In vitro evaluation of novel (nanoparticle) oral delivery systems allow selection of gut immunomodulatory formulations

2021 ◽  
Author(s):  
Ahmed Attaya ◽  
Kimberly Veenstra ◽  
Michael D. Welsh ◽  
Mukhtar Ahmed ◽  
Nessim Torabi-Pour ◽  
...  
Keyword(s):  
Oral Delivery ◽  
Delivery Systems ◽  
In Vitro Evaluation ◽  
Oral Delivery Systems ◽  
Selection Of

In vitro evaluation of glycol chitosan based formulations as oral delivery systems for efflux pump inhibition

2017 ◽  
Vol 166 ◽  
pp. 73-82 ◽  
Author(s):  
Delia Mandracchia ◽  
Adriana Trapani ◽  
Giuseppe Tripodo ◽  
Maria Grazia Perrone ◽  
Gaetano Giammona ◽  
...  
Keyword(s):  
Oral Delivery ◽  
Efflux Pump ◽  
Delivery Systems ◽  
Glycol Chitosan ◽  
In Vitro Evaluation ◽  
Efflux Pump Inhibition ◽  
Oral Delivery Systems

In vitro Evaluation of Arabinoxylan Gels as an Oral Delivery System for Insulin

2012 ◽  
Vol 1487 ◽  
Author(s):  
E. Carvajal-Millan ◽  
C. Berlanga-Reyes ◽  
A. Rascón-Chu ◽  
A. L. Martínez-López ◽  
J. A. Márquez-Escalante ◽  
...  
Keyword(s):  
Diffusion Coefficient ◽  
Apparent Diffusion Coefficient ◽  
Delivery System ◽  
Oral Delivery ◽  
Delivery Systems ◽  
Oral Delivery System ◽  
Apparent Diffusion ◽  
Oral Delivery Systems ◽  
Hydrolysis Of

ABSTRACTArabinoxylan gels are receiving increasing attention as oral delivery systems of biomolecules for therapeutic purposes. The aim of this research was to evaluate arabinoxylan gels as an oral delivery system for insulin, representing a painless therapy for diabetics. Gels at two concentrations of arabinoxylan were prepared (2.5 and 3.5 % w/v). One concentration of insulin (0.05 % w/v) entrapped in the arabinoxylan gels was investigated. At the end of gelation elasticity (G’) values were 11 and 20 for gels at 2.5 and 3.5% (w/v) in arabinoxylan, respectively. The presence of insulin in the gels did not affect the values of G’. The apparent diffusion coefficient for insulin decreased from 1.30 x 10-7 to 1.09 x 10-7 cm2/s when the concentration of arabinoxylan in the gel increased from 2.5 to 3.5% (w/v). The percentage of proteolysis for insulin entrapped in the gels at 2.5 and 3.5% in arabinoxylan (w/v) were 35 and 17%, respectively, in relation to 100% hydrolysis of insulin in solution. Results indicate that arabinoxylan gels could be potential candidates as oral delivery systems for insulin.

Development of antioxidant gliadin particle stabilized Pickering high internal phase emulsions (HIPEs) as oral delivery systems and the in vitro digestion fate

2018 ◽  
Vol 9 (2) ◽  
pp. 959-970 ◽  
Author(s):  
F. Z. Zhou ◽  
T. Zeng ◽  
S. W. Yin ◽  
C. H. Tang ◽  
D. B. Yuan ◽  
...  
Keyword(s):  
Lipid Oxidation ◽  
Chemical Stability ◽  
Oral Delivery ◽  
In Vitro Digestion ◽  
Delivery Systems ◽  
Algal Oil ◽  
Internal Phase ◽  
First Time ◽  
Oral Delivery Systems

In this paper, we demonstrate for the first time the use of gliadin particles to structure algal oil (rich in DHA) and to exert chemical stability against lipid oxidation via the Pickering high internal phase emulsion (HIPE) strategy.

In vitro assessment of archaeosome stability for developing oral delivery systems

2000 ◽  
Vol 194 (1) ◽  
pp. 39-49 ◽  
Author(s):  
Girishchandra B Patel ◽  
Brian J Agnew ◽  
Lise Deschatelets ◽  
L.Perry Fleming ◽  
G.Dennis Sprott
Keyword(s):  
Oral Delivery ◽  
Delivery Systems ◽  
In Vitro Assessment ◽  
Oral Delivery Systems

scholarly journals Addendum: Gilani et al. Formulation and Optimization of Nano Lipid Based Oral Delivery Systems for Arthritis. Coatings 2021, 11, 548

Coatings ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 781
Author(s):  
Sadaf Jamal Gilani ◽  
May Nasser Bin-Jumah ◽  
Syed Sarim Imam ◽  
Sultan Alshehri ◽  
Mohammed Asadullah Jahangir ◽  
...  
Keyword(s):  
Oral Delivery ◽  
Delivery Systems ◽  
Oral Delivery Systems

The authors wish to make the following corrections to this paper [...]

The importance of gastrointestinal uptake of particles in the design of oral delivery systems

1995 ◽  
Vol 18 (1) ◽  
pp. 5-22 ◽  
Author(s):  
E.C. Lavelle ◽  
S. Sharif ◽  
N.W. Thomas ◽  
J. Holland ◽  
S.S. Davis
Keyword(s):  
Oral Delivery ◽  
Delivery Systems ◽  
Gastrointestinal Uptake ◽  
Oral Delivery Systems
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