scholarly journals Effects of acute alcohol consumption and vitamin E co-treatment on oxidative stress parameters in rats tongue

2009 ◽  
Vol 47 (6) ◽  
pp. 1058-1063 ◽  
Author(s):  
V.C. Carrard ◽  
A.S. Pires ◽  
M. Mendez ◽  
F. Mattos ◽  
J.C.F. Moreira ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Vitamin E ◽  
Alcohol Consumption ◽  
Oxidative Stress Parameters ◽  
Stress Parameters

scholarly journals Changes in Oxidative Stress Parameters as Response to Supplementation With Vitamin E and Omega-3 Fatty Acids in Male Workers Exposed to High Level Noise

2021 ◽  
Author(s):  
Hamzeh Mohammadi ◽  
Farideh Golbabaei ◽  
Somayeh Farhang Dehghan ◽  
Nariman Moradi ◽  
Maryam Chamari ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Fatty Acids ◽  
Vitamin E ◽  
Assay Method ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Decremental Effect ◽  
Oxidative Stress Parameters ◽  
Incremental Effect ◽  
Stress Parameters

Abstract Background: The present study aimed to assess the effects of the supplementation consumption of vitamin E and Omega 3 fatty acid on the oxidative stress parameters among workers exposed to high levels of noise in an automobile parts manufacturing plant. Moreover, the effects of the exposure to noise on SOD, total oxidative stress (TAC) and MDA will be investigated. Methods: The participants were deployed into 4 groups (vitamin E (100 mg), Omega 3 fatty acids (180 mg EPA and 120 mg DHA), vitamin E+ Omega 3 and Placebo), as per the double-blind block randomization method. The oxidative stress parameters of the participants were analyzed before and after three month consumption of supplements via enzyme-linked immunosorbent assay method. The level of workers' exposure to noise, was measured according to ISO 9612. Results: Before intervention, mean MDA, SOD and TAC were 27.52 (7.46) nmol/ml, 58.84 (10.44) U/ml and 2.57 (0.67) mM respectively. After intervention, mean MDA, SOD and TAC were 24.57 (7.58) nmol/ml, 63.46 (11.02) U/ml and 2.70 (0.84) mM respectively. The use of supplement Omega 3 fatty acids had a significant decremental effect on MDA levels. The use of vitamin E alongside Omega 3 fatty acids had a significant incremental effect on SOD activity.Conclusion: Noise exposure had a decremental effect on TAC and SOD as well as an incremental effect on MDA, but this was only statistically significant for TAC. It appears that the simultaneous use of vitamin E and Omega 3 fatty acids for three months had a positive effect on the anti-oxidant performance of workers exposed to noise.

scholarly journals Is the Clinical Course of Non-Arteritic Ischemic Optic Neuropathy Associated with Oxidative Damage and the Dynamics of the Antioxidant Response?

2022 ◽  
Author(s):  
kaya N engin ◽  
Duygu Harmancı Karagülle ◽  
Ceren Durmaz Engin ◽  
Melis Kant ◽  
Aylin Yaman ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Vitamin E ◽  
Oxidative Damage ◽  
Patient Group ◽  
Optic Neuropathy ◽  
Clinical Course ◽  
Antioxidant Response ◽  
Ischemic Optic Neuropathy ◽  
Oxidative Stress Parameters ◽  
Stress Parameters

Abstract Purpose: Oxidative stress is known to be a decisive factor in the wide etiopathogenesis of optic neuropathy. This study aimed to comprehensively evaluate the interaction of optic neuropathy’s clinical course with systemic oxidative damage and antioxidant response dynamics in a large series.Methods: This case-controlled clinical study included 33 non-arteritic anterior ischemic optic neuropathy patients and 32 healthy individuals. Extensive systemic oxidation profiles were statistically compared between the two groups, and correlations between the clinical and biochemical data in the patient group were analyzed.Results: Vitamin E and MDA levels were significantly higher in the patient group. Significant correlations were observed in the analyses between clinical findings and oxidative stress parameters. Correlations between vitamin E and intraocular pressure, between B12 and cup-to-disc ratio, between antioxidant glutathione and SOD enzyme systems, and between uric acid and age were found to be very significant. As significant correlations were found in either clinical and biochemical data or in oxidative stress parameters, correlations between vitamin E and cholesterol, MDA was found to be very significant. Conclusions: This study not only supplies significant information regarding oxidative damage and antioxidant response in NAION, but also points out the specific interactions of neuromodulators, like vitamin E, in intracellular signaling pathways and regulation mechanisms. A better reading of these connections may help improve diagnosis, follow-ups and treatment criteria and strategies.

