C-reactive protein gene variants associated with recurrent pregnancy loss independent of CRP serum levels: A case-control study

Gene ◽  
2015 ◽  
Vol 569 (1) ◽  
pp. 136-140 ◽  
Author(s):  
Salma K. Ahmed ◽  
Naeema Mahmood ◽  
Zainab H. Malalla ◽  
Fanar M. Alsobyani ◽  
Israa S. Al-Kiyumi ◽  
...  
2008 ◽  
Vol 197 (2) ◽  
pp. 931-936 ◽  
Author(s):  
Robert Y.L. Zee ◽  
Soren Germer ◽  
Abraham Thomas ◽  
Annaswammy Raji ◽  
Brian Rhees ◽  
...  

2020 ◽  
Vol 243 (6) ◽  
pp. 471-478
Author(s):  
Laura Gomes Nunes Melo ◽  
Paulo Henrique Morales ◽  
Karla Rezende Guerra Drummond ◽  
Deborah Conte Santos ◽  
Marcela Haas Pizarro ◽  
...  

<b><i>Introduction:</i></b> This study examined the relationship between proliferative diabetic retinopathy (PDR) and serum levels of C-reactive protein, VEGF, TNF-α, and IL-6 inflammatory biomarkers, related to the pathophysiology of diabetic retinopathy. <b><i>Methods:</i></b> This cross-sectional, case control study comprised 240 patients with type 1 diabetes (80 cases with PDR and 160 controls without diabetic retinopathy) who were matched for gender and duration of diabetes. <b><i>Results:</i></b> C-reactive protein was the only inflammatory biomarker that was positively related to PDR (OR 1.96; 95% CI 1.01–3.78, <i>p</i> = 0.0045). We also noted an association between high glycated hemoglobin levels, the use of angiotensin-converting enzyme inhibitor, low glomerular filtration rate, and PDR. <b><i>Conclusion:</i></b> Patients with higher levels of C-reactive protein are more likely to present with PDR. We did not find a link between serum levels of VEGF, TNF-α, or IL-6 and PDR. The function of inflammatory biomarkers in PDR must be addressed in further studies.


2020 ◽  
Vol 23 ◽  
pp. 100375 ◽  
Author(s):  
Qilin Li ◽  
Xiuli Ding ◽  
Geqing Xia ◽  
Heng-Gui Chen ◽  
Fenghua Chen ◽  
...  

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