Changes in anterior segment parameters and presence of dry eye disease in patients with acromegaly: A Sirius topography study combined with meibography

2021 ◽  
pp. 101424
Author(s):  
Deniz Kilic ◽  
Berkay Akmaz ◽  
Fahrettin Akay ◽  
Yusuf Ziya Guven ◽  
Guzide Gonca Oruk
Keyword(s):  
Dry Eye ◽  
Anterior Segment ◽  
Dry Eye Disease ◽  
Eye Disease ◽  
Anterior Segment Parameters

scholarly journals Tear evaluation by anterior segment OCT in dry eye disease

2021 ◽  
Vol 65 (1) ◽  
pp. 25-30
Author(s):  
Diana Mădălina Popovici ◽  
Ana Banc
Keyword(s):  
Dry Eye ◽  
Anterior Segment ◽  
Dry Eye Disease ◽  
Eye Disease ◽  
Anterior Segment Oct

scholarly journals Ocular Surface Changes Associated with Ophthalmic Surgery

2021 ◽  
Vol 10 (8) ◽  
pp. 1642
Author(s):  
Lina Mikalauskiene ◽  
Andrzej Grzybowski ◽  
Reda Zemaitiene
Keyword(s):  
Dry Eye ◽  
Ocular Surface ◽  
Anterior Segment ◽  
Dry Eye Disease ◽  
Postoperative Treatment ◽  
Eye Disease ◽  
Ophthalmic Surgery ◽  
Patient’S Satisfaction ◽  
The Impact ◽  
Anterior Segment Surgery

Dry eye disease causes ocular discomfort and visual disturbances. Older adults are at a higher risk of developing dry eye disease as well as needing for ophthalmic surgery. Anterior segment surgery may induce or worsen existing dry eye symptoms usually for a short-term period. Despite good visual outcomes, ocular surface dysfunction can significantly affect quality of life and, therefore, lower a patient’s satisfaction with ophthalmic surgery. Preoperative dry eye disease, factors during surgery and postoperative treatment may all contribute to ocular surface dysfunction and its severity. We reviewed relevant articles from 2010 through to 2021 using keywords “cataract surgery”, ”phacoemulsification”, ”refractive surgery”, ”trabeculectomy”, ”vitrectomy” in combination with ”ocular surface dysfunction”, “dry eye disease”, and analyzed studies on dry eye disease pathophysiology and the impact of anterior segment surgery on the ocular surface.

scholarly journals Botulinum Toxin A Injection for the Treatment of Intractable Dry Eye Disease

Medicina ◽  
2021 ◽  
Vol 57 (3) ◽  
pp. 247
Author(s):  
Eun Woo Choi ◽  
Dong Ju Yeom ◽  
Sun Young Jang
Keyword(s):  
Botulinum Toxin ◽  
Dry Eye ◽  
Botulinum Toxin A ◽  
Anterior Segment ◽  
Dry Eye Disease ◽  
Eye Disease ◽  
Medial Part ◽  
Test Results ◽  
Schirmer Test ◽  
Toxin A

Background and Objectives: To evaluate the clinical efficacy of periocular botulinum toxin A (BTA) injection in patients with intractable dry eye disease (DED). Materials and Methods: Medical records of patients with intractable DED who underwent periocular BTA injection from December 2019 to March 2020 were reviewed retrospectively. Patients were injected with 2.5 units of BTA in the medial part of the lower eyelids. The clinical data collected included age, sex, ocular surface disease index (OSDI) score, tear film break up time (TBUT), Schirmer test results, tear osmolarity (I-PEN), and tear meniscus height (TMH) measured by anterior segment optical coherence tomography. All subjective and objective data were collected before treatment and at 1 month after treatment. Results: Twenty-eight consecutive patients were eligible for chart review and analysis. Significant improvements in OSDI, tear osmolarity, and TMH were observed at 1 month after periorbital BTA injection. At the baseline and 1-month follow-up examinations, OSDI scores were 62.22 ± 21.30 and 47.98 ± 17.23, respectively (p < 0.001). TMH increased significantly after treatment (82.25 ± 40.50 at baseline vs. 138.02 ± 66.62 1-month after treatment; p < 0.001). Tear osmolarity using I-PEN showed a significant decrease after treatment (320.82 ± 24.66 at baseline vs. 302.75 ± 22.33 at 1 month after treatment; p < 0.001). No significant differences were found in TBUT or Schirmer test results before and after BTA injection. Conclusions: BTA injection into the medial part of the eyelid improves dry eye symptoms, the amount of tear retention, and tear osmolarity. Based on the objective parameters of the tear condition, this study supports the idea of BTA use as a potential treatment option for patients with intractable DED.

scholarly journals Advances in the Noninvasive Diagnosis of Dry Eye Disease

2021 ◽  
Vol 11 (21) ◽  
pp. 10384
Author(s):  
Luca Di Cello ◽  
Marco Pellegrini ◽  
Aldo Vagge ◽  
Massimiliano Borselli ◽  
Lorenzo Ferro Desideri ◽  
...  
Keyword(s):  
Dry Eye ◽  
Anterior Segment ◽  
Tear Film ◽  
Optical Quality ◽  
Dry Eye Disease ◽  
Diagnostic Tools ◽  
Eye Disease ◽  
Non Invasive ◽  
Integrated Devices

Dry eye disease (DED) is a multifactorial disease that represents one of the most common ophthalmologic conditions encountered in everyday clinical practice. Traditional diagnostic tests for DED, such as subjective questionnaires, tear film break-up time and the Schirmer test, are often associated with poor reproducibility and reliability, which make the diagnosis, follow-up, and management of the disease challenging. New advances in imaging technologies enable objective and reproducible measurements of DED parameters, thus making the diagnosis a multimodal imaging-based process. The aim of this review is to summarize all the current and emerging diagnostic tools available for the diagnosis and monitoring of DED, such as non-invasive tear breakup time, thermography, anterior segment optical coherence tomography, meibography, interferometry, in vivo confocal microscopy, and optical quality assessment. Although there is not a gold standard imaging technique, new multi-imaging-integrated devices are precious instruments to help clinicians to better cope with the diagnostic complexity of DED.

scholarly journals Objective Imaging Diagnostics for Dry Eye Disease

2020 ◽  
Vol 2020 ◽  
pp. 1-11 ◽  
Author(s):  
Sang Beom Han ◽  
Yu-Chi Liu ◽  
Karim Mohamed-Noriega ◽  
Louis Tong ◽  
Jodhbir S. Mehta
Keyword(s):  
Dry Eye ◽  
Clinical Symptoms ◽  
Imaging Techniques ◽  
Anterior Segment ◽  
Tear Film ◽  
Optical Quality ◽  
Dry Eye Disease ◽  
Eye Disease ◽  
Break Up

Traditional diagnostic tests for dry eye disease (DED), such as fluorescein tear film break-up time and the Schirmer test, are often associated with poor reproducibility and reliability, which make the diagnosis, follow-up, and management of the disease challenging. Advances in ocular imaging technology enables objective and reproducible measurement of changes in the ocular surface, tear film, and optical quality associated with DED. In this review, the authors will discuss the application of various imaging techniques, such as, noninvasive tear break-up time, anterior segment optical coherence tomography, in vivo confocal microscopy, meibography, interferometry, aberrometry, thermometry, and tear film imager in DED. Many studies have shown these devices to correlate with clinical symptoms and signs of DED, suggesting the potential of these imaging modalities as alternative tests for diagnosis and monitoring of the condition.

Sign in / Sign up

Export Citation Format

Share Document