scholarly journals Can measuring the luteal phase progesterone level bridge the divide between the Atlantic?

2021 ◽  
Author(s):  
Samuel Santos-Ribeiro ◽  
Catarina Godinho ◽  
Sérgio Reis Soares
Keyword(s):  
Luteal Phase ◽  
Progesterone Level

scholarly journals Correlation between endometrial dating of luteal phase days 6 and 10 of the same menstrual cycle

1998 ◽  
Vol 116 (3) ◽  
pp. 1734-1737 ◽  
Author(s):  
Jorge Haddad Filho ◽  
Agnaldo Pereira Cedenho ◽  
Vilmon de Freitas
Keyword(s):  
Menstrual Cycle ◽  
Luteal Phase ◽  
Endometrial Thickness ◽  
Human Reproduction ◽  
Progesterone Level ◽  
Ovulatory Cycle ◽  
Plasma Progesterone ◽  
Menstrual Cycles ◽  
Infertile Couples ◽  
Study Setting

CONTEXT: Endometrial maturation, important in the diagnosis of infertile couples, has been evaluated since 1950 using the Noyes criteria. Nevertheless, there is no consensus regarding the most suitable period of the luteal phase for performing the biopsy. OBJETIVE: This study evaluated the correlation between the histological dating of two endometrial biopsies performed in the same menstrual cycle, on luteal phase days six and ten. DESIGN: Prospective study. SETTING: Human Reproduction Division of the Federal University of São Paulo, referral center. PATIENTS:Twenty-five women complaining of infertility had their menstrual cycles monitored by ultrasound and LH plasma levels, to obtain evidence of ovulation. PROCEDURES: Endometrial biopsies were performed on luteal phase days LH+6 and LH+10 (luteal phase day 1 = LH+1 = the day that follows LH peak). Dating was done according to morphometric criteria, in which an endometrium sample is considered out of phase if the minimum maturation delay is one day. On day LH+6, blood was drawn for plasma progesterone level determination. RESULTS: All patients had an ovulatory cycle (mean LH peak: 47.4 U/L; mean follicular diameter on LH peak day: 18.9 mm; mean endometrial thickness on LH peak day: 10.3 mm; mean plasma progesterone level on day LH+6: 14.4 ng/ml). 14 patients had both biopsies in phase; 5 patients had out of phase biopsies only on day LH+6; 3 had out of phase biopsies only on day LH+10 and 3 patients had out of phase biopsies on both days. McNemar's test showed no statistical difference between these data (p>33.36%). CONCLUSIONS: The correlation found between the endometrial datings suggests that biopsies performed on either of these two days are suitable for evaluation of endometrial maturation.

scholarly journals PSYCHOPHYSIOLOGICAL CHARACTERISTICS OF WOMEN IN DEPENDENCE ON THE OVARIOHORMONAL CYCLE PHASE AND PROGESTERONE ACTIVITY (PART 2)

2013 ◽  
Vol 12 (2) ◽  
pp. 257-265
Author(s):  
K. B. Muravlyova ◽  
O. I. Kuzminova ◽  
S. I. Petrova ◽  
M. V. Skoraya ◽  
O. M. Bazanova
Keyword(s):  
Menstrual Cycle ◽  
Luteal Phase ◽  
Peak Frequency ◽  
Follicular Phase ◽  
Progesterone Level ◽  
Cycle Phase ◽  
Alpha Band ◽  
Menstrual Cycle Phase ◽  
Subject Design ◽  
Alpha Peak

With the aim to identify the effects of menstrual cycle phase on the alpha EEG characteristics the 78 women aged 18–27 years were studied in a within-subject design Half the subjects began investigation at their follicular phase and half at their luteal phase (LP). The alpha peak frequency, alpha band width and power inalpha-2 range are highest, but power in alpha 1 and activation are lowest in LP that is associated with the highest saliva progesterone level.

