The role of personality and trait affectivity on delusional ideation

2017 ◽  
Vol 41 (S1) ◽  
pp. S747-S748
Author(s):  
M. Tonna ◽  
F. Paglia ◽  
R. Ottoni ◽  
P. Ossola ◽  
C. De Panfilis ◽  
...  
Keyword(s):  
Structured Interview ◽  
Dimensional Structure ◽  
Italian Version ◽  
Pathological Narcissism ◽  
Delusional Ideation ◽  
Competing Interest ◽  
Image Position ◽  
Personality Features ◽  
Trait Affectivity

ObjectiveThe relationship between personality and delusional ideation in still debated. The present study was aimed to evaluate the role of personality features and trait affectivity on the severity of delusional beliefs, through the lens of a dimensional approach. In fact, robust evidence suggests that delusional experience presents a dimensional structure rather than an all-or-nothing fashion with a severity gradient of delusional beliefs from general population to full-blown delusional disorder (DD).MethodForty-nine inpatients affected by DD and 42 non-delusional outpatients were administered the structured interview for DSM-IV Personality Disorders, the Pathological Narcissism Inventory–Italian Version, the Positive and Negative Affect Schedule and the Peters et al. 33–Italian version.ResultsSeverity of delusional ideation was positively related to “hiding the self” (HS) domain of narcissistic vulnerability and to paranoid traits and negatively related to “positive affect” (PA). Paranoid traits and HS significantly interacted in influencing delusional dimension severity (Fig. 1). Low PA represents a trait affectivity of sadness and lethargy whereas HS is closely related to the experience of shame. We speculate that lower levels of PA and higher levels of HS may grasp the “asthenic” pole of Kretschmer's “sensitive character”.ConclusionThe study findings suggest that the severity of delusional ideation depends, at least in part, on a complex interplay between specific affective and paranoid dispositions within personality. Delusion may constitute the superficial shell, which develops from and cover inner affective vulnerabilities of personality.Fig. 1Disclosure of interestThe authors have not supplied their declaration of competing interest.

Efficacy of memantine in schizophrenic patients: A systematic review

2017 ◽  
Vol 41 (S1) ◽  
pp. s824-s824
Author(s):  
C. Montemitro ◽  
M.C. Spano ◽  
M. Lorusso ◽  
G. Baroni ◽  
G. Di Iorio ◽  
...  
Keyword(s):  
Negative Symptoms ◽  
Positive Symptoms ◽  
Aspartate Receptor ◽  
Sigma 1 ◽  
Schizophrenic Patients ◽  
Promising Treatment ◽  
High Concentrations ◽  
Competing Interest ◽  
Image Position

IntroductionSeveral evidences support the hypothesis that glutamatergic dysfunction may be implicated in the pathogenesis of schizophrenia and in the last few year great interest has been focused on the role of the N-methyl-D-aspartate receptor (NMDAR). Memantine is a noncompetitive NMDARs antagonist, binds the same site of NMDARs of Mg2+, endogenous blocker of NMDARs, with moderate affinity, rapid unblocking kinetics and strong functional voltage-dependency. Memantine does not affect the physiological activation of NMDARs whereas it blocks the sustained activation under pathological conditions. Preclinical studies have demonstrated that memantine at high concentrations targets many receptors, including serotonin, nicotinic acetylcholine, sigma-1 and serotonin and dopamine receptors.ObjectivesIncreasing interest in memantine add-on therapy in schizophrenic patients with negative and cognitive symptoms may suggest that memantine could be a new promising treatment in schizophrenia.AimsThe aim of this update was to evaluate clinical data about the memantine effectiveness in schizophrenic patients.MethodsWe searched on PubMed to identify original studies about the use of memantine in treatment of schizophrenic patients. The search conducted on June 16th, 2016 yielded 135 records. Neuf papers met our inclusion criteria.ResultsNegative symptoms improved in the large majority of patients treated, however there is not a clear evidence on cognitive and positive symptoms (Table 1)ConclusionsMemantine therapy in schizophrenic patients has given unclear results. It seems that memantine improves mainly negative symptoms, while cognitive and positive symptoms did not improve significantly. Further trials with a more numerous sample are required obtain an objective result.Table 1Observation during Memantime administration.↓: reduction in severity of symptoms; -: no relevant modifications; +: onset of new symptomsDisclosure of interestThe authors have not supplied their declaration of competing interest.

