scholarly journals Relationship Of FEF25-75, Pefr And SVC With Estrogen And Progesterone Level In Postmenopausal Women

1970 ◽  
Vol 6 (2) ◽  
pp. 116-121 ◽  
Author(s):  
Zinat Ara Polly ◽  
Shelina Begum ◽  
Sultana Ferdousi ◽  
Noorzahan Begum ◽  
Taskina Ali ◽  
...  
Keyword(s):  
Postmenopausal Women ◽  
Negative Correlation ◽  
Luteal Phase ◽  
Premenopausal Women ◽  
Follicular Phase ◽  
Progesterone Level ◽  
Serum Progesterone ◽  
Estrogen Level ◽  
Menopausal Women ◽  
Post Menopausal

Background: Deterioration of lung function is common in women after menopause, which may be related to very low estrogen and progesterone level. Objective: To observe FEF25-75, PEFR and SVC (slow vital capacity) values in apparently healthy postmenopausal women to find out their relationships with serum estrogen and progesterone. Methods: This study was carried out in the Department of Physiology in BSMMU, Dhaka in the year 2007. 30 healthy postmenopausal women aged 45 to 60 years and 30 healthy premenopausal women aged 20 to 30 years during their different phases of menstrual cycle were studied. Postmenopausal women were residents of Dhaka city and premenopausal subjects were medical students. FEF25-75, PEFR and SVC of all subjects were measured by a digital micro spirometer. Their estrogen and progesterone levels were estimated by Micro particle Enzyme Immunoassay (MEIA) method. Data were analyzed by Pearson’s correlation coefficient test, one way ANOVA and unpaired‘t’ test Results: The mean percentage of predicted values of FEF25-75 and PEFR were lower in postmenopausal women compared to those of follicular and luteal phases of premenopausal women but it was not significant. Measured values of SVC was Significantly (p<.001) lower in postmenopausal women compared to those of follicular and luteal phases of premenopausal women. Again Mean serum estrogen and progesterone levels were significantly (p<.001) lower in post menopausal women compared to those of follicular and luteal phases of premenopausal women. In post menopausal women, FEF25-75 was positively, PEFR and SVC were negatively correlated with progesterone level. PEFR and SVC showed positive correlattion and FEF25-75 showed negative correlation with serum estrogen level. All these correlations were statistically non significant. In premenopausal women FEF25-75 and PEFR showed positive correlation and SVC showed negative correlation with serum progesterone level. The relationships were statistically significant in luteal phase but nonsignificant in follicular phase. FEF25-75 ,PEFR and SVC were positively correlated with serum estrogen level in luteal phase but FEF25-75 and PEFR negatively correlated and SVC positively correlated with estrogen level in follicular phase. Conclusion: The outcome of this study shows FEF25-75 , PEFR and SVC may be reduced in postmenopausal women which in turn may be associated with their low progesterone and estrogen levels. DOI: http://dx.doi.org/10.3329/jbsp.v6i2.9761 JBSP 2011 6(2): 116-121

scholarly journals FVC, FEV1 and FEV1/FVC%, In Postmenopausal Women and Their Relationship with Serum Progesterone and Estrogen Level

1970 ◽  
Vol 4 (1) ◽  
pp. 7-13
Author(s):  
Zinat Ara Polly ◽  
Shelina Begum ◽  
Sultana Ferdousi ◽  
Noorzahan Begum ◽  
Taskina Ali ◽  
...  
Keyword(s):  
Menstrual Cycle ◽  
Lung Function ◽  
Postmenopausal Women ◽  
Negative Correlation ◽  
Premenopausal Women ◽  
Progesterone Level ◽  
Serum Progesterone ◽  
Cross Sectional ◽  
Positive Correlation ◽  
Estrogen Level