Evaluation of aspect of some oxidative stress parameters using vitamin E, proanthocyanidin and N-acetylcysteine against exposure to cyfluthrin in mice

2007 ◽  
Vol 88 (1) ◽  
pp. 43-49 ◽  
Author(s):  
Gokhan Eraslan ◽  
Sahan Saygi ◽  
Dinc Essiz ◽  
Abdurrahman Aksoy ◽  
Husamettin Gul ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Vitamin E ◽  
Oxidative Stress Parameters ◽  
Stress Parameters

Effect of omega-3 fatty acid plus vitamin E Co-Supplementation on oxidative stress parameters: A systematic review and meta-analysis

2020 ◽  
Vol 39 (4) ◽  
pp. 1019-1025 ◽  
Author(s):  
Mahdi Sepidarkish ◽  
Maryam Akbari-Fakhrabadi ◽  
Elnaz Daneshzad ◽  
Mahsa Yavari ◽  
Mahroo Rezaeinejad ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Systematic Review ◽  
Fatty Acid ◽  
Vitamin E ◽  
Meta Analysis ◽  
Omega 3 ◽  
Omega 3 Fatty Acid ◽  
Oxidative Stress Parameters ◽  
Stress Parameters

scholarly journals Sublethal Toxicity of Thiamethoxam Insecticide in Albino Mice: Biochemical, Oxidative Damage and Histopathological Evaluations

2020 ◽  
Vol 4 (1) ◽  
pp. 017-028
Author(s):  
Gamal Elsayed Abouelghar ◽  
Rania Ibrahim Yassien ◽  
Zeinab Abd-Elghany El-Bermawy ◽  
Hager Ali Ammar ◽  
Yassmin Abd-Elaziz Shalaby
Keyword(s):  
Oxidative Stress ◽  
Vitamin E ◽  
Toxicity Study ◽  
Repeated Dose ◽  
Oral Toxicity ◽  
Oxidative Stress Parameters ◽  
Ameliorative Effect ◽  
Sublethal Doses ◽  
Albino Mice ◽  
Stress Parameters

The Neonicotinoid insecticides are presently used in great amounts, but this can be a problem when the possible risks of occupational and environmental contamination are considered. The objective of this study was to investigate the potential adverse effects of sublethal doses of Thiamethoxam insecticide on serum biochemical, oxidative stress and histological alterations in male albino mice via 28-day repeated-dose oral toxicity study. The possible ameliorative effect of selenium plus vitamin E against the harmful effects of Thiamethoxam was also investigated. Mice in Thiamethoxam-treated groups received three sublethal doses (6, 12, and 30 mg/kg b.w./day). Animals in another group were orally co-administered selenium + vitamin E with the higher dose of insecticide. The results showed that Thiamethoxam significantly (p < 0.05) increased cholesterol levels and liver enzyme activities, in dose-dependent manner, compared to those of the control group. Levels of creatinine were not significantly changed, whereas uric acid increased at high doses. The oxidative stress parameters were significantly increased in association with decrease in total antioxidants level. The histological analysis revealed that the higher dose induced various alterations in tissues of vital organs, i.e. liver, kidney, lung and testes. Interestingly, the ameliorative effect of selenium + vitamin E in restoring the oxidative stress parameters was reflected by reducing severity of histopathological lesions. In conclusion, it appears that the sublethal dose < 6.0 mg/kg b.w./day, in repeated dose 28-day oral toxicity study, in male albino mice may be considered as No-Observed-Adverse-Effect-Level (NOAEL) of Thiamethoxam. Additionally, the antioxidant selenium, in mixture with vitamin E, showed an ameliorative effect against Thiamethoxam-induced toxicity.

scholarly journals Influence of sevoflurane or propofol anaesthesia on oxidative stress parameters in dogs with early-stage myxomatous mitral valve degeneration. A preliminary study

2018 ◽  
Vol 68 (1) ◽  
pp. 32-42 ◽  
Author(s):  
Tomsič Katerina ◽  
Nemec Svete Alenka ◽  
Nemec Ana ◽  
Domanjko Petrič Aleksandra ◽  
Vovk Tomaž ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Vitamin E ◽  
Mitral Valve ◽  
Glutathione Peroxidase ◽  
Early Stage ◽  
Glutathione Peroxidase Activity ◽  
Oxidative Stress Parameters ◽  
Preliminary Study ◽  
Stress Parameters

Abstract The aim of this study was to investigate the effects of total intravenous anaesthesia with propofol and anaesthesia induced with propofol and maintained with sevoflurane on oxidative stress parameters in dogs with early-stage myxomatous mitral valve degeneration (MMVD). Sixteen client-owned dogs with early stage MMVD that required periodontal treatment were included in the study. After induction with propofol, anaesthesia was maintained with propofol (group P) or sevoflurane (group PS). Blood samples for determination of vitamin E, superoxide dismutase, glutathione peroxidase and malondialdehyde were collected before premedication, 5 and 60 minutes and 6 hours after induction to anaesthesia. There were no significant differences between groups in any of the oxidative stress parameters at each sampling time. Compared to basal values, vitamin E concentration decreased significantly during anaesthesia in both groups and glutathione peroxidase activity increased 60 minutes after induction to anaesthesia in PS group. Anaesthesia with propofol or with propofol and sevoflurane did not have any significant impact on oxidative stress parameters in dogs with early stage MMVD. In terms of oxidative stress, both protocols may be equally safely used in dogs with early stage MMVD.

Sign in / Sign up

Export Citation Format

Share Document