The predictive role of insight for the evolution of the disease in Romanian patients diagnosed with schizophrenia

2017 ◽  
Vol 41 (S1) ◽  
pp. s809-s809
Author(s):  
C.A. Crisan ◽  
S. Pintea ◽  
I. Miclutia ◽  
R. Macrea
Keyword(s):  
Predictive Factors ◽  
Psychosocial Functioning ◽  
Urban Areas ◽  
Structured Interview ◽  
Psychotic Symptoms ◽  
Psychiatric Clinic ◽  
Predictive Role ◽  
Competing Interest ◽  
Demographical Data

IntroductionSchizophrenia is a serious disorder that influences all life aspects of the patients. The most important goals in schizophrenia are remission, recovery, improving psychosocial functioning and quality of life, which can be influenced by different factors, especially insight.ObjectivesTo evaluate the awareness of illness in Romanian patients diagnosed with schizophrenia and to determine the predictive role of insight.AimsThis study wants to highlight the importance of the evaluation of insight in psychotic patients, taking into account that awareness leads to compliance with treatment, decreased rate of relapses and rehospitalization and a better prognosis.Material and methodsOverall, 80 patients (44 males and 36 females) recruited from first and second psychiatric clinic Cluj-Napoca, diagnosed according to ICD-10 and DSM-V criteria with schizophrenia and acute psychotic disorder participated in this study. A semi-structured interview collected demographical data. Psychotic symptoms were evaluated using PANSS, severity of the disease using CGI and insight using SUMD.ResultsOur results showed that the most important predictive factors for the evolution were: level of insight (r = −0.41 P < 0.01), presence of family history (r = 0.24 P < 0.05) and belonging to urban areas (r = 0.23 P < 0.05). The level of insight explained 16% of variance of improving psychotic symptoms during hospitalization.ConclusionsThe awareness of illness is one of the predictive factors for long-term schizophrenia and the best predictive model of disease progression is composed of variables SUMD total and PANSS total on admission.Disclosure of interestThe authors have not supplied their declaration of competing interest.

Validation of the Italian Version of the “abnormal Bodily Phenomena Questionnaire” in a Sample of Patients with Schizophrenia: Preliminary Data

2017 ◽  
Vol 41 (S1) ◽  
pp. S80-S80
Author(s):  
M. Chieffi ◽  
D. Palumbo ◽  
S. Patriarca ◽  
G. Plescia ◽  
V. Montefusco ◽  
...  
Keyword(s):  
Preliminary Data ◽  
Convergent Validity ◽  
Structured Interview ◽  
Clinical Severity ◽  
Experimental Sample ◽  
Italian Version ◽  
Symptom Scale ◽  
Syndrome Scale ◽  
Competing Interest ◽  
Severity Of The Disease

IntroductionThe abnormal bodily phenomena questionnaire (ABPq) originates from the analysis of clinical files of more than 350 patients with schizophrenia. It consists in a semi-structured interview created to evaluate the subjective anomalies in feelings, sensations, perceptions and cognition in the domain of the lived body.ObjectivesThe present study is aimed at providing preliminary data for the validation of the Italian version of the ABPq.MethodsThe ABPq was translated and adapted into Italian. ABPq scores were correlated to those obtained by the schizophrenia proneness instrument, Adult version–body perception disturbances (SPI-A E, body) that evaluates the same kind of phenomena, in order to examine its convergent validity. Moreover, ABPq was correlated to psychopathological domains assessed by the Positive and Negative Syndrome Scale (PANSS) and by the Brief Negative Symptom Scale (BNSS).ResultsThe experimental sample included 40 clinically stable patients. Our findings showed a strong correlation between ABPq and SPI-A E, body. An association of ABPq total score with the positive and disorganized dimensions was also observed.ConclusionsOur preliminary data suggest that the Italian version of ABPq has a good convergent validity. The presence of abnormal bodily phenomena resulted to be associated to a greater severity of the disease and therefore it could be hypothesized that they represent an indicator of clinical severity.Disclosure of interestThe authors have not supplied their declaration of competing interest.

