Mutual influence between mood disorders and personality disorders

IntroductionSeveral studies have explored the vulnerability to mood disorders that constitute some personality traits.AimsTo study the potential relationship between mood disorders and personality disorders.ObjectiveWe hypothesized that personality disorders can be related to severe mood disorders.MethodsThis was a retrospective study including the period from January 2000 till September 2015 and related to patients in whom the diagnosis of mood disorder and personality one were retained according to the criteria of the DSM-IV TR while the sociodemographic and clinical were collected by a pre-established railing.ResultsWe included 28 patients (15 ♂, 13 ♀). The average age was 38 years. Eighteen (64.3%) patients (7 ♂, 11 ♀) are unemployed. Fifteen patients (10 ♂, 5 ♀) were schooled until secondary level. Seventeen patients (60.7%) were married. The bipolar I disorder (BD I) was most frequently founded (50%), followed by the major depressive disorder in 25% (n = 7) then by the bipolar II disorder in 21.4% (n = 6). A case of dysthymia was also noted. Half of the personality disorders were the borderline type, followed by the histrionic type in 28.6% (n = 8) then by the antisocial in 17.9% (n = 5) and finally one patient presented a paranoiac personality. The antisocial personality was significantly associated with the BD I (P = 0.011) and half of the patients with a pathological personality, presented a depressive symptomatology.ConclusionThe personality disruption is a factor of severity of the thymic disorders. Consequences on the management of patients and their response to treatments remain available.Disclosure of interestThe authors have not supplied their declaration of competing interest.

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Circadian Rhythm Characteristics in Mood Disorders: Comparison among Bipolar I Disorder, Bipolar II Disorder and Recurrent Major Depressive Disorder

Clinical Psychopharmacology and Neuroscience ◽

10.9758/cpn.2012.10.2.110 ◽

2012 ◽

Vol 10 (2) ◽

pp. 110-116 ◽

Cited By ~ 33

Author(s):

Jae Kyung Chung ◽

Kyu Young Lee ◽

Se Hyun Kim ◽

Eui-Joong Kim ◽

Seong Hoon Jeong ◽

...

Keyword(s):

Major Depressive Disorder ◽

Circadian Rhythm ◽

Depressive Disorder ◽

Mood Disorders ◽

Major Depressive ◽

Bipolar Ii Disorder ◽

Bipolar I Disorder ◽

Bipolar Ii ◽

Recurrent Major Depressive Disorder

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Mood Disorders

10.1093/med/9780190265557.003.0018 ◽

2017 ◽

Author(s):

Harvinder Singh ◽

Brian Frankel

Keyword(s):

Bipolar Disorder ◽

Major Depressive Disorder ◽

Depressive Disorder ◽

Mood Disorders ◽

Major Depressive ◽

Bipolar Ii Disorder ◽

Bipolar I Disorder ◽

Bipolar Ii ◽

Cyclothymic Disorder ◽

Persistent Depressive Disorder

In this chapter the topics that are reviewed include major depressive disorder, persistent depressive disorder (dysthymia), unspecified depressive disorder, bipolar I disorder, bipolar II disorder, cyclothymic disorder and unspecified bipolar disorder

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Association between the 5-HTTLPR genotype and childhood impulsivity in subjects with bipolar II disorder

European Psychiatry ◽

10.1016/j.eurpsy.2016.01.1168 ◽

2016 ◽

Vol 33 (S1) ◽

pp. S334-S334

Author(s):

E.J. Kim

Keyword(s):

