scholarly journals P.0404 Rapid antidepressant response to first-line selective serotonin reuptake inhibitors in post-COVID-19 depression

2021 ◽  
Vol 53 ◽  
pp. S292-S293
Author(s):  
M.G. Mazza ◽  
M. Palladini ◽  
R. Zanardi ◽  
F. Benedetti
2020 ◽  
Vol 8 (1) ◽  
pp. 96-103
Author(s):  
Fatimah Azzahra ◽  
Rasmi Zakiah Oktarlina ◽  
High Boy Karumulborg Hutasoit

ABSTRAK Ansietas merupakan perasaan difus, yang sangat tidak menyenangkan dan tidak menentu tentang sesuatu yang akan terjadi. Menurut WHO, jumlah populasi global yang menderita ansietas pada tahun 2017 diperkirakan mencapai 3.8%. Estimasi total dari jumlah individu yang menderita ansietas di dunia adalah 284 juta orang. Hal ini menunjukkan peningkatan yang cukup tinggi dari tahun 2005 yakni sekitar 15.1%. Manifestasi klinis dari ansietas berbeda tergantung pada bentuk gangguannya, tetapi tanda dan gejala umum dari ansietas memeiliki karakteristik yang terdiri dari dua komponen yaitu fisik dan emosional yang memengaruhi proses kognitif seseorang. Pengobatan ansietas dapat menggunakan obat – obatan antiansietas, psikoterapi, ataupun keduanya. Lini pertama dari farmakoterapi ansietas adalah Selective Serotonin Reuptake Inhibitors (SSRIs) yang biasanya digunakan sebagai antidepresi. SSRIs dipilih sebagai lini pertama karena memiliki efek samping yang lebih rendah dibandingkan obat golongan lainnya. Terdapat pengaruh jenis kelamin terhadap efikasi antiansietas yang berguna terhadap pemilihan antiansietas.  Kata Kunci : Ansietas, Antiansietas, Farmakoterapi, Pengobatan   ABSTRACT Anxiety is a diffuse feeling, which is very unpleasant and uncertain about something that will happen. According to WHO, the total global population suffering from anxiety in 2017 is estimated to reach 3.8%. The total estimated number of people living with anxiety in the world is 284 million people. This shows a fairly high increase from 2005 which was around 15.1%. Clinical manifestations of anxiety is different depending on the form of the disorder, but the general signs and symptoms of anxiety have characteristics that consist of two components, that is physical and emotional that affect someone cognitive processes. The treatment of anxiety can using drugs, psychotherapy, or both. The first line of pharmacotherapy for anxiety is Selective Serotonin Reuptake Inhibitors (SSRIs), which are usually used as antidepressants. SSRIs were chosen as first-line because they have lower side effects than other class of drugs. There is an effect of sex on the efficacy of antianxiety that is useful for selection of the antianxiety.  Keywords : Anxiety, Antianxiety, Pharmacotherapy, Treatment


2014 ◽  
pp. 29-31
Author(s):  
Seshadri Sekhar Chatterjee ◽  
Arnab Maji ◽  
Nitu Mallik

SSRI are the widely prescribed first line drugs for depression and as depression very commonly presents with insomnia SSRI are good at improving the sleep problems also. But though rare the occurrence of sleep related side effects like bruxism,it may cause significant distress and cause of nonadherence which easily may be overlooked. In this case we report a case of Paroxetine induced bruxism and subsequently treated with withdrawing the drug and buspirone. Though the aetiology of such bruxism remained unclear, the imbalances in dopaminergic and serotonergic activities in the central nervous system is mostly implicated.Key Words : Bruxism, Escitalopram, Parafunctional activity, Selective Serotonin Reuptake Inhibitors


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