Colorectal cancer survivors’ willingness to participate in a hypothetical clinical trial of Korean medicine: A cross-sectional study

2020 ◽  
Vol 33 ◽  
pp. 101033
Author(s):  
Yown Hwangbo ◽  
Gyung Mo Son ◽  
Kyung Hee Kim ◽  
Myeong Sook Kwon ◽  
Kun Hyung Kim
Keyword(s):  
Colorectal Cancer ◽  
Clinical Trial ◽  
Cancer Survivors ◽  
Cross Sectional Study ◽  
Willingness To Participate ◽  
Sectional Study ◽  
Cross Sectional ◽  
Korean Medicine ◽  
Colorectal Cancer Survivors

scholarly journals Colorectal Cancer Survivors Suffering From Sensory Chemotherapy-Induced Peripheral Neuropathy Are Not a Homogenous Group: Secondary Analysis of Patients’ Profiles With Oxaliplatin-Induced Peripheral Neuropathy

2021 ◽  
Vol 12 ◽  
Author(s):  
Nicolas Kerckhove ◽  
Marie Selvy ◽  
Céline Lambert ◽  
Coralie Gonneau ◽  
Gabrielle Feydel ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Peripheral Neuropathy ◽  
Cancer Survivors ◽  
Depressive Disorders ◽  
Secondary Analysis ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Homogenous Group ◽  
Colorectal Cancer Survivors ◽  
Cluster 2

Oxaliplatin, a pivotal drug in the management of colorectal cancer, causes chemotherapy-induced peripheral neuropathy (CIPN) in a third of cancer survivors. Based on a previous cross-sectional study assessing oxaliplatin-related sensory CIPN in colorectal cancer survivors, a secondary analysis was designed to explore the possibility that different clusters of patients may co-exist among a cohort of patients with oxaliplatin-related CIPN. Other objectives were to characterize these clusters considering CIPN severity, anxiety, depression, health-related quality of life (HRQOL), patients’ characteristics and oxaliplatin treatments. Among the 96 patients analyzed, three clusters were identified (cluster 1: 52, cluster 2: 34, and cluster 3: 10 patients). Clusters were significantly different according to CIPN severity and the proportion of neuropathic pain (cluster 1: low, cluster 2: intermediate, and cluster 3: high). Anxiety, depressive disorders and HRQOL alteration were lower in cluster 1 in comparison to clusters 2 and 3, but not different between clusters 2 and 3. This study underlines that patients with CIPN are not a homogenous group, and that CIPN severity is associated with psychological distress and a decline of HRQOL. Further studies are needed to explore the relation between clusters and CIPN management.

scholarly journals Self-Management of Oxaliplatin-Related Peripheral Neuropathy in Colorectal Cancer Survivors

2013 ◽  
Vol 2013 ◽  
pp. 1-7 ◽  
Author(s):  
Cindy Tofthagen ◽  
Laura Gonzalez ◽  
Constance Visovsky ◽  
Alex Akers
Keyword(s):  
Colorectal Cancer ◽  
Peripheral Neuropathy ◽  
Cancer Survivors ◽  
Nutritional Supplement ◽  
Cross Sectional Study ◽  
Self Management ◽  
Painful Neuropathy ◽  
Cross Sectional ◽  
Colorectal Cancer Survivors ◽  
Temporary Relief

Purpose. The purpose of this study was to evaluate medications that cancer survivors with oxaliplatin-induced peripheral neuropathy take to control neuropathic symptom, and to explore self-management techniques used at home to provide temporary relief of painful neuropathy. This was a mixed methods, descriptive, cross-sectional study using self-reported data from colorectal cancer survivors previously treated with oxaliplatin. We analyzed demographic and medication data obtained from participants, along with written comments from an open-ended question regarding methods participants had tried to self-manage symptoms of neuropathy. Results. Twenty-nine percent of the sample reported taking some type of nutritional supplement with potential neuroprotective qualities. Opioids were being taken by 10% of the sample, and nonsteroidal anti-inflammatory and over-the-counter medications were taken by 15% of participants. Twelve percent of participants were taking antidepressants and 10% were taking anticonvulsants, primarily gabapentin. Recurrent themes for nonpharmacologic treatment included avoiding the cold/keeping warm, keeping moving, massaging or rubbing the affected area, and living with it. Conclusions. Patients treated with oxaliplatin for colorectal cancer utilize a variety of traditional pharmacologic agents and nutritional supplements in an effort to self-manage neuropathic symptoms. Patients also employ a variety of home-based therapies to provide temporary relief of peripheral neuropathy symptoms.

scholarly journals Knowledge, training and willingness to perform bystander cardiopulmonary resuscitation among university students in Chongqing, China: a cross-sectional study

BMJ Open ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. e046694
Author(s):  
Jiani Mao ◽  
Feng Chen ◽  
Dianguo Xing ◽  
Huixian Zhou ◽  
Ling Jia ◽  
...  
Keyword(s):  
College Students ◽  
Cardiopulmonary Resuscitation ◽  
Cross Sectional Study ◽  
Average Score ◽  
Willingness To Participate ◽  
Sectional Study ◽  
Cross Sectional ◽  
Bystander Cpr ◽  
Secondary Outcomes ◽  
Cpr Training

ObjectiveTo evaluate knowledge of cardiopulmonary resuscitation (CPR) among Chinese college students and their attitude towards participating in CPR training and willingness to perform bystander CPR.DesignA cross-sectional study.ParticipantsA total of 1128 college students were selected through a multistage stratified random sampling method from 12 universities in Chongqing, China.Primary and secondary outcomesPrimary outcomes included CPR knowledge and willingness to participate in training and perform bystander CPR; secondary outcomes included CPR training experience and obstacles to training and performing CPR.ResultsThe average score on CPR knowledge was 2.078 (±1.342). Only 45.5% of the respondents were willing to participate in CPR training. Women, respondents who were postgraduate or above, with liberal arts as major and with high CPR knowledge level were more willing to participate in CPR training. A total of 47.2% of the respondents were willing to provide simple assistance, such as checking the consciousness and breathing of the patient and dialling 120 (medical emergency call). Only 34.1% indicated their willingness to perform bystander CPR on strangers. Perceived behavioural control, behavioural attitudes and subjective norms are positive predictors of willingness to provide bystander CPR.ConclusionsCPR knowledge and training rate were low among Chongqing college students. Willingness to participate in training and perform bystander CPR was also low. Improving legislation, strengthening training programmes, incorporating CPR training into the school curriculum and reshaping the social and public culture of offering timely help to those in need are recommended strategies to improve bystander CPR performance.

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