scholarly journals Everolimus plus anastrozole for female adnexal tumor of probable Wolffian origin (FATWO) with STK11 mutation

2021 ◽  
pp. 100838
Author(s):  
Maria del Pilar Estevez-Diz ◽  
Renata Colombo Bonadio ◽  
Filomena Marino Carvalho ◽  
Jesus Paula Carvalho
Keyword(s):  
Adnexal Tumor

Case Report and Literature Review of Nodular Hidradenoma, a Rare Adnexal Tumor That Mimics Breast Carcinoma, in a 20-Year-Old Woman

2019 ◽  
Vol 50 (3) ◽  
pp. 320-325
Author(s):  
Vanya Jaitly ◽  
Richard Jahan-Tigh ◽  
Tatiana Belousova ◽  
Hui Zhu ◽  
Robert Brown ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Case Report ◽  
Breast Carcinoma ◽  
Literature Review ◽  
Sweat Glands ◽  
Rare Presentation ◽  
Adnexal Tumor ◽  
Nodular Hidradenoma ◽  
Growing Mass ◽  
Uncommon Tumor

Abstract Nodular hidradenoma is an uncommon cutaneous adnexal tumor arising from sweat glands. In the skin, it usually presents as a solitary dermal nodule; excision is curative in most cases. In rare instances, it may present as a breast mass and can mimic breast carcinoma clinically and radiologically, causing diagnostic dilemmas for the treating physician and pathologist. Herein, we discuss a case of nodular hidradenoma in a 20-year-old Hispanic woman as a rapidly growing mass in the breast that mimicked breast carcinoma. We discuss the rare presentation of this uncommon tumor and the differential diagnosis of this entity, as well as the results of our literature review on the topic.

Bullous Pilomatricoma: A Report of Clinical and Pathologic Findings and Review of Dermal Bullous Disorders

2001 ◽  
Vol 5 (5) ◽  
pp. 394-396 ◽  
Author(s):  
Gabriele E. Weichert ◽  
Kevin L. Bush ◽  
Richard I. Crawford
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Unusual Feature ◽  
Nous Rapportons ◽  
Pathological Feature ◽  
Pathological Features ◽  
Pathologic Findings ◽  
Hair Matrix ◽  
Adnexal Tumor ◽  
Vaisseaux Lymphatiques

Background: Pilomatricoma is a common benign adnexal tumor differentiating toward elements of the hair matrix and shaft. It typically presents as a solitary, deep, dermal nodule. We describe a case of a pilomatricoma with the unusual feature of a thick-walled dermal bulla overlying the tumor. Objective: We describe a case of bullous pilomatricoma and discuss the potential etiology of the bullous feature of the lesion. Methods: This article includes a case report and a literature review. Conclusions: Bullous pilomatricoma has rarely been described. A common pathological feature in this type of pilomatricoma is the presence of dilated lymphatics. Bullous morphea associated with dermal lymphatic dilation has also been described. In both bullous pilomatricoma and morphea, it is possible that individual pathological features of the lesion lead to obstruction and congestion of the dermal lymphatics thereby inducing enough dilation and edema to form a dermal bulla. Antécédents: Le pilomatrixome (épithéliome calcifiant de Malherbe) est une tumeur annexielle bénigne qui ressemble aux éléments de la matrice et de la tige pilaires. Il se manifeste typiquement par un nodule sous-cutané solitaire. Nous rapportons un cas de pilomatrixome présentant la caractéristique inhabituelle d'une bulle dermique à paroi épaisse située au-dessus de la tumeur. Objectifs: Décrire un cas de pilomatrixome bulleux et présenter l'étiologie potentielle d'une telle manifestation. Méthodes: Cet article comporte une étude de cas ainsi qu'une revue de la littérature. Conclusion: Le pilomatrixome bulleux a rarement été décrit. La dilatation des vaisseaux lymphatiques constitue une manifestation pathologique fréquente de cette forme de pilomatrixome. La morphée bulleuse a également été associée à une dilatation de vaisseaux lymphatiques. Il est possible que les caractéristiques pathologiques individuelles des lésions du pilomatrixome bulleux et de la morphée entraînent une obstruction et une congestion des vaisseaux lymphatiques, provoquant ainsi une dilatation et un œdème suffisamment importants pour former une bulle.

scholarly journals A Rare Cutaneous Adnexal Tumor: Malignant Proliferating Trichilemmal Tumor

2015 ◽  
Vol 2015 ◽  
pp. 1-4 ◽  
Author(s):  
Omer Alici ◽  
Musa Kemal Keles ◽  
Alper Kurt
Keyword(s):  
Differential Diagnosis ◽  
Elderly Women ◽  
Low Grade ◽  
Outer Root Sheath ◽  
Ki 67 ◽  
Morphological Findings ◽  
Root Sheath ◽  
Adnexal Tumor ◽  
Proliferating Trichilemmal Tumor ◽  
Malignant Proliferating Trichilemmal Tumor

Proliferating trichilemmal tumors (PTTs) are neoplasms derived from the outer root sheath of the hair follicle. These tumors, which commonly affect the scalp of elderly women, rarely demonstrate malignant transformation. Although invasion of the tumors into neighboring tissues and being accompanied with anaplasia and necrosis are accepted as findings of malignancy, histological features may not always be sufficient to identify these tumors. The clinical behavior of the tumor may be incompatible with its histological characteristics. Squamous-cell carcinoma should certainly be considered in differential diagnosis because of its similarity in morphological appearance with PTT. Immunostaining for CD34, P53, and Ki-67 is a useful adjuvant diagnostic method that can be used in differential diagnosis aside from morphological findings. In this study, we aimed to present the case of a 52-year-old female patient with clinicopathological features. We reported a low-grade malignant proliferating trichilemmal tumor in this patient and detected no relapse or metastasis in a 24-month period of follow-up.

