AbstractFor nearly four decades, the expansion of tobacco has been recognized as one of eight technologies significant in the design of a ‘less hazardous’ cigarette. The data previously presented at scientific conferences and/or published in several scientific monographs and journals on the effect of the expansion of tobacco on the composition and biological properties of the mainstream smoke from cigarettes containing it are summarized. In addition, previously unpublished data on the same subjects are presented in considerable detail. Included are 1) the effect of tobacco expansion on the yields of total particulate matter (TPM), nicotine, and several hundred components of cigarette mainstream smoke from control tobacco cigarettes vs. expanded tobacco cigarettes; 2) the changes in mainstream smoke yields of total particulate matter, nicotine, and specific smoke components produced by inclusion of various levels of expanded tobacco in a cigarette blend; and 3) the changes in composition of expanded tobacco. In the latter study, the decrease in levels of numerous significant flavorful components of the tobacco produced by expansion provides the need for inclusion of such compounds in flavor formulations. In study 2), the reductions in per cigarette yields of total particulate matter, nicotine, and several components of concern were determined and confirmed the significance of tobacco expansion as a cigarette design technology to produce what was originally defined as a ‘less hazardous’ cigarette but more recently as a ‘potential reduced exposure product’ (PREP).
Transfer of Added [18-14C]Octatriacontane - Cigarette Smoke Formation Studies