The role of differential phase contrast in electron microscopy

1978 ◽  
Vol 36 (1) ◽  
pp. 176-177
Author(s):  
E.M. Waddell ◽  
J.N. Chapman ◽  
R.P. Ferrier
Keyword(s):  
Phase Contrast ◽  
Practical Method ◽  
Position Vector ◽  
Differential Phase ◽  
Pure Phase ◽  
Differential Phase Contrast ◽  
The Difference ◽  
Image Position ◽  
First Moment

Dekkers and de Lang (1977) have discussed a practical method of realising differential phase contrast in a STEM. The method involves taking the difference signal from two semi-circular detectors placed symmetrically about the optic axis and subtending the same angle (2α) at the specimen as that of the cone of illumination. Such a system, or an obvious generalisation of it, namely a quadrant detector, has the characteristic of responding to the gradient of the phase of the specimen transmittance. In this paper we shall compare the performance of this type of system with that of a first moment detector (Waddell et al.1977).For a first moment detector the response function R(k) is of the form R(k) = ck where c is a constant, k is a position vector in the detector plane and the vector nature of R(k)indicates that two signals are produced. This type of system would produce an image signal given bywhere the specimen transmittance is given by a (r) exp (iϕ (r), r is a position vector in object space, ro the position of the probe, ⊛ represents a convolution integral and it has been assumed that we have a coherent probe, with a complex disturbance of the form b(r-ro) exp (iζ (r-ro)). Thus the image signal for a pure phase object imaged in a STEM using a first moment detector is b2 ⊛ ▽ø. Note that this puts no restrictions on the magnitude of the variation of the phase function, but does assume an infinite detector.

The Role of Interpersonal Communication in Students’ Self-control to Avoid Substance Abuse

2020 ◽  
Vol 5 (2) ◽  
pp. 84-94
Author(s):  
Ade Tuti Turistiati ◽  
Baby Poernomo
Keyword(s):  
High School Students ◽  
Drug Abuse ◽  
Interpersonal Communication ◽  
Junior High School ◽  
Phenomenological Approach ◽  
Structured Interview ◽  
Self Control ◽  
School Students ◽  
Qualitative Research Design

This study aims at answering the questions what causes many junior high school students fall into drug abuse, and what kind of treatment  must be done so that students have self-control and are not subject to drug abuse. This study employed a phenomenological approach of a qualitative research design.  In this study a semi-structured interview is used to understand how participants experienced the phenomenon. The research revealed that the interpersonal communication has a major role in students' self-control so as not to fall into drug abuse. This study contributes significantly to educational field particularly teachers in secondary schools so that it can be used as a reference to provide counseling to parents about the importance of interpersonal communication to build students’ self-control to prevent teens from falling into drug abuse.

Cultural knowledge and treatment of childhood illness

2016 ◽  
Vol 5 (09) ◽  
pp. 4802
Author(s):  
Izabel Cristina Santiago Lemos ◽  
Giovana Mendes De Lacerda ◽  
Maysa de Oliveira Barbosa ◽  
Gyllyandeson de Araújo Delmondes ◽  
Patrícia Rosane Leite de Figueiredo ◽  
...  
Keyword(s):  
Traditional Knowledge ◽  
Health Professionals ◽  
Respiratory Infections ◽  
Structured Interview ◽  
Cultural Knowledge ◽  
Childhood Illness ◽  
Care Practice ◽  
Childhood Illnesses ◽  
Popular Knowledge

Traditional knowledge emerges as a relevant figure in care used by mothers and caregivers for the management of acute respiratory infections, diarrhea and anemia. To understand the meaning given to the use of traditional knowledge by mothers or caregivers for the treatment of these illnesses, their reflexes to conventional treatment, as well as discuss the role of health professionals with regard to the use of plants and animals by mothers or responsible for the management the respiratory infections; diarrhea and anemia. The research was conducted in Santo Antônio community (Barbalha - CE). Techniques as “rapport” and “Snowball” were used for data collection, and a closed questionnaire and semi-structured interview were applied. For data analysis, the Collective Subject Discourse (CSD) was used. The sample included 54 informants. There were 19 key ideas identified, which revealed an appreciation of the use of natural resources to treat the respiratory infections; diarrhea and anemia, an association between conventional and traditional medicine in the management these common childhood illnesses and the need for health professionals value the popular knowledge in assistance provided. Health professionals are encouraged to include behaviors in their care practice that allow greater contact with local cultures, being able to measure what resources are used and how they can interfere on the prescribed therapy.