Background: Exacerbation of asthma associated with worsening of lung function has been reported in women after menopause. The relationship between lung function and female sex hormones has been documented in postmenopausal women. Objective: To observe FVC, FEV1, FEV1/FVC%, serum estrogen and progesterone levels in apparently healthy postmenopausal women to find out their interrelationships. Methods: This cross sectional study was carried out in the Department of Physiology, from 1st January 17to 31st December 2007 in BSMMU, Dhaka. 30 postmenopausal women aged 45 to 60 years and 30 premenopausal women aged 20 to 30 years during different phases of menstrual cycle were studied. FVC, FEV1 and FEV1/FVC%, were measured by RMS computer based Spirometer. Estrogen and progesterone levels were estimated by Micro particle Enzyme Immunoassay (MEIA) method. Data were analyzed by Pearson's correlation coefficient test, one way ANOVA and unpaired‘t' test. Results: The mean percentage of predicted values of FVC and FEV1 were significantly (p<.001) lower in postmenopausal women compared to those of follicular and luteal phases of premenopausal women. Mean serum estrogen and progesterone levels were significantly lower in postmenopausal women compared to any phases of menstrual cycle of premenopausal women. In postmenopausal women, FVC, FEV1 showed positive correlation with progesterone but negative with estrogen level.FEV1/ FVC% Showed negative correlation with both serum estrogen and progesterone level. All these correlations were statistically non significant. In premenopausal women FEV1 and FEV1/FVC% showed positive correlation and FVC showed negative correlation with serum estrogen level in follicular phase and FVC, FEV1 showed positive and FEV1/FVC% showed negative correlation with serum estrogen level in luteal phase. Again FVC, FEV1 and FEV1/FVC% showed positive correlation with serum progesterone level in follicular and luteal phases of menustrual cycle. Conclusion: The out come of this study shows FVC, FEV1 may be reduced in postmenopausal women which in turn may be associated with low progesterone and estrogen levels. Key words: Menopause, Lung function, Estrogen, Progesterone. DOI: 10.3329/jbsp.v4i1.4063 J Bangladesh Soc Physiol. 2009 June; 4(1): 7-13

scholarly journals COMPONENTS OF A HEALTHFUL DIET ARE ASSOCIATED WITH WAIST CIRCUMFERENCE AMONG PRE- AND POSTMENOPAUSAL WOMEN

2019 ◽  
Vol 3 (Supplement_1) ◽  
pp. S55-S55
Author(s):  
Lisa M Troy ◽  
Sarah Witkowski
Keyword(s):  
Waist Circumference ◽  
Postmenopausal Women ◽  
Premenopausal Women ◽  
Visceral Adiposity ◽  
Omega 3 ◽  
Refined Grains ◽  
Increased Risk ◽  
Menopausal Women ◽  
Post Menopausal ◽  
Dark Green

Abstract After menopause, women are at increased risk of diabetes and cardiovascular disease. A contributing factor to increased risk may be weight gain, especially visceral adiposity. Diet plays a role in maintaining weight at all ages but less is known about the specific contributions of a healthful dietary pattern after menopause. Therefore, we evaluated associations between diet and WC as a measure of visceral adiposity. We compared 869 pre- (aged 35-45 years) and 353 post-menopausal (aged 40-65 years) women from NHANES III (1988-94). Women were pre-menopausal if they self-reported menses in the past 2 months and postmenopausal if they reported no menses in past 12 months and were aged &gt; 40 years. Compared to premenopausal women, postmenopausal women consumed fewer Calories (-200 kcal/d) and had a higher mean waist circumference (+4.43 cm, p=0.007), after adjusting for age, race-ethnicity, height, physical activity, and smoking. Higher intakes of dark green vegetables (p=0.03) and lower intakes of potatoes (p=0.03), refined grains (p=0.001), and meats (p=0.04) were associated with lower WC for all women. Higher intakes of nuts and seeds and fish high in Omega-3 fatty acids were associated with smaller WC while higher intakes of poultry and dairy products were associated with higher WC in post- but not pre-menopausal women. Our findings generally support a diet high in nuts and seeds, dark green vegetables, and fish, and low in potatoes, refined grains, and meats. After menopause it may be important to incorporate fatty fish, nuts and seeds into the diet for lower visceral adiposity.

scholarly journals Understanding the Impact of Periodontal Status in Pre & Post-Menopausal Women with Generalized Chronic Periodontitis and Osteoporosis: A Cross Sectional Study