The early luteal hormonal profile in IVF patients triggered with hCG

2020 ◽  
Vol 35 (1) ◽  
pp. 157-166 ◽  
Author(s):  
Lan N Vuong ◽  
Tuong M Ho ◽  
Toan D Pham ◽  
Vu N A Ho ◽  
Claus Yding Andersen ◽  
...  
Keyword(s):  
Ovarian Stimulation ◽  
Luteal Phase ◽  
Conflicts Of Interest ◽  
Progesterone Level ◽  
Reproductive Outcomes ◽  
Serum Progesterone ◽  
Hormonal Profile ◽  
Luteal Phase Support ◽  
Hormone Levels ◽  
Hcg Trigger

Abstract STUDY QUESTION What is the early luteal phase hormonal profile in patients undergoing ovarian stimulation for IVF/ICSI followed by hCG trigger and a freeze-all strategy without luteal phase support? SUMMARY ANSWER The peak concentration of progesterone occurred 4 days after oocyte pick-up (OPU + 4), with an average 35% fall from OPU + 4 to OPU + 6, and progesterone levels before and 12 h after hCG administration predicted levels during the early luteal phase. WHAT IS KNOWN ALREADY The luteal phase during IVF differs from that during normal cycles, particularly with respect to the serum progesterone level profile. This can cause asynchrony between the embryo and the endometrium, potentially resulting in implantation failure and poor reproductive outcomes. STUDY DESIGN, SIZE, DURATION This prospective study included 161 women with normal ovarian reserve receiving GnRH antagonist co-treatment during ovarian stimulation with FSH who were followed up to 6 days after OPU in a single IVF cycle. PARTICIPANTS/MATERIALS, SETTING, METHODS Women aged 18–42 years undergoing IVF with ovarian stimulation using FSH were included. Ovulation was triggered with recombinant hCG 250 μg. Hormone levels were determined from blood samples taken on the day of trigger, before hCG, at 12, 24 and 36 h after hCG and at 1, 2, 3, 4, 5 and 6 days after OPU. The primary endpoint was early luteal phase serum concentrations of progesterone, LH, estradiol and hCG. MAIN RESULTS AND THE ROLE OF CHANCE One outlier with a pre-hCG serum progesterone level of 11.42 ng/mL was excluded, so all analyses included 160 subjects. Progesterone levels began to increase 1 day after OPU, peaked 4 days after OPU (114 ng/mL), then declined from OPU + 5 onwards. Peak progesterone levels were at OPU + 4, OPU + 5 or OPU + 6 in 38.8, 29.4 and 13.8% of patients, respectively. Approximately two-thirds of patients had a fall in serum progesterone from OPU + 4 to OPU + 6. Pre-hCG progesterone levels correlated significantly with those at 24 h after hCG (r2 = 0.28; P < 0.001), which in turn correlated significantly with progesterone at OPU + 4 (r2 = 0.32; P < 0.001). LH peaked (4.4 IU/L) 12 h after hCG trigger, persisting for 24 h but was barely elevated compared with physiological levels. Serum estradiol peaked twice: at 24 h post-trigger and at OPU + 4. Highest hCG levels (130 mIU/mL) occurred at 24 h post-injection. The best correlations between the number of follicles ≥11 mm and serum progesterone level were seen at 24 and 36 h after hCG and OPU + 1. LIMITATIONS, REASONS FOR CAUTION The influence of different profiles of serum progesterone on reproductive outcomes could not be determined because a freeze-all strategy was used in all patients. In addition, data were not available to relate serum hormone level findings with endometrial histology or endometrial receptivity analysis to clearly identify the relationship between serum hormones and the window of implantation. WIDER IMPLICATIONS OF THE FINDINGS Detailed information about early luteal phase hormone levels could be used to optimize and individualize luteal phase support to improve reproductive outcomes. STUDY FUNDING/COMPETING INTEREST(S) This study was funded by My Duc Hospital, Ho Chi Minh City, Vietnam. All authors state that they have no conflicts of interest to disclose. TRIAL REGISTRATION NUMBER NCT02798146; NCT03174691.

scholarly journals Relationship Of FEF25-75, Pefr And SVC With Estrogen And Progesterone Level In Postmenopausal Women

