Long-acting injectable aripiprazole. Clinical experience in a case series

2016 ◽  
Vol 33 (S1) ◽  
pp. S614-S614
Author(s):  
J.M. Hernández Sánchez ◽  
M.C. Cancino Botello ◽  
M.F. Molina López ◽  
D. Peña Serrano ◽  
M. Machado Vera

IntroductionThe use of long-acting injectable antipsychotics is useful in patients with low therapeutic compliance.ObjectiveTo present the demographic and clinical data of a case series in which long-acting injectable aripiprazole has been prescribed in an ambulatory Mental Health Center.MethodsSystematic review of the related literature and clinical history of patients in which long-acting injectable aripiprazole had been prescribed from January to March 2015 in a Mental Health Center.ResultsWe found 10 patients, whose diagnosis were schizophrenia (4), non-specified psychosis (2), personality disorder (1), bipolar disorder (1), schizoaffective disorder (2), of whom 7 were men and 3 women, with a mean age of 43.8 years old. The mean of years since diagnosis was 15.1 years. In 7 patients, we found concomitant treatment with another antipsychotic agent (low dose quetiapine in all of them); antidepressants in 1 patient, benzodiazepines in 6; mood stabiliser in 5 and biperidene in 1. In relation to previous antipsychotic drugs, we found: aripiprazole 15 mg/day oral (4); long-acting injectable paliperdidone 150 mg/28 days (2) paliperdone 6 mg/day oral (1); combination of paliperidone 6 mg/day oral plus olanzapine 5 mg/day oral (1). Only 4 patients had used long-acting injectable drugs previously in their lifetime. The reason of having initiated treatment with long-acting injectable aripiprazole was sexual disturbance (3); lack of compliance (4); clinical inestability (2) and motor side effects (1).ConclusionsIn our series, we can observe a chronic patient profile, predominantly men with diagnosis of psychotic spectrum.Disclosure of interestThe authors have not supplied their declaration of competing interest.

2016 ◽  
Vol 33 (S1) ◽  
pp. S642-S642
Author(s):  
A. Uría de los Ojos ◽  
J. Ballesteros López ◽  
P. Rico García ◽  
A.B. González Palacios ◽  
C. Domínguez García

IntroductionMindfulness is defined as the ability of paying attention to the present moment with intentionality, moment to moment without making judgments of value.ObjectivesTo describe the effectiveness of group therapy performed in our mental health center according to the results in the SOFI scale of patients. This scale is designed to assess different qualities, which evolve through training in meditation practice based on mindfulness.MethodsGroup therapy consisted of 12 weekly sessions of an hour and a half. A total of 11 patients, 7 of which having completed therapy. The questionnaires were answered in the first and final session of therapy.ResultsThe questionnaire items were divided before and after treatment, into four categories with the following results: positive (friendly, happy, acceptance, compassion) to himself: 1.86 (0.54)/2.75 (0.78) and to others 3.57 (0.86)/3.89 (0.54); negative (hate, angry, cruel, bad) to himself: 2.92 (0.54)/2 (0.23); and to others: 2.28 (0.41)/1.96 (0.36)ConclusionsIn keeping with similar studies, the scale shows effectiveness of therapy in all sets of items, highlighting the variation of the aspects related to himself.Disclosure of interestThe authors have not supplied their declaration of competing interest.


2002 ◽  
Vol 15 (1) ◽  
pp. 29-39 ◽  
Author(s):  
Matthew J. Chinman ◽  
Janis Symanski‐Tondora ◽  
Avon Johnson ◽  
Larry Davidson

2017 ◽  
Vol 41 (S1) ◽  
pp. S424-S425
Author(s):  
L. Niell ◽  
J. Rodríguez ◽  
R.A. Baena ◽  
I. Alberdi-Paramo ◽  
G. Montero ◽  
...  

