scholarly journals Effects of in vitro fertilization and maternal characteristics on perinatal outcomes: a population-based study using siblings

2016 ◽  
Vol 105 (3) ◽  
pp. 590-598.e2 ◽  
Author(s):  
Jorien Seggers ◽  
Martina Pontesilli ◽  
Anita C.J. Ravelli ◽  
Rebecca C. Painter ◽  
Mijna Hadders-Algra ◽  
...  
Birth ◽  
2010 ◽  
Vol 37 (3) ◽  
pp. 184-191 ◽  
Author(s):  
Elizabeth A. Sullivan ◽  
Michael G. Chapman ◽  
Yueping A. Wang ◽  
G. David Adamson

2018 ◽  
Vol 51 ◽  
pp. 02008
Author(s):  
Irisa Zile ◽  
Inga Jefremova ◽  
Iveta Gavare

Pregnancies that occur after assisted reproduction procedures constitute high-risk pregnancies. There is a lack of sufficient epidemio-logically based data on this issue in Latvia. The aim of this study was to compare the maternal and perinatal outcomes of multiple pregnancies conceived by in vitro fertilization (IVF) in comparison with spontaneous multiple pregnancies. This retrospective cohort study (2007–2014) analysed data from population-based Medical Birth Register (MBR). There is a statistically significant increase of multiple births from IVF pregnancies – an average 2% per year (p< 0.01). Newborns of IVF multiple births have higher odds of low birth weight (OR = 1.2) and congenital anomalies (OR = 1.6). Maternity characteristics showed that mothers in the IVF group were significantly older than those in the control group (≥35 years) (OR = 2.1) and primipara births (OR = 4.1). Multiple births conceived by IVF have similar outcomes as spontaneously conceived multiples in the perinatal period, although the rates of congenital anomalies after IVF are just slightly higher than in control group.


Author(s):  
Laurence Pelage-Canlorbe ◽  
Camille Le Ray ◽  
Aurélien Seco ◽  
Coralie Chiesa-Dubruille ◽  
Marie-Hélène Bouvier-Colle ◽  
...  

2020 ◽  
Vol 113 (6) ◽  
pp. 1242-1250.e4 ◽  
Author(s):  
Barbara Luke ◽  
Morton B. Brown ◽  
Mary K. Ethen ◽  
Mark A. Canfield ◽  
Stephanie Watkins ◽  
...  

Author(s):  
Neda Razaz ◽  
Tehila Avitan ◽  
Tracy Pressey ◽  
K.S. Joseph

ABSTRACTBackgroundThere is currently insufficient evidence regarding the prognosis of multi-fetal pregnancies reduced to twins or singletons. We compared the perinatal outcomes of deliveries following fetal reduction with the perinatal outcomes of deliveries without fetal reduction. MethodsWe carried out a retrospective cohort study of all births in British Columbia between 2009 and 2013, using information from a population-based database. Comparisons were made between all women who had a fetal reduction to a twin or a singleton pregnancy with those who did not undergo a fetal reduction procedure. The outcomes of interest were preterm delivery and composite severe neonatal morbidity or perinatal mortality. Generalized estimating equations adjusting for maternal age, parity, pre-pregnancy weight, use of in vitro fertilization and baby’s sex were used to estimate odds ratios (OR) and 95% confidence intervals (CI). ResultsAmong 207,273 deliveries, 139 (0.07%) had a fetal reduction. Of these, 89 women delivered twins and 50 delivered singletons. Women who had a fetal reduction were more likely to have conceived with in vitro fertilization (77.6%) compared with those who did not (3.31%). Twins delivered after fetal reduction had lower rates of neonatal morbidity/mortality (OR 0.19, 95% CI 0.08-0.42) compared with unreduced triplets but rates similar to those of twins without a reduction procedure (OR 1.44, 95% CI 0.81-2.58). Singletons delivered after fetal reduction had non-significantly lower rates of neonatal morbidity/mortality than unreduced twins (OR 0.75, 95% CI 0.36-1.57) but significantly higher rates of neonatal morbidity/mortality (OR 3.98, 95% CI 1.91-8.30), preterm delivery and being small for gestational age than singleton pregnancies without a reduction procedure. ConclusionPerinatal outcomes of twins delivered after fetal reduction are better than those of unreduced triplets and similar to those of unreduced twins.


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