1970 ◽  
Vol 6 (2) ◽  
pp. 116-121 ◽  
Author(s):  
Zinat Ara Polly ◽  
Shelina Begum ◽  
Sultana Ferdousi ◽  
Noorzahan Begum ◽  
Taskina Ali ◽  
...  
Keyword(s):  
Postmenopausal Women ◽  
Negative Correlation ◽  
Luteal Phase ◽  
Premenopausal Women ◽  
Follicular Phase ◽  
Progesterone Level ◽  
Serum Progesterone ◽  
Estrogen Level ◽  
Menopausal Women ◽  
Post Menopausal

Background: Deterioration of lung function is common in women after menopause, which may be related to very low estrogen and progesterone level. Objective: To observe FEF25-75, PEFR and SVC (slow vital capacity) values in apparently healthy postmenopausal women to find out their relationships with serum estrogen and progesterone. Methods: This study was carried out in the Department of Physiology in BSMMU, Dhaka in the year 2007. 30 healthy postmenopausal women aged 45 to 60 years and 30 healthy premenopausal women aged 20 to 30 years during their different phases of menstrual cycle were studied. Postmenopausal women were residents of Dhaka city and premenopausal subjects were medical students. FEF25-75, PEFR and SVC of all subjects were measured by a digital micro spirometer. Their estrogen and progesterone levels were estimated by Micro particle Enzyme Immunoassay (MEIA) method. Data were analyzed by Pearson’s correlation coefficient test, one way ANOVA and unpaired‘t’ test Results: The mean percentage of predicted values of FEF25-75 and PEFR were lower in postmenopausal women compared to those of follicular and luteal phases of premenopausal women but it was not significant. Measured values of SVC was Significantly (p<.001) lower in postmenopausal women compared to those of follicular and luteal phases of premenopausal women. Again Mean serum estrogen and progesterone levels were significantly (p<.001) lower in post menopausal women compared to those of follicular and luteal phases of premenopausal women. In post menopausal women, FEF25-75 was positively, PEFR and SVC were negatively correlated with progesterone level. PEFR and SVC showed positive correlattion and FEF25-75 showed negative correlation with serum estrogen level. All these correlations were statistically non significant. In premenopausal women FEF25-75 and PEFR showed positive correlation and SVC showed negative correlation with serum progesterone level. The relationships were statistically significant in luteal phase but nonsignificant in follicular phase. FEF25-75 ,PEFR and SVC were positively correlated with serum estrogen level in luteal phase but FEF25-75 and PEFR negatively correlated and SVC positively correlated with estrogen level in follicular phase. Conclusion: The outcome of this study shows FEF25-75 , PEFR and SVC may be reduced in postmenopausal women which in turn may be associated with their low progesterone and estrogen levels. DOI: http://dx.doi.org/10.3329/jbsp.v6i2.9761 JBSP 2011 6(2): 116-121

scholarly journals PSYCHOPHYSIOLOGICAL CHARACTERISTICS OF WOMEN IN DEPENDENCE ON THE OVARIOHORMONAL CYCLE PHASE AND PROGESTERONE ACTIVITY (PART 1)

2013 ◽  
Vol 12 (2) ◽  
pp. 247-256 ◽  
Author(s):  
K. B. Muravlyova ◽  
O. I. Kuzminova ◽  
S. E. Petrova ◽  
M. V. Skoraya ◽  
O. M. Bazanova
Keyword(s):  
Menstrual Cycle ◽  
Cognitive Performance ◽  
Luteal Phase ◽  
Follicular Phase ◽  
Progesterone Level ◽  
Cycle Phase ◽  
Menstrual Cycle Phase ◽  
Emotional Tension ◽  
Subject Design

With the aim to identify the effects of menstrual cycle phase on the cognitive and psycho-emotional characteristics in 78 women aged 18–27 years were studied in a within-subject design Half the subjects began during their follicular phase and half began during their luteal phase (LP). The level of psycho-emotional tension was lowest, but cognitive performance efficiency is a highest in LP that is associated with the highest saliva progesterone level.

