Protective role of propolis in chlorpyrifos-induced changes in the haematological parameters and the oxidative/antioxidative status of Cyprinus carpio carpio

2012 ◽  
Vol 50 (8) ◽  
pp. 2703-2708 ◽  
Author(s):  
M. Enis Yonar ◽  
Serpil Mişe Yonar ◽  
Mevlüt Şener Ural ◽  
Sibel Silici ◽  
Mustafa Düşükcan
2012 ◽  
Vol 36 (3) ◽  
pp. 320-328 ◽  
Author(s):  
Anne Augustine Williams ◽  
Jayaraman Selvaraj ◽  
Chinnapaiyan Srinivasan ◽  
Sampath Sathish ◽  
Parsanathan Rajesh ◽  
...  

2014 ◽  
Vol 66 (3) ◽  
pp. 1271-1279 ◽  
Author(s):  
Jelena Mladenovic ◽  
Milica Paunovic ◽  
Milos Matic ◽  
Veroljub Knezevic ◽  
Branka Ognjanovic ◽  
...  

The effects of subchronic exposure to copper (Cu) on lipid peroxidation, hemato-biochemical parameters, and the possible protective role of flavonoids Quercetin and (-)-Epicatechin were studied. Male Wistar albino rats were treated with Cu (560 mg/L, p.o. as CuCl2?2H2O for 5 weeks) and Quercetin and (-)-Epicatechin (40 mg/kg BW each, i.p., every third day during the last 3 weeks) alone or in combination. Cu increased the concentration of lipid peroxides, decreased the number of erythrocytes, hemoglobin and hematocrit values and increased the activities of aspartate aminotransferase, alanine aminotransferase and lactate dehydrogenase. Coadministration of Quercetin and (-)-Epicatechin with Cu lowered the process of lipid peroxidation and restored examined hemato-biochemical parameters to control values. Our results indicate that Cu induced oxidative damage in erythrocytes, which led to anemia, while Quercetin and (-)-Epicatechin showed a protective effect on the hemato-biochemical processes in the blood of rats.


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