2017 ◽  
Vol 9 (3) ◽  
pp. 204
Author(s):  
Sameena Sultana
Keyword(s):  
Postmenopausal Women ◽  
Chronic Periodontitis ◽  
Premenopausal Women ◽  
Cross Sectional Study ◽  
Monthly Basis ◽  
Cross Sectional ◽  
Periodontal Status ◽  
Menopausal Women ◽  
Post Menopausal ◽  
The Impact

Chronic periodontitis and osteoporosis are two interconnected medical issues, which usually develops complications in the general public. However, public is mostly unaware of their periodontal status. The research study has aimed to understand the impact of periodontal status among pre and post-menopausal women, suffering from periodontitis and osteoporosis. A cross-section approach has been selected for data collection. 70 patients were selected from the outpatient department of SRM dental college in Chennai. SPSS version 20 has been used for statistical analysis. Postmenopausal women have shown statistically significant poor periodontal status as compared to premenopausal women. Similarly, it has also been evaluated that osteoporosis played a progressive role among postmenopausal women for developing periodontitis. The study leads to the conclusion that pre and post-menopausal women must undergo a periodontal assessment on a monthly basis for developing outcomes related to the risk of fractures. Parameters are closely connected with the levels of calcium according to the tests and assessments.

EVALUATION OF SERUM TSH IN PREMENOPAUSAL AND POST MENOPAUSAL WOMEN IN A TERTIARY CARE HOSPITAL

2021 ◽  
pp. 30-33
Author(s):  
Elvis Vishal Saurabh Saurabh Dadel ◽  
Tarique Aziz ◽  
Asha Premlata Omega Oraon
Keyword(s):  
Statistical Analysis ◽  
Postmenopausal Women ◽  
Tertiary Care ◽  
Premenopausal Women ◽  
Reproductive Age ◽  
P Value ◽  
Care Hospital ◽  
Menopausal Women ◽  
Post Menopausal ◽  
Serum Tsh

Objective- To evaluate and compare the level of TSH in premenopausal women (reproductive age group) and post-menopausal women. Material And Methods- The study was carried out on 100 premenopausal and 100 post-menopausal women attending Out Patient Departments at RIMS, Ranchi, during the period of January 2018- October 2019. Study Design: - Observational Study. Statistics- Statistical analysis was done using SPSS software. The data were represented by counts, percentage and mean ± standard deviation. Statistical analysis of TSH was done by t-test to compare these parameters in premenopausal and post-menopausal women. A p-value of <0.05 was considered statistically signicant. Result- In the present study, we found that the mean serum TSH level in postmenopausal women 2.72 (± 1.06) uIU/ml was comparatively higher than premenopausal women 2.29 (±1.12) uIU/ml and the difference between the two was statistically signicant (p<0.001). Conclusion- Thyroid hormones play an important role in maintaining normal reproductive behaviour by directly effecting on gonadal function and indirectly interacting with sex hormone binding protein. Alteration of thyroid hormone level leads to menstrual irregularities and infertility. The present study clearly demonstrated that there was signicant increase in TSH levels in post-menopausal women and was statistically signicant. Thus, it proved that postmenopausal women are more prone to subclinical hypothyroidism.

scholarly journals An epidemiological study to assess bone mineral density and its association with contributing factors among premenopausal and postmenopausal women in selected villages of District Shimla, Himachal Pradesh, India

2018 ◽  
Vol 7 (2) ◽  
pp. 487 ◽  
Author(s):  
Nancy Garg ◽  
Viji Mol G. ◽  
Deepika Sethi
Keyword(s):  
Bone Loss ◽  
Bone Mass ◽  
Postmenopausal Women ◽  
Economic Status ◽  
Premenopausal Women ◽  
Research Approach ◽  
Contributing Factors ◽  
Mineral Density ◽  
Menopausal Women ◽  
Post Menopausal

