scholarly journals Fostering real-time climate adaptation: Analyzing past, current, and forecast temperature to understand the dynamic risk to Hawaiian honeycreepers from avian malaria

2020 ◽  
Vol 23 ◽  
pp. e01069
Author(s):  
Lucas Berio Fortini ◽  
Lauren R. Kaiser ◽  
Dennis A. LaPointe
2021 ◽  
Author(s):  
Kay Debby Mann ◽  
Norm Good ◽  
Farhad Fatehi ◽  
Sankalp Khanna ◽  
Victoria Campbell ◽  
...  

BACKGROUND Early warning tools identify patients at risk of deterioration in hospitals. Electronic medical records in hospitals offer real-time data, and the opportunity to automate early warning tools and provide real-time, dynamic risk estimates. OBJECTIVE This review describes published studies on the development, validation and implementation of tools for prediction of patient deterioration in hospital general wards. METHODS An electronic database search of peer-reviewed journal papers 2008-2020 identified studies reporting the use of tools and algorithms for predicting patient deterioration - defined by unplanned transfer to intensive care unit (ICU), cardiac arrest, or death. Studies conducted solely in ICUs, emergency departments or on single diagnosis patient groups were excluded. RESULTS Forty-five publications, eligible for inclusion, were heterogeneous in design, setting and outcome measures. Most papers were retrospective studies utilizing cohort data to develop, validate or statistically evaluate prediction tools. Tools consisted of early warning, screening or scoring systems based on physiologic data, as well as more complex algorithms developed to better represent real-time, deal with complexities of longitudinal data and warn of deterioration risk earlier. Only a few studies detailed the results of implementation of the deterioration warning tools. CONCLUSIONS Despite relative progress on the development of algorithms to predict patient deterioration, the literature has not shown that the deployment or implementation of such algorithms is reproducibly associated with improvement of patient outcomes. Further work is needed to realise the potential of automated predictions and updating dynamic risk estimates as part of an operational early warning system for inpatient deterioration.


2016 ◽  
Author(s):  
Andrew Hartigan ◽  
Darryl Thrasher ◽  
Robin Adlam

Author(s):  
Nicola Paltrinieri ◽  
Gabriele Landucci ◽  
Pierluigi Salvo Rossi

Recent major accidents in the offshore oil and gas (O&G) industry have showed inadequate assessment of system risk and demonstrated the need to improve risk analysis. While direct causes often differ, the failure to update risk evaluation on the basis of system changes/modifications has been a recurring problem. Risk is traditionally defined as a measure of the accident likelihood and the magnitude of loss, usually assessed as damage to people, to the environment, and/or economic loss. Recent revisions of such definition include also aspects of uncertainty. However, Quantitative Risk Assessment (QRA) in the offshore O&G industry is based on consolidated procedures and methods, where periodic evaluation and update of risk is not commonly carried out. Several methodologies were recently developed for dynamic risk analysis of the offshore O&G industry. Dynamic fault trees, Markov chain models for the life-cycle analysis, and Weibull failure analysis may be used for dynamic frequency evaluation and risk assessment update. Moreover, dynamic risk assessment methods were developed in order to evaluate the risk by updating initial failure probabilities of events (causes) and safety barriers as new information are made available. However, the mentioned techniques are not widely applied in the common O&G offshore practice due to several reasons, among which their complexity has a primary role. More intuitive approaches focusing on a selected number of critical factors have also been suggested, such as the Risk Barometer or the TEC2O. Such techniques are based on the evaluation of technical, operational and organizational factors. The methodology allows supporting periodic update of QRA by collecting and aggregating a set of indicators. However, their effectiveness relies on continuous monitoring activity and realtime data capturing. For this reason, this contribution focuses on the coupling of such methods with sensors of different nature located in or around and offshore O&G system. The inheritance from the Centre for Integrated Operations in the Petroleum Industries represents the basis of such study. Such approach may be beneficial for several cases in which (quasi) real-time risk evaluation may support critical operations. Two representative cases have been described: i) erosion and corrosion issues due to sand production; and ii) oil production in environmental sensitive areas. In both the cases, dynamic risk analysis may employ real-time data provided by sand, corrosion and leak detectors. A simulation of dynamic risk analysis has demonstrated how the variation of such data can affect the overall risk picture. In fact, this risk assessment approach has not only the capability to continuously iterate and outline improved system risk pictures, but it can also compare its results with sensor-measured data and allow for calibration. This can potentially guarantee progressive improvement of the method reliability for appropriate support to safety-critical decisions.


