Surgery-induced changes in red blood cell and plasma lipid peroxidation, enzymatic and non-enzymatic antioxidants, and blood hematology of female rats: protective role of methylene blue and vitamin E

2011 ◽  
Vol 155 (1) ◽  
pp. 89-93 ◽  
Author(s):  
Hamit Yildiz ◽  
Ali Said Durmus ◽  
Halil Simsek
Keyword(s):  
Lipid Peroxidation ◽  
Methylene Blue ◽  
Plasma Lipid ◽  
Protective Role ◽  
Female Rats ◽  
Enzymatic Antioxidants ◽  
Blood Cell And Plasma ◽  
Induced Changes ◽  
Plasma Lipid Peroxidation

Plasma lipid peroxidation in sporadic Parkinson's disease. Role of the l-dopa

2006 ◽  
Vol 240 (1-2) ◽  
pp. 31-36 ◽  
Author(s):  
Ahmad Agil ◽  
Raquel Durán ◽  
Francisco Barrero ◽  
Blas Morales ◽  
Mariano Araúzo ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Lipid Peroxidation ◽  
Parkinson's Disease ◽  
Plasma Lipid ◽  
Sporadic Parkinson’S Disease ◽  
Plasma Lipid Peroxidation

scholarly journals Copper-induced changes of lipid peroxidation and hemato-biochemical parameters in rat blood: Protective role of flavonoids

2014 ◽  
Vol 66 (3) ◽  
pp. 1271-1279 ◽  
Author(s):  
Jelena Mladenovic ◽  
Milica Paunovic ◽  
Milos Matic ◽  
Veroljub Knezevic ◽  
Branka Ognjanovic ◽  
...  
Keyword(s):  
Lipid Peroxidation ◽  
Lactate Dehydrogenase ◽  
Biochemical Parameters ◽  
Lipid Peroxides ◽  
Protective Role ◽  
Albino Rats ◽  
Biochemical Processes ◽  
Wistar Albino Rats ◽  
Induced Changes

The effects of subchronic exposure to copper (Cu) on lipid peroxidation, hemato-biochemical parameters, and the possible protective role of flavonoids Quercetin and (-)-Epicatechin were studied. Male Wistar albino rats were treated with Cu (560 mg/L, p.o. as CuCl2?2H2O for 5 weeks) and Quercetin and (-)-Epicatechin (40 mg/kg BW each, i.p., every third day during the last 3 weeks) alone or in combination. Cu increased the concentration of lipid peroxides, decreased the number of erythrocytes, hemoglobin and hematocrit values and increased the activities of aspartate aminotransferase, alanine aminotransferase and lactate dehydrogenase. Coadministration of Quercetin and (-)-Epicatechin with Cu lowered the process of lipid peroxidation and restored examined hemato-biochemical parameters to control values. Our results indicate that Cu induced oxidative damage in erythrocytes, which led to anemia, while Quercetin and (-)-Epicatechin showed a protective effect on the hemato-biochemical processes in the blood of rats.

Propetamphos-induced changes in haematological and biochemical parameters of female rats: Protective role of propolis

2010 ◽  
Vol 48 (7) ◽  
pp. 1806-1810 ◽  
Author(s):  
Ebru Çetin ◽  
Murat Kanbur ◽  
Sibel Silici ◽  
Gökhan Eraslan
Keyword(s):  
Biochemical Parameters ◽  
Protective Role ◽  
Female Rats ◽  
Induced Changes

scholarly journals The protective effects of selenoorganic compounds against peroxynitrite-induced changes in plasma proteins and lipids

2006 ◽  
Vol 11 (1) ◽  
pp. 1-11 ◽  
Author(s):  
Paweł Nowak ◽  
Joanna Saluk-Juszczak ◽  
Beata Olas ◽  
Joanna Kołodziejczyk ◽  
Barbara Wachowicz
Keyword(s):  
Lipid Peroxidation ◽  
Human Plasma ◽  
Plasma Proteins ◽  
Enzyme Inhibitors ◽  
Group Formation ◽  
Plasma Lipid ◽  
Protective Effects ◽  
Induced Changes ◽  
Plasma Lipid Peroxidation

AbstractMany selenoorganic compounds play an important role in biochemical processes and act as antioxidants, enzyme inhibitors or drugs. The effects of a new selenocompound — bis(2-aminophenyl)-diselenide on oxidative/nitrative changes in human plasma proteins induced by peroxynitrite (ONOO−) were studied in vitro and compared with the those of ebselen, a well-known antioxidant. We also studied the role of the tested selenocompounds in peroxynitrite-induced plasma lipid peroxidation. Exposure of the plasma to peroxynitrite (0.1 mM) resulted in an increase in the level of carbonyl groups and nitrotyrosine residues in plasma proteins (estimated using the ELISA method and Western blot analysis). In the presence of different concentrations (0.025–0.1 mM) of the tested selenocompounds, 0.1 mM peroxynitrite caused a distinct decrease in the level of carbonyl group formation and tyrosine nitration in plasma proteins. Moreover, these selenocompounds also inhibited plasma lipid peroxidation induced by ONOO−1 (0.1 mM). The obtained results indicate that in vitro bis(2-aminophenyl)-diselenide and ebselen have very similar protective effects against peroxynitrite-induced oxidative/nitrative damage to human plasma proteins and lipids.

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