Background: Development of peak bone mass and premenopausal bone loss is determined by the menstrual status of women. Decline in bone mass with age becomes accelerated during menopause. Menopausal bone loss refers to the accelerated bone loss that occurs during the BM) of premenopausal and post-menopausal women, to identify the contributing factors associated with BMD among pre and post-menopausal women, to compare the level of BMD and the contributing factors of pre-menopausal women with post-menopausal women.Methods: It was quantative research approach and epidemiological analytic research design was used. Total enumeration technique was adopted in this study.Results: Analysis of data was done in accordance with the objectives of the study. Findings show that among premenopausal women 45.10% of the women had osteopenia and 8.20% of the women had osteoporosis, among postmenopausal women 50.00% of the women had oestriopenic and 41.2% of the women had osteoporosis. The analysis shows that factors such as BMI, Health status, life style, age, economic status and dietary patter plays important role to accelerate the level of T-score more than -1 in both group either premenopausal women or post-menopausal women. It shows the significance at the level of p<0.001.Conclusions: The study was completed in July 2016, concludes that there are many factors that can lead to have risk of osteoporosis related fracture. As age is increased the risk is also increased to get the fracture. Every woman can go for screening of BMD test to control the risk of fracture.

scholarly journals Effect of Estrogen on Serum Total Cholesterol and Triglyceride Levels in postmenopausal women

2017 ◽  
Vol 26 (1) ◽  
pp. 25-31 ◽  
Author(s):  
Nahid Yeasmin ◽  
Qazi Shamima Akhter ◽  
Sayeeda Mahmuda ◽  
Sharrmin Nahar ◽  
Rukhshana Rabbani ◽  
...  
Keyword(s):  
Cardiovascular Diseases ◽  
Total Cholesterol ◽  
Postmenopausal Women ◽  
Negative Correlation ◽  
Premenopausal Women ◽  
Serum Total Cholesterol ◽  
Control Group ◽  
Cross Sectional ◽  
Medical College ◽  
Estrogen Level

Background: Hyperlipidemia is a major risk factor for cardiovascular diseases in postmenopausal women. Increased incidence of cardiovascular diseases in postmenopausal women may be due to hyperlipidemia caused by lower level of estrogen hormone.Objectives: The study was carried out to observe the association of serum estrogen with total cholesterol (TC) and triglyceride (TG) levels in postmenopausal women.Methods: This cross sectional study was conducted in the Department of Physiology, Dhaka Medical College, Dhaka, during the period of January to December 2011. A total of 90 females were selected from different areas of Dhaka city. Among them, 60 postmenopausal women with age ranging from 50 to 60 years were taken as study group and 30 apparently healthy premenopausal women with age ranging from 20 to 30 years were included as control group for comparison. The study parameters total cholesterol and triglyceride were estimated by enzymatic method in both groups. Serum estrogen level was estimated by Radioimmunoassay ( RIA) method in order to assess the hormonal level of both groups. Data was analyzed by Unpaired Student’s t- test and Pearson’s correlation co-efficient (r) test as applicable.Results: In this study, the mean serum TC level was higher in postmenopausal women than those of premenopausal women and result was statistically significant. The level of mean serum TG was significantly (p<0.001) higher in postmenopausal women in comparison to those of premenopausal women. In postmenopausal women serum estrogen level was lower than premenopausal women and serum estrogen level showed negative correlation with TC level. .Again serum TG level also showed negative correlation with serum estrogen level. All these correlation were statistically non-significant.Conclusion: From the results of the present study it may be concluded that the serum total cholesterol and triglyceride levels are significantly higher in postmenopausal women that may be due to low level of estrogen.J Dhaka Medical College, Vol. 26, No.1, April, 2017, Page 25-31

scholarly journals Correlation of Serum Level of Progesterone with Peak Expiratory Flow Rate (PEFR) in Different Phases of Menstrual Cycle

1970 ◽  
Vol 3 (1) ◽  
pp. 6-9 ◽  
Author(s):  
Sultana Rokeya Mannan ◽  
Noorjahan Begum
Keyword(s):  
Menstrual Cycle ◽  
Luteal Phase ◽  
Young Female ◽  
Follicular Phase ◽  
Progesterone Level ◽  
Elisa Method ◽  
Serum Progesterone ◽  
Plasma Progesterone ◽  
Menstrual Cycles ◽  
Medical University