scholarly journals Relationship of Forced Vital Capacity (FVC), Forced Expiratory Volume in First Second (FEV1)and FEV1/FVC% with Plasma Progesterone Level during Different Phases of Normal Menstrual Cycle

1970 ◽  
Vol 2 ◽  
pp. 7-12 ◽  
Author(s):  
Sultana Rokeya Mannan ◽  
Noorzahan Begum ◽  
Shelina Begum ◽  
Sultana Ferdousi ◽  
Taskina Ali
Keyword(s):  
Menstrual Cycle ◽  
Lung Function ◽  
Forced Vital Capacity ◽  
Luteal Phase ◽  
Vital Capacity ◽  
Statistical Significance ◽  
Forced Expiratory Volume ◽  
Phase Correlation ◽  
Progesterone Level ◽  
Plasma Progesterone

The present study was carried out to observe the correlation of some lung function parameters with the endogenous plasma progesterone level during different phases of menstrual cycle. The study was conducted on 30 healthy young female volunteers with age range of 20-25 years in the department of Physiology of BSMMU, Dhaka, during July 2005- June 2006. All the subjects were studied in 3 phases of menstrual cycle for 2 consecutive cycles. FVC, FEV1 , FEV1/FVC% for assessing lung function and plasma Progesterone level during each phase of menstrual cycle were measured by a portable spirometer and by ELIZA method in auto analyzer respectively. Comparison of the values between different phases were done by paired ‘t' test considering menstrual phase data as baseline due to negligible amount of progesterone detected in this phase. Correlation of FVC , FEV1 and FEV1/FVC%with Progesterone level in each 3 phases were analyzed by Pearson's correlation- coefficient test. Plasma progesterone level was much higher during luteal phase compared to those of follicular phases of both cycles (24.54ng/ml vs1.41 ng/ml; 26.56 ng/ml vs. 1.48 ng/ml). Both FVC and FEV1 were significantly higher (p<0.001) during luteal phase than those of follicular phases in both the cycles. FVC, FEV1 and FEV1/FVC%were positively correlated with plasma progesterone level but these relationships had failed to show any statistical significance. Similar to others, this study also observed increased ventilation and high endogenous progesterone level during luteal phase. Therefore increased ventilation might be related to high progesterone level during luteal phase owing to increased inspiratory muscle endurance and bronchial relaxation effect. Key words: Plasma Progesterone; Forced Vital Capacity; Forced Expiratory Volume; Menstrual cycle. DOI:10.3329/jbsp.v2i0.976 J Bangladesh Soc Physiol. 2007 Dec;(2): 7-12.

EFFECT OF HCG ON PLASMA PROGESTERONE DURING THE LUTEAL PHASE OF THE MENSTRUAL CYCLE AND DURING PREGNANCY

1972 ◽  
Vol 69 (4) ◽  
pp. 739-746 ◽  
Author(s):  
B. Runnebaum ◽  
K. Holzmann ◽  
A.-M. Bierwirth-v. Münstermann ◽  
J. Zander
Keyword(s):  
Menstrual Cycle ◽  
Early Pregnancy ◽  
Luteal Phase ◽  
Late Pregnancy ◽  
Progesterone Level ◽  
Plasma Progesterone ◽  
Peripheral Plasma ◽  
Healthy Women ◽  
Stimulation Experiments

ABSTRACT The influence of intravenous HCG infusions lasting for 2 hours on the peripheral plasma progesterone concentrations was investigated in healthy women on day 5 during the hyperthermic phase of the menstrual cycle and during week 6–19 and 31–39 of pregnancy. During the luteal phase the peripheral plasma progesterone level can be increased, on an average, up to 70 % with 5000 IU and up to 250 % with 20 000 IU. The highest plasma progesterone concentrations were reached about 8 hours after the beginning of the HCG infusion. In some experiments significantly elevated progesterone concentrations were still observed 20 hours after starting the HCG infusion. The results of intravenous HCG stimulation experiments during early pregnancy (10 000–20 000 IU) and during late pregnancy (5000–20 000 IU) showed no marked changes in the peripheral plasma progesterone concentrations.

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