Mood Disorders ◽

Rating Scale ◽

Small Sample Size ◽

Small Sample ◽

Bipolar Ii Disorder ◽

Childhood Adhd ◽

Mood Instability ◽

Bipolar Ii ◽

Competing Interest ◽

Normal Controls

ObjectiveIt has been suggested that the features of childhood ADHD are significantly associated with adult mood disorders. Some genetic factors may be common to both ADHD and mood disorders underlie the association between these two phenotypes. The present study aimed to determine whether a genetic role may be played by the serotonin transporter-linked polymorphic region (5-HTTLPR) in the childhood ADHD features of adult patients with mood disorders.MethodsThe present study included 232 patients with MDD, 154 patients with BPD, and 1288 normal controls. Childhood ADHD features were assessed with the Korean version of the Wender Utah Rating Scale. The total score and the scores of three factors (impulsivity, inattention, mood instability) from the WURS-K were analyzed to determine whether they were associated with the 5-HTTLPR genotype.ResultsIn the BPD II group, the 5-HTTLPR genotype was significantly associated with the total score (P = 0.029) and the impulsivity factor (P = 0.004) on the WURS-K. However, the inattention and mood instability factors were not associated with the 5-HTTLPR genotype, and the MDD and normal control groups did not exhibit any significant associations between the WURS-K scores and the 5-HTTLPR genotype.ConclusionThe present findings suggest that the 5-HTTLPR genotype may play a role in the impulsivity component of childhood ADHD in patients with BPD II. Because of a small sample size and a single candidate gene, further studies investigating other candidate genes using a larger sample are warranted to more conclusively determine any common genetic links.Disclosure of interestThe author has not supplied his declaration of competing interest.

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Footnotes to Kraepelin: Changes in the classification of mood disorders with DSM-5

BJPsych Open ◽

10.1192/bjpo.bp.117.004739 ◽

2017 ◽

Vol 3 (3) ◽

pp. e1-e3 ◽

Cited By ~ 1

Author(s):

Nicola J. Kalk ◽

Allan H. Young

Keyword(s):

Major Depressive Disorder ◽

Depressive Disorder ◽

Mood Disorders ◽

Bipolar Affective Disorder ◽

Major Depressive ◽

Bipolar Ii Disorder ◽

Diagnostic And Statistical Manual ◽

Dsm 5 ◽

Bipolar Ii

SummaryReliable diagnosis of mood disorders continues to pose a challenge. This is surprising because they have been recognised clinically since classical times. Mood disorders are also common: major depressive disorder affects nearly 300 million people worldwide and bipolar affective disorder nearly 60 million and they are a major cause of disability. Nonetheless, the reliability trials of the updated Diagnostic and Statistical Manual, Fifth Edition (DSM-5) found that the reliability of the diagnosis of major depressive disorder was in the 'questionable' range. Although the reliability of the diagnosis of bipolar I disorder in the same trials was 'good', the sample size of the individuals recruited to validate bipolar II disorder was insufficient to confirm reliability. As the epidemiological prevalences of bipolar I and bipolar II disorders are the same, this alone implies problems in its recognition. Here, we critically evaluate the most recent iteration of DSM mood disorder diagnoses in a historical light and set out the implications for clinical practice and research.

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Polarised views about bipolar disorder(s): A critique of the 2020 College guidelines for mood disorders

Australian & New Zealand Journal of Psychiatry ◽

10.1177/00048674211020095 ◽

2021 ◽

pp. 000486742110200

Author(s):

Gordon Parker

Keyword(s):

Bipolar Disorder ◽

Mood Disorders ◽

International Classification Of Diseases ◽

Bipolar Ii Disorder ◽

Statistical Manual ◽

Diagnostic And Statistical Manual ◽

Bipolar Ii ◽

Classification Of Diseases ◽

Formal Status

The 2020 College guidelines for mood disorders banish bipolar II disorder – despite its formal status in Diagnostic and Statistical Manual of Mental Disorders and International Classification of Diseases manuals for more than two decades – and argue that there is no need to partition bipolar disorder into separate sub-types. Their single-entity model is seemingly based on opinion rather than any support from referenced scientific studies. The author challenges the Committee’s model of there being only one bipolar disorder and argues that it presents several clinical management risks, particularly of ‘over-treatment’.

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