AimsObtain and analyze information on treatment guidelines, with particular emphasis on the use of antipsychotics, in patients diagnosed with bipolar disorder I and bipolar disorder II who are treated at a mental health center in a district of Madrid (Spain) under the conditions of habitual clinical practice.Then, compare with recently published literature.MethodsWe performed a descriptive study of a sample of 100 patients diagnosed with bipolar disorder (type I and type II) at any stage of the disease who receive regular treatment in a mental health center in a district of Madrid. Information regarding the treatment used, especially the use of antipsychotics (either in a single therapy or in combination with other drugs such as mood stabilizers, antidepressants, hypnotics or anxiolytics), was collected retrospectively from the data obtained from the medical record.ResultsNinety-four percent of patients are taking mood stabilizer treatment (68% lithium, 24% valproate, 1% and 1% carbamazepine and lamotrigine). Four percent take lithium and valproate in combination. Forty-eight percent of patients are taking some antipsychotic (atypical about 90%). Of these, only 10% in injectable form, and 5% take both oral and injectable antipsychotics.ConclusionsThe diminished use of injectable antipsychotics, well below recent publications, draws the attention. You can probably explain this low proportion of injectable medication because we are generally dealing with stable patients with a long-term disorder.Disclosure of interestThe authors have not supplied their declaration of competing interest.


2016 ◽  
Vol 33 (S1) ◽  
pp. S314-S314
Author(s):  
M.R. Raposo ◽  
V. Ivanov ◽  
J.B. Murcia ◽  
M.D. Piqueras ◽  
I. Martínez ◽  
...  

IntroductionCocaine use is prevalent in mental health consultations in both sexes. However, in men and women there are differences in the frequency of use of substances and on the employment situation.ObjectivesShow the differences for the use of cocaine and employment status of men and women, in a sample of patients followed at the Mental Health Center in Drug Dependency Unit.Material and methodsWe conducted a cross-sectional study and analyze the differences according to sex for cocaine use and the employment situation, in a sample of patients who are undergoing treatment at the Mental Health Center for a year diagnosed with dual pathology.ResultsIn men in active employment status, the percentage of cocaine use is 19.5% and if we compare with women in the same job situation, the percentage of cocaine use is 0%.Men who are unemployed use more cocaine than women in the same job situation. For retirees, the highest percentage of cocaine is found in women.Hundred percent of women use cocaine by sniffing. Men use different ways of cocaine consume.Snorted way 67.7%, 14.9% smoked and snorted, smoked 8% and 2.3% intravenous.ConclusionMen use cocaine more frequently unemployed while women do more it often being retired.The route most used cocaine consume in both sexes is snorted.Disclosure of interestThe authors have not supplied their declaration of competing interest.


2012 ◽  
Vol 73 (04) ◽  
pp. 513-517 ◽  
Author(s):  
Neil Krishan Aggarwal ◽  
Robert A. Rosenheck ◽  
Scott W. Woods ◽  
Michael J. Sernyak

2017 ◽  
Vol 41 (S1) ◽  
pp. s791-s792
Author(s):  
G. Fucci ◽  
N. Ratti ◽  
R. Ignarra

The identification of the early signs of crisis is globally considered one of the fundamental elements in the illness management practice of the psychiatric user. For this reason the mental health center of the city of Ravenna wanted to offer a personalized questionnaire to a 15 random-selected users and their families, with the aim of evaluating and analyzing the alarm signals in the participant's perception. The questionnaire has been created on the basis of other tests in the literature. It is divided in two parts, a “symptomatic”, related to the early signs of crisis, and an “environmental”, focalized on the potentially stressing situations for the individual. The administration took place within the individual and the family talks at the center. This project was implemented not only as a psycho-educational activity for the users and their family's, but also to amplify the knowledge of the staff on these signs. The results have shown how often there are points of difference in the perceptions of the early signs of crisis of the users and their families and it is believed this could turn out to be an important factor to be worked on within the projects of psycho-education of the mental health center.Disclosure of interestThe authors have not supplied their declaration of competing interest.