The role of personality traits in initiating and maintaining addictive behavior

2016 ◽  
Vol 33 (S1) ◽  
pp. S307-S307
Author(s):  
M. Manea ◽  
B. Savu
Keyword(s):  
Substance Abuse ◽  
Anxiety Disorders ◽  
Personality Traits ◽  
Trait Anxiety ◽  
Psychiatric Clinic ◽  
Strongly Correlated ◽  
Addictive Disorder ◽  
Substance Disorders ◽  
Competing Interest

IntroductionIt is well known that certain personality traits are more linked to drug abuse than others. Psychiatrists are more likely to emphasize the importance of impulsivity in the connection with substance disorders but in the following study we found an important percentage of patients that have a substance abuse were linked to anxiety through impulsiveness as a personality trait.ObjectivesMost youths admitted for a substance abuse are highly impulsive. Our quest was to differentiate what component of impulsivity was more frequently linked to a substance use disorder.MethodsIn the study were included 50 patients admitted in the 3rd Psychiatric Clinic, Substance Dependences Department, Cluj-Napoca. For the identification of the drug abused we used the multitest screening kit in correlation with the results from the Forensic Medicine Institute of Cluj-Napoca. Each patient completed the Barratt Impulsivity Scale and the Swedish Universities Scales of Personality.ResultsHigh scores on BIS-11 strongly correlated with attentional impulsiveness (Pearson's r correlation = .838) which means high inattention and cognitive instability this being linked with anxiety disorders. Cognitive Instability was correlated with Psychic Trait Anxiety (r = 0.29) and Motor Impulsiveness with Somatic Trait Anxiety (r = 0.3). Normal 0 false false false EN-US X-NONE X-NONE.ConclusionsThe underrecognized anxiety disorders in young adults whom are admitted for an addictive disorder prefrontal cortex is known to be the source of both impulsivity and could be linked to anxiety as well (valence asymmetry hypothesis). Normal 0 false false false EN-US X-NONE X-NONE.Disclosure of interestThe authors have not supplied their declaration of competing interest.

The role of the clinical pharmacist in guiding adjuvant hormonal therapy in patients with breast cancer

2021 ◽  
pp. 107815522110293
Author(s):  
Amanda V Pirolli ◽  
Tatiana Brusamarello ◽  
Stella S Everton ◽  
Vânia M S Andrzejevski
Keyword(s):  
Breast Cancer ◽  
Hormone Therapy ◽  
Hormonal Therapy ◽  
Clinical Pharmacist ◽  
Tertiary Care ◽  
Structured Interview ◽  
Care Hospital ◽  
Adjuvant Hormonal Therapy ◽  
Breast Cancers

Breast cancer is the most prevalent type of cancer among women, affecting about 2.1 million worldwide and is responsible for the highest number of cancer-related deaths among women. Approximately 80% of breast cancers express on the surface of hormone receptor cells, such as progesterone and estrogen. In these cases, Adjuvant Hormonal Therapy (AHT) is indicated for a period of five to ten years and consists of taking a daily oral pill. The two most used drugs in AHT are tamoxifen and Aromatase Inhibitors. One of the issues most faced by individuals who are subjected to long periods of treatment is the lack of medication adherence and, consequently, therapeutic inefficiency. It is believed that the monitoring by the pharmacist can contribute to the reduction of errors inherent to the medication, making the treatment more effective and improving the patient's quality of life. The present study aimed to know the perception of patients who live with breast cancer and who do AHT in relation to the educational performance of the clinical pharmacist. This is a qualitative, descriptive and exploratory study, carried out from March to October 2020, with 15 women undergoing treatment at the oncology unit of a tertiary-care hospital in south of Brazil. The data were obtained through a semi-structured interview using an instrument composed of two parts, one referring to the characterization of the participants and the other with the guiding question of the research: "How do you perceive the role of the pharmacist in relation to the guidelines for the use of adjuvant hormonal therapy?". The method of theoretical saturation was used to perform the sample closure and the thematic analysis was used to analyze the data. The participants were between 32 and 74 years old, seven were on tamoxifen therapy and eight on anastrozole, ten were on the first year of treatment, two on the second and three on the third year. The themes that emerged were: pharmacist-patient interaction as a safety factor in hormone therapy; role of the pharmacist in the development of strategies for self-management of the patients during hormone therapy; and, challenges for the pharmacist in relation to hormone therapy through continued guidance. It was evident that the pharmacist's educational action encouraged the participants to carry out the treatment in a more confident and assertive manner according to their particularities and beliefs.

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