Evaluation of genotoxic effects of semicarbazide on cultured human lymphocytes and rat bone marrow

2010 ◽  
Vol 48 (1) ◽  
pp. 209-214 ◽  
Author(s):  
Dimitris Vlastos ◽  
Hariklia Moshou ◽  
Klimentini Epeoglou
Author(s):  
Georgia Demsia ◽  
Dimitris Vlastos ◽  
Marina Goumenou ◽  
Demetrios P. Matthopoulos

2017 ◽  
Vol 149 (2) ◽  
pp. 127-141 ◽  
Author(s):  
Sabiha M. Ansari ◽  
Quaiser Saquib ◽  
Sabry M. Attia ◽  
Eslam M. Abdel-Salam ◽  
Hend A. Alwathnani ◽  
...  

Author(s):  
Ф.Т. Чшиева ◽  
Т.В. Чшиев ◽  
Р.И. Кокаев

При хроническом применении мелаксена в дозе 10 мг/кг индукции генотоксических эффектов в костном мозге крыс не выявлено. Метафазный анализ после хронического совместного внутрижелудочного введения соли кадмия 0,3 мг/кг (в пересчете на металл) и мелаксена показал протекторные свойства последнего (р<0,01). There was no reveled induction of genotoxic effects in rat bone marrow at the constant use of “melaxen” at a dose of 10 mg/kg. The chronic joint intragastric injection of a cadmium salt of 0.3 mg / kg (in terms of metal) and “melaxen “ showed the protective properties of the remedy (p<0.01) after metaphase analysis.


2013 ◽  
Vol 31 (3) ◽  
pp. 189-191 ◽  
Author(s):  
Harutyunyan Tigran ◽  
◽  
Karapetyan Anna ◽  
Hovhannisyan Galina ◽  
Aroutiounian Rouben

2004 ◽  
Vol 4 ◽  
pp. 48-54 ◽  
Author(s):  
George Demsia ◽  
Dimitris Vlastos ◽  
Demetrios P. Matthopoulos

Aiming to investigate the possibility of electromagnetic fields (EMF) developed by nonionizing radiation to be a noxious agent capable of inducing genotoxicity to humans, in the current study we have investigated the effect of 910-MHz EMF in rat bone marrow. Rats were exposed daily for 2 h over a period of 30 consecutive days. Studying bone marrow smears from EMF-exposed and sham-exposed animals, we observed an almost threefold increase of micronuclei (MN) in polychromatic erythrocytes (PCEs) after EMF exposure. An induction of MN was also observed in polymorphonuclear cells. The induction of MN in female rats was less than that in male rats. The results indicate that 910-MHz EMF could be considered as a noxious agent capable of producing genotoxic effects.


Author(s):  
A. Balasubramanyam ◽  
N. Sailaja ◽  
M. Mahboob ◽  
M.F. Rahman ◽  
S. Misra ◽  
...  

CYTOLOGIA ◽  
1999 ◽  
Vol 64 (3) ◽  
pp. 277-283 ◽  
Author(s):  
H. B. Ila ◽  
M. Topaktas

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