In vitro fertilization (IVF) versus gonadotropins followed by IVF as treatment for primary infertility: a cost-based decision analysis

2005 ◽  
Vol 84 (3) ◽  
pp. 600-604 ◽  
Author(s):  
Suleena Kansal-Kalra ◽  
Magdy P. Milad ◽  
William A. Grobman
Keyword(s):  
In Vitro Fertilization ◽  
Decision Analysis ◽  
Vitro Fertilization ◽  
Primary Infertility

scholarly journals Case Report on Primary Infertility with Hypothyroidism and Diabetes Mellitus

2021 ◽  
pp. 263-266
Author(s):  
Thool Bali ◽  
Lokhande Shalini ◽  
A. Lalawmpuii ◽  
Ambule Kalyani ◽  
Shendre Vaishnavi ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
In Vitro Fertilization ◽  
Sperm Count ◽  
Vitro Fertilization ◽  
Primary Infertility ◽  
History Of ◽  
Irregular Menses ◽  
One Year ◽  
Loss Of Appetite

Introduction: Infertility is the inability, by natural means, of an animal to reproduce. Typically, adult species are not in their normal state of health. A woman who is unable to conceive well will define infertility as unable to bear a full-term pregnancy. Because of any ejaculating disease, and any declining sperm count, men are directly liable for 30-40% infertility. The WHO estimates the overall prevalence of primary infertility in India at 3.9% and 16.8%. Fertility estimates differ widely between India and 3.7% in Utter Pradesh and Maharashtra. Case Presentation: On 9/12/2020, a 38-year-old female came for In Vitro Fertilization with a known case of primary infertility in AVBR Hospital, Wardha. Her complaint was inability to conceive for 4 years, irregular menses, headache, sleep disturbance, loss of appetite. She was admitted for in-vitro fertilization therapy for the 2nd cycle. She had a history of hypothyroidism for 8 years for which she has been taking Thyrox 50mg OD tablet and has Diabetes Mellitus for one year since she is taking Metformin 500mg BD tablet. Instead, she has no concerns about asthma, tuberculosis, epilepsy, etc. On 9/12/2020, she underwent an embryo transfer. Diagnostic Evaluation: The diagnostic hysteroscopy was conducted at the private hospital in Amravati 2 years ago. She has been diagnosed with nullipara for 4 years as a primary infertility. She has already undergone 2 cycles of Intra Uterine Insemination (IUI) and 1 cycle of in vitro fertilization. Hysterosalpingography: Both fallopian tubes are normal & patent uterus is normal. Conclusion: There is multifactorial infertility. In both men and women, anatomy, physiology, the environment, hormones and genetics all play a role in causing infertility. Therefore, in the coming years, it is a very important problem and research in this zone is very essential.

scholarly journals Structural and functional features of endometrium in patients undergoing in - vitro fertilization

2019 ◽  
Vol 10 (1) ◽  
pp. 29-34
Author(s):  
Y. A. Kovalenko ◽  
L. M. Chuprinenko
Keyword(s):  
Menstrual Cycle ◽  
In Vitro Fertilization ◽  
Pregnancy Loss ◽  
Recurrent Pregnancy Loss ◽  
Immunohistochemical Method ◽  
Secondary Infertility ◽  
Vitro Fertilization ◽  
Primary Infertility ◽  
Functional Features

A complex of diagnostic and therapeutic measures had been established in order to overcome many different causes of female infertility and restore women’s reproductive health.The aim of research is to determine value of immunohistochemical method in determination of disregenerative condition of endometrium in patients undergoing in - vitro fertilization (IVF) program. Materials and methods. The research included 62 patients treated according to IVF program in Clinic of FSBI HPE KSMU NOH Russia, Krasnodar city, in 2017 year. Data of history of disease, laboratory diagnostics, hormonal monitoring at 2-3 day of menstrual cycle and dynamic ultrasound investigation were processed. To evaluate urogenital microbiocenosis real - time PCR was used with “Femoflor-16” kit. Pipelle - biopsy of endometrium was taken at 22-24 day of menstrual cycle. Results. After certain investigation patients were divided into three groups. First group consisted of 18 (29.03%) women with primary infertility, second group - 17 (27.42%) patients with secondary infertility, third group - 27 (43.55%) women with recurrent pregnancy loss. Absence of secretory transformation had been revealed in 27.7% women with primary infertility. In patients with secondary infertility and recurrent pregnancy loss proliferative disorders were less frequent, in11.8 and 7.4% respectively. Immunohistochemistry showed that recurrent pregnancy loss was not associated with impairment of both estrogen and progesterone receptors expression, unlike patients with primary and secondary infertility. In patients with recurrent pregnancy loss increased by 2.9 times collagen growth in endometrial stroma was detected. Conclusion. Addition of immunohistochemistry to routine histological investigation allows detection of impaired cyclic endometrial transformations during window of transformation which prevents successful implantation of blastocyst and pregnancy progression.

scholarly journals Bilateral absence of vas deferens (BAVD) a case report

2021 ◽  
Vol 11 (3) ◽  
pp. 64-66
Author(s):  
Mzyiene Mohammed
Keyword(s):  
Cystic Fibrosis ◽  
In Vitro Fertilization ◽  
Human Reproduction ◽  
Obstructive Azoospermia ◽  
Vitro Fertilization ◽  
Primary Infertility ◽  
Bilateral Absence ◽  
Reproductive Techniques ◽  
Almost All

Mutations in transmembrane conductance of cystic fibrosis (CFTR) are found in men in couples followed for infertility and for which azoospermia associated with congenital bilateral absence of the deferential canal (CBAVD) were found in men. There is a frequent association between CFTR and CBAVD abnormalities. CBAVD exists in almost all men with cystic fibrosis and causes an obstructive azoospermia that cannot be treated surgically; this poses a diagnostic and therapeutic problem because its management remains complex. However, with the use of assisted reproductive techniques (ART), in particular the aspiration of testicular or epididymic sperm, the injection of intracytoplasmic sperm and in vitro fertilization, it is possible that men with CBAVD can produce offspring. We report the case of a 32-year-old patient who consulted for primary infertility evolving over the past 5 years (genetic advice was provided). The aim of this article is to show the diagnostic and therapeutic difficulties related to this particular form of male primary infertility. Recent assisted human reproduction techniques like Intracytoplasmic Sperm Injection (ICSI) or In Vitro Fertilization (FIV) offer very good results for couple consulting for infertility of man with CBAVD.

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