrew McClure ◽  
Jennifer Winick-Ng ◽  
Jonathan I. Izawa ◽  
...  
Keyword(s):  
Radical Prostatectomy ◽  
Prostate Biopsy ◽  
Surgical Outcomes ◽  
Population Based ◽  
Infectious Complications ◽  
The Impact

Rectal E. coli above ciprofloxacin ECOFF associate with infectious complications following prostate biopsy

2018 ◽  
Vol 37 (6) ◽  
pp. 1055-1060 ◽  
Author(s):  
Inari Kalalahti ◽  
Kaisa Huotari ◽  
Kanerva Lahdensuo ◽  
Eveliina Tarkka ◽  
Henrikki Santti ◽  
...  
Keyword(s):  
Prostate Biopsy ◽  
Infectious Complications ◽  
E Coli

scholarly journals Impact of Rectal Swabs on Infectious Complications after Transrectal Prostate Biopsy

2016 ◽  
Vol 97 (3) ◽  
pp. 340-346 ◽  
Author(s):  
Carlos Gustavo Trujillo ◽  
Mauricio Plata ◽  
Juan Ignacio Caicedo ◽  
Juan Guillermo Cataño Cataño ◽  
Angela Marcela Mariño Alvarez ◽  
...  
Keyword(s):  
Prostate Biopsy ◽  
Infectious Complications ◽  
Rectal Swabs ◽  
Transrectal Prostate Biopsy

Infectious complications of prostate biopsy: winning battles but not war

2020 ◽  
Vol 38 (11) ◽  
pp. 2743-2753 ◽  
Author(s):  
Okan Derin ◽  
Limírio Fonseca ◽  
Rafael Sanchez-Salas ◽  
Matthew J. Roberts
Keyword(s):  
Prostate Biopsy ◽  
Infectious Complications

scholarly journals Complications of Prostate Biopsy: A Prospective, Single-institution Study

2020 ◽  
pp. 271-279
Author(s):  
Colette M. Antoine ◽  
Belinda F. Morrison ◽  
Michael E. Brooks
Keyword(s):  
Urinary Tract ◽  
Urinary Retention ◽  
Prostate Biopsy ◽  
Public Hospital ◽  
Retention Rate ◽  
Tertiary Care ◽  
Transrectal Ultrasound ◽  
Final Analysis ◽  
Infectious Complications ◽  
Prostate Biopsies

Aims:  This study aimed to determine the prevalence rates of transrectal ultrasound-guided prostate biopsy-related complications among patients receiving treatment at the large tertiary-care urology clinic of Kingston Public Hospital (KPH), Jamaica. Study Design: Prospective cohort study. Place and Duration of Study: Kingston Public Hospital (KPH), Jamaica from July 2018 to April 2019. Methodology: Our study population included men who underwent prostate biopsy at KPH. Data on demographics and clinical characteristics were collected using purpose-designed questionnaires from consenting patients who underwent prostate biopsy during the stated period. Patients were then followed up for complications 30 days post biopsy. Details regarding hospitalization due to biopsy-related complications were obtained from the medical records. Results: Data from 185 men were included in the final analysis. Among the patients biopsied, 49% were diagnosed with prostate cancer, while 72% experienced at least one complication, mainly non-infectious complications such as hematuria (46%), lower urinary tract symptoms (24%), rectal bleeding (23%), hematospermia (9%), and urinary retention (16%). Overall, a 15% risk of developing infectious complications was observed, with 9% experiencing fever and 3% experiencing both urinary tract infection and epididymo-orchitis. Our data showed a 6% hospitalization rate within 30 days, with all available records suggesting infectious complications. One death from a prostatic abscess was noted. The present study showed that most prostate biopsy complications were minor. Moreover, although bleeding and infectious complications as well as hospitalization rates were consistent with those reported in larger series, our population experienced a slightly higher mortality and urinary retention rate. Conclusion: Overall, our results showed that prostate biopsies performed within our institution are generally safe and well tolerated. Nonetheless, further studies are needed to determine whether morbidity of the procedure remains acceptable.

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