Family size and duration of fertility in female cancer survivors: a population-based analysis

This study investigated factors associated with successful return to work for cancer survivors in accordance with the Americans with Disabilities Act. A focus group was held with seven female cancer survivors. Participants discussed return-to-work issues following a cancer diagnosis. Factors such as coworker support and job flexibility improved their experiences, whereas coworker and supervisor ignorance about cancer and lack of support made returning to work more stressful. Participants discussed personal, environmental, and cancer-related factors that influenced their experiences with returning to work following a cancer diagnosis. Knowledge of factors that support employees helps occupational health nurses ease their transition, and may improve quality of life for employees. Physicians and health care provider teams may play a critical role in the employees' positive evaluation of their recovery process. This pilot study serves as a basis for a larger, population-based study.

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Adverse birth outcomes in adolescent and young adult female cancer survivors: a nationwide population-based study

British Journal of Cancer ◽

10.1038/s41416-019-0712-2 ◽

2020 ◽

Vol 122 (6) ◽

pp. 918-924

Author(s):

Wei-Heng Kao ◽

Chang-Fu Kuo ◽

Meng-Jiun Chiou ◽

Yu-Cheng Liu ◽

Chun-Chieh Wang ◽

...

Keyword(s):

Young Adult ◽

Cancer Survivors ◽

Birth Outcomes ◽

Adult Female ◽

Population Based ◽

Adolescent And Young Adult ◽

Adverse Birth Outcomes ◽

Population Based Study ◽

Female Cancer Survivors

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Relation between platelet coagulant and vascular function, sex-specific analysis in adult survivors of childhood cancer compared to a population-based sample

Scientific Reports ◽

10.1038/s41598-019-56626-1 ◽

2019 ◽

Vol 9 (1) ◽

Author(s):

Marina Panova-Noeva ◽

Bianca Wagner ◽

Markus Nagler ◽

Natalie Arnold ◽

Jürgen H. Prochaska ◽

...

Keyword(s):

Arterial Hypertension ◽

Cancer Survivors ◽

Childhood Cancer ◽

Vascular Function ◽

Adult Survivors ◽

Population Based ◽

Peak Height ◽

Stiffness Index ◽

Increased Risk ◽

Female Cancer Survivors

AbstractFemale sex is a risk factor for long-term adverse outcome in cancer survivors, however very little is known for the underlying pathophysiological mechanisms rendering the increased risk. This study investigated sex-specifically the relation between thrombin generation (TG) with and without presence of platelets and vascular function in 200 adult survivors of a childhood cancer compared to 335 population-based control individuals. TG lag time, peak height and endogenous thrombin potential (ETP) measured in presence and absence of platelets were correlated to reflection index (RI) and stiffness index (SI). A sex-specific correlation analysis showed a negative relation in female survivors for platelet-dependent peak height and/or ETP and RI only. An age adjusted linear regression model confirmed the negative association between RI and platelet-dependent ETP (beta estimate: −6.85, 95% confidence interval: −12.19,−1.51) in females. Adjustment for cardiovascular risk factors resulted in loss of the association, whereby arterial hypertension and obesity showed the largest effects on the observed association. No other relevant associations were found in male and female cancer survivors and all population-based controls. This study demonstrates a link between platelet coagulant and vascular function of resistance vessels, found in female cancer survivors, potentially mediated by the presence of arterial hypertension and obesity.

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Evaluation of health perceptions and healthcare utilization among population-based female cancer survivors and cancer-free women

Cancer Causes & Control ◽

10.1007/s10552-021-01498-y ◽

2021 ◽

Author(s):

Kate E. Dibble ◽

Maneet Kaur ◽

Junrui Lyu ◽

Avonne E. Connor

Keyword(s):

Cancer Survivors ◽

Healthcare Utilization ◽

Population Based ◽

Health Perceptions ◽

Free Women ◽

Female Cancer Survivors

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Perinatal risks in female cancer survivors: A population-based analysis

PLoS ONE ◽

10.1371/journal.pone.0202805 ◽

2018 ◽

Vol 13 (8) ◽

pp. e0202805 ◽

Cited By ~ 9

Author(s):

Anne-Lotte L. F. van der Kooi ◽

David H. Brewster ◽

Rachael Wood ◽

Sian Nowell ◽

Colin Fischbacher ◽

...

Keyword(s):

Cancer Survivors ◽

Population Based ◽

Female Cancer Survivors ◽

Perinatal Risks

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Cohort profile: an observational longitudinal data collection of health aspects in a cohort of female cancer survivors with a history of pelvic radiotherapy—a population-based cohort in the western region of Sweden

BMJ Open ◽

10.1136/bmjopen-2021-049479 ◽

2021 ◽

Vol 11 (7) ◽

pp. e049479

Author(s):

Linda Åkeflo ◽

Gail Dunberger ◽

Eva Elmerstig ◽

Viktor Skokic ◽

Gunnar Steineck ◽

...

Keyword(s):

Data Collection ◽

Longitudinal Data ◽

Cancer Survivors ◽

Late Effects ◽

Population Based ◽

Study Cohort ◽

Western Region ◽

Pelvic Radiotherapy ◽

Female Cancer Survivors

PurposeThe study ‘Health among women after pelvic radiotherapy’ was conducted in response to the need for more advanced and longitudinal data concerning long-term radiotherapy-induced late effects and chronic states among female cancer survivors. The objective of this paper is to detail the cohort profile and the study procedure in order to provide a sound basis for future analyses of the study cohort.ParticipantsSince 2011, and still currently ongoing, participants have been recruited from a population-based study cohort including all female patients with cancer, over 18 years of age, treated with pelvic radiotherapy with curative intent at Sahlgrenska University Hospital in Gothenburg, in the western region of Sweden, which covers 1.7 million of the Swedish population. The dataset presented here consists of baseline data provided by 605 female cancer survivors and 3-month follow-up data from 260 individuals with gynaecological, rectal or anal cancer, collected over a 6-year period.Findings to dateData have been collected from 2011 onwards. To date, three studies have been published using the dataset reporting long-term radiation-induced intestinal syndromes and late adverse effects affecting sexuality, the urinary tract, the lymphatic system and physical activity. These projects include the evaluation of interventions developed by and provided in a nurse-led clinic.Future plansThis large prospective cohort offers the possibility to study health outcomes in female pelvic cancer survivors undergoing a rehabilitation intervention in a nurse-led clinic, and to study associations between demographics, clinical aspects and long-term late effects. Analysis focusing on the effect of the interventions on sexual health aspects, preinterventions and postinterventions, is currently ongoing. The cohort will be expanded to comprise the entire data collection from 2011 to 2020, including baseline data and data from 3-month and 1-year follow-ups after interventions. The data will be used to study conditions and treatment-induced late effects preintervention and postintervention.

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