scholarly journals Influence of concentration gradient on detonation re-initiation in a bifurcated channel

Fuel ◽  
2022 ◽  
Vol 307 ◽  
pp. 121895
Author(s):  
Chao Jiang ◽  
Jianfeng Pan ◽  
Yuejin Zhu ◽  
Jianxing Li ◽  
Huilong Chen ◽  
...  
1985 ◽  
Vol 50 (12) ◽  
pp. 2697-2714
Author(s):  
Arnošt Kimla ◽  
Jiří Míčka

The formulation and solution of a boundary value problem is presented, describing the influence of the free convective diffusion on the forced one to a sphere for a wide range of Rayleigh, Ra, and Peclet, Pe, numbers. It is assumed that both the free and forced convection are oriented in the same sense. Numerical results obtained by the method of finite differences were approximated by an empirical formula based on an analytically derived asymptotic expansion for Pe → ∞. The concentration gradient at the surface and the total diffusion current calculated from the empirical formula agree with those obtained from the numerical solution within the limits of the estimated errors.


2021 ◽  
Vol 21 (2) ◽  
pp. 916-925
Author(s):  
SuKyung Jeon ◽  
Carissa H. Li ◽  
Daniel R. Talham

Molecules ◽  
2018 ◽  
Vol 23 (12) ◽  
pp. 3355 ◽  
Author(s):  
Wanyoung Lim ◽  
Sungsu Park

Three-dimensional (3D) cell culture is considered more clinically relevant in mimicking the structural and physiological conditions of tumors in vivo compared to two-dimensional cell cultures. In recent years, high-throughput screening (HTS) in 3D cell arrays has been extensively used for drug discovery because of its usability and applicability. Herein, we developed a microfluidic spheroid culture device (μFSCD) with a concentration gradient generator (CGG) that enabled cells to form spheroids and grow in the presence of cancer drug gradients. The device is composed of concave microwells with several serpentine micro-channels which generate a concentration gradient. Once the colon cancer cells (HCT116) formed a single spheroid (approximately 120 μm in diameter) in each microwell, spheroids were perfused in the presence of the cancer drug gradient irinotecan for three days. The number of spheroids, roundness, and cell viability, were inversely proportional to the drug concentration. These results suggest that the μFSCD with a CGG has the potential to become an HTS platform for screening the efficacy of cancer drugs.


CrystEngComm ◽  
2021 ◽  
Vol 23 (11) ◽  
pp. 2215-2221
Author(s):  
Emma Dennis ◽  
Soumya Kundu ◽  
Deepak Thrithamarassery Gangadharan ◽  
Jingjun Huang ◽  
Victor M. Burlakov ◽  
...  

Well-oriented PbBr2 microwires with a length-to-width ratio of up to 5000 were grown using a concentration gradient in co-crystallization with perovskite. Planar-integrated microwires showed a response to X-ray photons.


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