Parasitology ◽  
2017 ◽  
Vol 144 (13) ◽  
pp. 1743-1751 ◽  
Author(s):  
D. C. SIJBRANDA ◽  
B. D. GARTRELL ◽  
Z. L. GRANGE ◽  
L. HOWE

SUMMARYAvian malaria, caused by Plasmodium spp., is an emerging disease in New Zealand (NZ). To detect Plasmodium spp. infection and quantify parasite load in NZ birds, a real-time polymerase chain reaction (PCR) (qPCR) protocol was used and compared with a nested PCR (nPCR) assay. A total of 202 blood samples from 14 bird species with known nPCR results were tested. The qPCR prevalences for introduced, native and endemic species groups were 70, 11 and 21%, respectively, with a sensitivity and specificity of 96·7 and 98%, respectively, for the qPCR, while a sensitivity and specificity of 80·9 and 85·4% were determined for the nPCR. The qPCR appeared to be more sensitive in detecting lower levels of parasitaemia. The mean parasite load was significantly higher in introduced bird species (2245 parasites per 10 000 erythrocytes) compared with endemic species (31·5 parasites per 10 000 erythrocytes). In NZ robins (Petroica longipes), a significantly lower packed cell volume was found in birds that were positive for Plasmodium spp. compared with birds that were negative. Our data suggest that introduced bird species, such as blackbirds (Turdus merula), have a higher tolerance for circulating parasite stages of Plasmodium spp., indicating that introduced species are an important reservoir of avian malaria due to a high infection prevalence and parasite load.


2021 ◽  
Vol 12 ◽  
Author(s):  
John A. Donaghy ◽  
Michelle D. Danyluk ◽  
Tom Ross ◽  
Bobby Krishna ◽  
Jeff Farber

Foodborne pathogens are a major contributor to foodborne illness worldwide. The adaptation of a more quantitative risk-based approach, with metrics such as Food safety Objectives (FSO) and Performance Objectives (PO) necessitates quantitative inputs from all stages of the food value chain. The potential exists for utilization of big data, generated through digital transformational technologies, as inputs to a dynamic risk management concept for food safety microbiology. The industrial revolution in Internet of Things (IoT) will leverage data inputs from precision agriculture, connected factories/logistics, precision healthcare, and precision food safety, to improve the dynamism of microbial risk management. Furthermore, interconnectivity of public health databases, social media, and e-commerce tools as well as technologies such as blockchain will enhance traceability for retrospective and real-time management of foodborne cases. Despite the enormous potential of data volume and velocity, some challenges remain, including data ownership, interoperability, and accessibility. This paper gives insight to the prospective use of big data for dynamic risk management from a microbiological safety perspective in the context of the International Commission on Microbiological Specifications for Foods (ICMSF) conceptual equation, and describes examples of how a dynamic risk management system (DRMS) could be used in real-time to identify hazards and control Shiga toxin-producing Escherichia coli risks related to leafy greens.


2019 ◽  
Vol 9 (21) ◽  
pp. 4547 ◽  
Author(s):  
Mario Vega-Barbas ◽  
Víctor A. Villagrá ◽  
Fernando Monje ◽  
Raúl Riesco ◽  
Xavier Larriva-Novo ◽  
...  

With the increasing complexity of cyberthreats, it is necessary to have tools to understand the changing context in real-time. This document will present architecture and a prototype designed to model the risk of administrative domains, exemplifying the case of a country in real-time, specifically, Spain. In order to carry out this task, a modeling of the assets and threats detected by various sources of information has been carried out. All this information is stored as knowledge making use of ontologies, which enables the application of reasoning engines in order to infer new knowledge that can be used later in the following reasoning. This modeling and reasoning have been enriched with a dynamic system for managing the trust of the different sources of information and capabilities for increased reliability with the inclusion of additional threat intelligence information.


2013 ◽  
Vol 4 (2) ◽  
pp. 34-45
Author(s):  
Omar Gaci ◽  
Hervé Mathieu ◽  
Jean-Pierre Deutsch ◽  
Laurent Gomez

In this paper, a wireless sensor network is deployed to improve the security of goods, environment and persons along a supply chain manipulating chemicals in the European Union. Pallets are equipped with a RFID tag and a set of sensors that monitor in real-time the environment state. By defining and monitoring constraints that must satisfy pallet environments, a real-time risk assessment is proposed. Then, sensors send accident risks in case of unusual values to a centralized software. Supply chain actors responsible for goods are thus contacted and in parallel emergency services are contacted to plan and organize their interventions.


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