2016 ◽  
Vol 33 (S1) ◽  
pp. S314-S314
Author(s):  
M.R. Raposo ◽  
V. Ivanov ◽  
I. Martínez ◽  
J.B. Murcia ◽  
A.L. González ◽  
...  

IntroductionThe most common psychiatric disorders associated with substance use in patients with dual diagnosis, personality disorders are followed by schizophrenic disorder. Among the substances used in patients with dual diagnosis, stands cocaine, followed by cannabis and alcohol.ObjectivesEvaluate the differences in the frequency of sex for cocaine and cannabis consumed in a sample of patients undergoing follow Mental-Health Center for Drug Dependency Unit.Material and methodWe conducted a cross-sectional study and analyze the differences by gender for the frequency and pattern of cocaine and cannabis, in a sample of patients in treatment at the Mental-Health Center for a year to present dual pathology.ResultsThere are significant differences in the frequency of cocaine use among men and women. Eight percent of men use cocaine compared to 0% of women. This monthly cocaine use is more common in women than in men at 45.5% versus 21.8%. Of women, 27.3% use cocaine fortnightly, which is not typical for men (0% of men in the sample). The weekly use of cocaine represents 55.2% among men compared to 27.3% of women.There are no significant differences in the frequency of cannabis use among men and women. Both sexes consume cannabis daily.ConclusionsThe monthly cocaine use is more common in women. In men the most common is the use of cocaine weekly.In both sexes cannabis use is more common daily.Disclosure of interestThe authors have not supplied their declaration of competing interest.


2017 ◽  
Vol 41 (S1) ◽  
pp. S759-S759
Author(s):  
A. Riolo ◽  
F. Babici ◽  
F. Tassi

IntroductionThe polypharmacy is a very controversial subject; it brings together problems of interaction between drugs, side effects, and rationality of co-prescriptions, pharmaco-economic aspects. The long acting is useful to solve adherence to treatment but they are often prescribed in polytherapy.MethodThe aim of this studies is to compare long-acting haloperidol, fluphenazine, risperidone and paliperidone regard to prescribing associations and pharmaco-economy. Also we want to consider for each long-acting which and how many drugs are associated and the implications in terms of pharmaco-economics. We examined all prescriptions (126 patients) over a period of 12 months in a mental health center, identifying which long acting had the best pharmaco-economic profile.ResultsDespite being the less prescribed and not being associated with other psychiatric drugs, paliperidone palmitate shows the best pharmaco-economic profile.ConclusionsThe costs of a drug are in relationship not only with unit price but also with the question of safety in order to oppose the overmedication.Disclosure of interestThe authors have not supplied their declaration of competing interest.


2016 ◽  
Vol 33 (S1) ◽  
pp. S450-S451
Author(s):  
C. Manso Bazús ◽  
J. Valdes Valdazo ◽  
E. Garcia Fernandez ◽  
L.T. Velilla Diez ◽  
J. Min Kim ◽  
...  

IntroductionCurrently, in mental health teams there is overload in the first consultations, therefore, patients cannot be treated properly.ObjectiveThis study tries to reflect the differences between preferential and ordinary consultations, as well as the differences in the delay in the support between them.MethodologyThis is a retrospective observational study where data are collected for 3 months of the first consultations that are taken to a mental health center.ResultsThe study reflects that preferential or normal (ordinary) derivation has no influence when it comes to the patient going or not going to the consultation.On the other hand, there are very significant differences statistically in the waiting time between patients with normal and preferential priority.ConclusionsAccording to the results observed would be advisable to use appropriate criteria to decide the priority of a patient's cares.Disclosure of interestThe authors have not supplied their declaration of competing interest.


2011 ◽  
Vol 47 (6) ◽  
pp. 654-659 ◽  
Author(s):  
Dawn I. Velligan ◽  
Elisa Medellin ◽  
Meredith Draper ◽  
Natalie Maples ◽  
Albana Dassori ◽  
...  

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