The present study has been carried out to observe the correlation of endogenous serum progesterone level with PEFR during luteal and follicular phases of two consecutive menstrual cycles. This study was conducted on 30 healthy young female volunteers with age ranges of 20- 24 years in the Department of Physiology of Bangladesh Shikh Mujib Medical University (BSMMU), Dhaka during July, 2005 to June, 2006. Serum progesterone level and PEFR of all subjects during all three phases of menstrual cycles were measured by ELISA method and a portable Spirometer respectively. Plasma progesterone level is highest during luteal phase; which is about 24 fold higher than that at follicular phases. (24.54ng/ml vs 1.4ng/ml). PEFR was positively correlated with progesterone level, but statistically not significant and it was significantly higher during luteal phase than follicular phase. This result indicates that changes in the pulmonary function occurred during different phases of menstrual cycle and this is more marked during luteal phase. DOI: http://dx.doi.org/10.3329/akmmcj.v3i1.10105 AKMMCJ 2012; 3(1): 6-9

scholarly journals Role of Triple Assessment of Breast Lump in Premenopausal and Postmenopausal Women -A Comparative and Descriptive Study

2020 ◽  
Vol 11 (SPL4) ◽  
pp. 1390-1397
Author(s):  
Devi Priya S ◽  
Lakshmana R ◽  
Abhilash M ◽  
Sujeeth A ◽  
Govinda Raju C
Keyword(s):  
Postmenopausal Women ◽  
Invasive Ductal Carcinoma ◽  
Ductal Carcinoma ◽  
Premenopausal Women ◽  
Breast Disease ◽  
Breast Lump ◽  
Triple Assessment ◽  
Menopausal Women ◽  
Malignant Breast ◽  
Post Menopausal

Triple assessment of breast is based on clinical examination, histological and radiological study where in our study, the pattern of breast swelling in a premenopausal and postmenopausal woman was compared. A total of 150 female patients with palpable breast lump went through clinical examination, FNAC, USG breast while mammogram & core needle biopsy was done in selected patients. Histopathological examination of the specimen was done for all post-operative patients. Benign & malignant breast lesion accounted for 82(54.6%) & 68(45.3%) respectively. Based on the incidence of benign breast lump & malignant breast lump among pre menopausal women, it was 79% & 21% respectively while in post menopausal women it was  21.9% & 78.1%. The most common type of breast lump among the pre and post menopausal women was fibroadenoma 56.9% & Invasive ductal carcinoma 59.3% respectively. The most common benign breast lump & malignant breast lesion based on the histological pattern among the premenopausal women was fibroadenoma 72% & Invasive ductal carcinoma 50% while in postmenopausal women it was fibroadenosis 71.4% & Invasive Ductal Carcinoma 76%. Based on the hormonal status(ER/PR) of pre and postmenopausal women positivity was seen majorly in post menopausal women 82.3% compared to premenopausal women 17.7%. In our study, the malignant breast disease was more common in post menopausal, while benign breast disease was common in pre menopausal women.  Triple assessment in evaluating a breast lump is per se a reliable & valid tool in the armamentarium of treating clinician with very high diagnostic accuracy.

Reproducible assessment of vaginal and rectal mucosal and skin blood flow: laser doppler fluximetry of the pelvic microcirculation

2000 ◽  
Vol 98 (2) ◽  
pp. 201-207 ◽  
Author(s):  
A. V. EMMANUEL ◽  
M. A. KAMM ◽  
R. W. BEARD
Keyword(s):  
Blood Flow ◽  
Menstrual Cycle ◽  
Postmenopausal Women ◽  
Luteal Phase ◽  
Vascular Reactivity ◽  
Rectal Mucosa ◽  
Premenopausal Women ◽  
Follicular Phase ◽  
Laser Doppler ◽  
Head Up Tilt

