Can pressure-induced cell inactivation be related to cell volume compression? A case study for Saccharomyces cerevisiae

2013 ◽  
Vol 54 (1) ◽  
pp. 738-744 ◽  
Author(s):  
Marwen Moussa ◽  
Vincent Espinasse ◽  
Jean-Marie Perrier-Cornet ◽  
Patrick Gervais
2016 ◽  
Vol 63 (2) ◽  
Author(s):  
Mateusz Molon ◽  
Renata Zadrag-Tecza

The yeast Saccharomyces cerevisiae has long been used as a model organism for studying the basic mechanisms of aging. However, the main problem with the use of this unicellular fungus is the unit of "longevity". For all organisms, lifespan is expressed in units of time, while in the case of yeast it is defined by the number of daughter cells produced. Additionally, in yeast the phenotypic effects of mutations often show a clear dependence on the genetic background, suggesting the need for an analysis of strains representing different genetic backgrounds. Our results confirm the data presented in earlier papers that the reproductive potential is strongly associated with an increase in cell volume per generation. An excessive cell volume results in the loss of reproductive capacity. These data clearly support the hypertrophy hypothesis. The time of life of all analysed mutants, with the exception of sch9D, is the same as in the case of the wild-type strain. Interestingly, the 121% increase of the fob1D mutant's reproductive potential compared to the sfp1D mutant does not result in prolongation of the mutant's time of life (total lifespan).


2009 ◽  
Vol 160 (6) ◽  
pp. 380-388 ◽  
Author(s):  
Libera Lo Presti ◽  
Lorenzo Cerutti ◽  
Michel Monod ◽  
Philippe M. Hauser

2008 ◽  
Vol 10 (4) ◽  
pp. 481-488 ◽  
Author(s):  
Renata Zadrag-Tecza ◽  
Magdalena Kwolek-Mirek ◽  
Grzegorz Bartosz ◽  
Tomasz Bilinski

2021 ◽  
pp. 016224392110354
Author(s):  
Erika Amethyst Szymanski

This paper concerns how digitizing biological resources enables disentangling information technologies from biological bodies and, thus, from response-abilities among creatures from which they are derived. Extracting (digital) information from (biological) bodies makes it possible to stabilize, freeze, circulate, and control that information independently from creaturely activities—multiplying, not subtracting from the originating material. Such extractions tend to attenuate human interdependencies with other creatures even while expanding the scope of their utility as resources, to the effect of limiting those who have a stake in their development to humans alone. Where conventional natural resource extraction does violence to places and those interdependent with them, digital resource extractions may instead do violence to human capacities to recognize and act on multispecies interdependencies. Here, I argue that choosing to realize connections among organisms and organismal resources makes it possible to envision how creatures may be stakeholders in their own development, with joined ethical and epistemic consequences. I trace that possibility through a case study of the essential laboratory yeast Saccharomyces cerevisiae via the physical metaphor of snowflake yeast, an S. cerevisiae variant that maintains multicellular connections as it reproduces.


2020 ◽  
Vol 45 (5) ◽  
pp. 143-151
Author(s):  
O. O. Adelusi ◽  
R. M. Akinbode ◽  
K. O. Adebayo ◽  
K. M. Stephen ◽  
A. S. Oluwasegun

A study was carried out to evaluate the effect of inclusion of yeast (Saccharomyces cerevisiae) on the performance, rumen characteristics and blood profile of West African dwarf (WAD) goats. Four (4) dietary treatments were prepared by adding 0 g, 0.5 g, 1.0 g and 1.5 g yeast to concentrate feed. Twelve (12) WAD goats with an average live weight of 10.17±0.53 kg were allocated to the four treatment lots in a completely randomised design and used in a feeding trial that lasted 70 days. Concentrate was fed at 3% of body weight while Panicum maximum as the basal diet was ad libitum. Data were collected on nutrient intake, rumen fermentation and microbial ecology, blood profile and then analysed using one-way analysis of variance. Results showed that inclusion of yeast did not affect (P>0.05) nutrient intake, rumen fermentation of WAD goats. Bacteria and fungi population were also not affected (P>0.05) by the inclusion of yeast, however there was an increase (P<0.05) in 9 9 pr otozoa from 0.73× 10 (control) to 1.33× 10 (1.0g yeast). Packed cell volume (PCV) of goats decreased (P<0.05) when goats were fed 1.5g yeast (20.93%) compared to control (24.37%). It can be concluded that addition of yeast to the diets of WAD goats did not affect their overall performance, increased population of rumen protozoa and reduced blood packed cell volume.


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