PO174 Five Years Mortality Comparison Between Yoga Versus Non Yoga Group After ST Elevation Myocardial Infarction Managed With PCI According to LV Ejection Fraction

Global Heart ◽  
2018 ◽  
Vol 13 (4) ◽  
pp. 419
Author(s):  
N. Sen ◽  
A. Jain ◽  
S. Tanwar ◽  
R.K. Gokhroo
2021 ◽  
Author(s):  
◽  
Žanna Pičkure ◽  

It is well known that dysfunction of the right ventricle in ST segment elevation myocardial infarction causes such complications as rhythm disturbances, cardiogenic shock and others. Its presence is an independent prognostic indicator of all-cause mortality, cardiovascular mortality and development of heart failure. However, in clinical practice still too little attention is paid to the evaluation of the right ventricle function, despite the new echocardiographic methods available, which are capable of providing an accurate diagnostics of the right ventricle disfunction. The purpose of this work is to evaluate changes in the systolic function of the right ventricle in patients with proven acute ST elevation myocardial infarction by threedimensional echocardiography and myocardial strain techniques, and to select the most informative echocardiographic parameters for the size and function of the right ventricle for use in everyday practice. Based on the data gained during this study, the algorithm for the evaluation of the right ventricle function in patients with acute ST elevation myocardial infarction will be developed. A healthy individuals control group and a group of patients with ST elevation myocardial infarction were formed within the study. Each participant was examined according to standart echocardiography protocol. In each case new echocardiographic right venricle function evaluation methods also were applied – a three-dimensional echocardiography with following right ventricle reconstruction, volume and ejection fraction determination, as well as myocardial longitudinal strain measurements. Based on these methods, by comparing the data to the control group results, it was possible to etermine the pathology threshold for the right ventricular ejection fraction and longitudinal strain to detect right ventricle disfunction in the case of acute myocardial infarction. Three-dimensional echocardiography and evaluation of myocardial strain are new, relatively simple, sufficiently sensitive and specific methods for the diagnosis of right ventricular dysfunction in patients with ST elevation myocardial infarction. The methods are to be introduced for use in everyday clinical practice along with the standard ehocardiography parameters, which also change in ST elevation myocardial infarction: fractional area change, tricuspid annular plane systolic excursion, and visual evaluation of segmental systolic function of the right ventricle. Among new parameters ejection fraction of the right ventricle and right ventricle free wall longitudinal strain have to be determined. When evaluating the right chamber, it should be remembered that its function deterioration can be observed in case of myocardial infarction of any localization.


Circulation ◽  
2020 ◽  
Vol 142 (Suppl_3) ◽  
Author(s):  
Marie Sophie L de Koning ◽  
B. D Westenbrink ◽  
Solmaz Assa ◽  
Dirk J van Veldhuisen ◽  
Robin P Dullaart ◽  
...  

Background: Circulating ketone bodies (KB) are increased in patients with heart failure, corresponding with increased utilization of KB as a cardiac fuel. Whether circulating KB are increased in patients presenting with ST-elevation myocardial infarction (STEMI) and whether this is associated with infarct size is unknown. Methods: KB were measured in 379 non-diabetic participants of the Glycometabolic Intervention as Adjunct to Primary Percutaneous Coronary Intervention in ST-Segment Elevation Myocardial Infarction (GIPS) III trial (Clinicaltrial.gov Identifier: NCT01217307). Non-fasting plasma concentrations of the KB beta-hydroxybutyrate, acetoacetate, acetone were measured at presentation, 24 hours and 4 months after STEMI presentation using nuclear magnetic resonance spectroscopy. Associations of circulating KB with myocardial infarct size and left ventricular ejection fraction (both detected with MRI at 4 months after STEMI) were determined using multivariable linear regression analyses. Results: Circulating KB were higher at baseline (total KB 520 [315-997](median [IQR], μmol/L), compared to 206 [174-246] at 24 hours and 166 [143-201] at 4 months ( P <0.001 for all)). KB at 24 hours were positively associated with enzymatic infarct size, HbA1C and beta-blocker use. KB at 24 hours were independently associated with MRI outcomes at 4 months. Higher KB was associated with larger myocardial infarct size (total KB: standardized β=0.17, 95%-confidence interval (CI) (0.04-0.31), P =0.012) and lower ejection fraction (standardized β=-0.15, 95%-CI (-0.29- -0.009), P =0.037). Conclusion: Circulating KB are increased in patients with STEMI and are independently associated with myocardial infarct size and left ventricular function after 4 months of follow-up. The increase in circulating KB may reflect maladaptive changes of myocardial metabolism during the acute phase.


2009 ◽  
Vol 20 (1) ◽  
pp. 9-14 ◽  
Author(s):  
Mark B. Nienhuis ◽  
Jan Paul Ottervanger ◽  
Jan-Henk E. Dambrink ◽  
Menko-Jan de Boer ◽  
Jan CA. Hoorntje ◽  
...  

2017 ◽  
Vol 6 (2) ◽  
pp. 27-31
Author(s):  
Chandra Mani Adhikari ◽  
Reeju Manandhar ◽  
Dipanker Prajapati ◽  
Murari Dhungana ◽  
Anish Hirachan ◽  
...  

Background and Aims: Acute ST elevation myocardial infarction (STEMI) is often present in old populations. STEMI in young has significantly increased in recent years. We aim to study the conventional risk factors, clinical presentation, management and outcome of Acute STEMI in young patients.Methods: Medical records of all the young patients (aged less than 45 years), who were admitted in our hospital with the diagnosis of Acute STEMI and treated in between 1st July 2015 to 30th June 2016, were retrospectively reviewed. Demographics, conventional risk factors, clinical presentation, management and outcome were recorded.Results: There were total 1211 patients admitted for Acute STEMI, among them, 132(10.9%) were young patients, age ranged from 24 to 45 years with mean age 39.1±4.8 years, with 110 males. Anterior wall MI 50(37.8%) was the most common MI. Symptom onset to arrival to hospital ranged from 1 hour to 144 hours with mean of 19.4±2.4hours. Primary PCI was the mode of reperfusion in 59(44.6%) patients; thrombolysis was done in 19(14.3%) patients. The most common conventional risk factor was tobacco consumption; present in 91(68.9%) patients. Tobacco consumption was the only conventional risk factors in 27(20.4%) patients. There were four (4%) in-hospital mortality. Among the discharged patients all patients received Aspirin, Clopidogrel and Statin. Betablocker and Angiotensin converting enzyme inhibitor/Angiotensin receptor blocker were prescribed in 99(75%) and 96 (72.7%) patients respectively. Mean left ventricular ejection fraction was 45.5±8.6%, with 99(77.3%) having Ejection Fraction ≥40%.Conclusions: Acute STEMI in young was common in male. Tobacco consumption was significant riskfactor. Acute STEMI in young has good prognosis.Journal of Advances in Internal Medicine 2017;06(02):27-31.


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