Pelvic venous congestion is a common cause of chronic pelvic pain in women of reproductive age. Although this condition represents a functional disturbance of the pelvic circulation which is related to the menstrual cycle, its aetiology remains unknown. Indirect techniques demonstrate that the vasoconstrictive reflex response of the microcirculation of the foot to a rise in venous pressure is attenuated throughout the menstrual cycle. We wished to develop a simple and non-invasive direct measure of pelvic blood flow to aid diagnosis of this condition. Laser doppler blood flux measurements of the skin of the big toe and of the vaginal and rectal mucosa in the follicular and luteal phases of the menstrual cycle in 12 healthy asymptomatic premenopausal women (mean age 30 years) with regular cycles and in four healthy asymptomatic postmenopausal women (mean age 59 years) were carried out both in the supine position and in response to 40° head-up tilt. The coefficient of variation of resting vaginal flux was lower for measurements in postmenopausal women (0.04) and in premenopausal women in the follicular phase (0.07) compared with those in the luteal phase (0.16). At rest, vaginal blood flow was higher than rectal and skin flux in both premenopausal and postmenopausal women. In the follicular phase a decrease in flow was observed in response to head-up tilt in the skin (-32.0%), vagina (-34.3%) and rectum (-9.4%). In the luteal phase this reflex was attenuated at these three sites (-8.6%, +6.7% and +7.4% respectively). There were no significant reflex changes in postmenopausal women. Thus laser doppler fluximetry is a reproducible method for comparing the flux of blood in the microcirculation of the skin and of the vaginal and rectal mucosa. The skin is the least sensitive site for testing vascular reactivity in response to cyclical changes. The vaginal and rectal microcirculations are the most sensitive sites for testing visceral cyclical reactivity, and have the advantage of direct anatomical relevance. The follicular phase of the menstrual cycle is associated with greatest vascular reactivity and is the most appropriate phase during which to test for abnormal vascular responses.

scholarly journals A Comparative Study of Lipid Profile and Atherogenic Index of Plasma Among the Pre and Post-Menopausal Women

2018 ◽  
Vol 9 (1) ◽  
pp. 44-49 ◽  
Author(s):  
Sadia Khanduker ◽  
Rumana Ahmed ◽  
Mafruha Nazneen ◽  
Anawarul Alam ◽  
Farhana Khondokar
Keyword(s):  
Risk Factor ◽  
Lipid Profile ◽  
Independent Risk Factor ◽  
Cardiovascular Health ◽  
Premenopausal Women ◽  
Atherogenic Index ◽  
Mathematical Methods ◽  
Atherogenic Index Of Plasma ◽  
Menopausal Women ◽  
Post Menopausal

Background: Menopausal health in our environment has received little attention. As a independent risk factor for dyslipidemia, the degree and pattern of derangement, though difficult to assess may adversely affect the cardiovascular health of our women.Objectives: To estimate the serum lipid profile and the atherogenic index of plasma among the pre and post- menopausal women.Materials and Methods: After an overnight fasting blood samples were collected from a group of 339 women, 140 premenopausal aged between 25-50 years and 199 postmenopausal aged between 51-70 years. Serum total cholesterol (TC), triglycerides (TG) and HDL-cholesterol were estimated by enzymatic methods and LDL-cholesterol by established mathematical methods. Atherogenic index of plasma (AIP) were calculated by using the formula (logTG/HDL-C). Statistical analysis was carried out in the two groups using the unpaired t test. Results were expressed as mean±SD. P values <0.05 were considered to be statistically significant.Results: There were statistically significant increase in serum TC (191.21±45.50 mg/dl), TG (185.83± 111.83 mg/dl) and LDL-C (118.71±38.48 mg/dl) in post-menopausal women. Their HDL-C level (38.67±10.00mg/dl) was significantly decreased. The calculated atherogenic index of plasma (AIP) was significantly higher (0.63±0.27) in post-menopausal women as compared to that in premenopausal women (0.50±0.29).Conclusion: Menopause leads to changes in lipid profile. By elevating LDL and the reduction of cardioprotective HDL is an indication that menopause is an independent risk factor for developing cardiovascular disease. These changes are caused by loss of cardio-protective effect of oestrogen.Anwer Khan Modern Medical College Journal Vol. 9, No. 1: Jan 2018, P 44-49

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