Value of Intra-Adnexal and Extra-Adnexal Computed Tomographic Imaging Features Diagnosing Torsion of Adnexal Tumor

2009 ◽  
Vol 33 (6) ◽  
pp. 872-876 ◽  
Author(s):  
Jong Hwa Lee ◽  
Seong Bin Park ◽  
Sang Hoon Shin ◽  
Jong Chang Jang ◽  
Won Chan Lee ◽  
...  
Keyword(s):  
Tomographic Imaging ◽  
Imaging Features ◽  
Computed Tomographic ◽  
Adnexal Tumor ◽  
Computed Tomographic Imaging

scholarly journals Extra ocular sebaceous adenocarcinoma in HIV-positive patient - case report

2013 ◽  
Vol 88 (6 suppl 1) ◽  
pp. 19-22 ◽  
Author(s):  
Carla Kellen da Silva Menezes ◽  
Nathália Matos Gomes ◽  
Alex Panizza Jalkh ◽  
Emily dos Santos Franco ◽  
Thalita Gomes Martins
Keyword(s):  
Immune Deficiency ◽  
Immune Deficiency Syndrome ◽  
Acquired Immune Deficiency Syndrome ◽  
Deficiency Syndrome ◽  
Hiv Positive ◽  
Patient Case ◽  
Adnexal Tumor ◽  
The Face ◽  
Adnexal Tumors ◽  
Acquired Immune Deficiency

Sebaceous adenocarcinoma is a rare adnexal tumor that can affect the skin and is divided into ocular, a more common form and extra ocular, of a rarer occurrence. We report the case of a patient diagnosed with Acquired Immune Deficiency Syndrome (AIDS) who developed an extra ocular, bulky and fast-growing sebaceous adenocarcinoma on the face. The literature has suggested that transplanted patients and HIV-positive patients have an excess risk for developing adnexal tumors, including sebaceous adenocarcinoma.

scholarly journals Large Wolffian adnexal tumor of the ovary: A case report and literature review

2017 ◽  
Author(s):  
Ya‑Qiong Du ◽  
Shu‑Zheng Song ◽  
Xiao‑Chun Ni ◽  
Ju‑Gang Wu ◽  
Shou‑Lian Wang ◽  
...  
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Adnexal Tumor

scholarly journals Introduction of new tumor marker age score in clinical practice: Validity evaluation for differentiation benign from malignant adnexal masses

2012 ◽  
Vol 59 (3) ◽  
pp. 49-56
Author(s):  
Ivana Likic-Ladjevic ◽  
Milan Terzic ◽  
Nebojsa Ladjevic ◽  
Jelena Dotlic ◽  
Igor Pilic ◽  
...  
Keyword(s):  
Clinical Practice ◽  
Tumor Marker ◽  
Tumor Markers ◽  
Ca 125 ◽  
Benign Tumors ◽  
Tumor Type ◽  
Adnexal Masses ◽  
Combined Tumor ◽  
Adnexal Tumor ◽  
Adnexal Tumors

OBJECTIVE: The aim of the study was to examine several tumor markers and their correlation with pathohistological findings in patients with adnexal masses. METHODS: Study involved 139 patients, 84 of them with benign, 47 with malignant and 8 with borderline adnexal tumor. Levels of CA 125, CA 19-9, CEA and CA 15-3 were obtained preoperatively and assessed regarding the specific pathohistological diagnose and the patient?s age. Obtaining these results led us to divide the patient?s CA 125 levels with age and by doing that we have attained a new Tumor Marker Age score (TMA score). Results: Patients with malignant adnexal tumors had significantly higher levels of CEA (p<0.05), CA 125, CA 19-9 and CA 15-3 tumor markers (p<0.01), in comparison with patients with benign tumors. TMA score highly statistically correlate with the tumor type (benignant/malignant). CONCLUSIONS: With the increase of tumor marker levels and the patient?s age the malignant nature of adnexal tumors is more often. Results of our study highlight the importance of the use of combined tumor markers (at least CA-125 and CA 19-9) in women with adnexal masses. Those levels along with the patient?s age and new TMA score could preoperatively predict malignant nature of the tumor.

scholarly journals Paravaginal female adnexal tumor of probable Wolffian origin mimicking vaginal spindle cell epithelioma on biopsy

2019 ◽  
Vol 6 (1) ◽  
pp. 32
Author(s):  
Ryan Yu ◽  
Brigitte Courteau ◽  
Ryan Rebello ◽  
Alice Lytwyn ◽  
Monalisa Sur ◽  
...  
Keyword(s):  
Spindle Cell ◽  
Sampling Error ◽  
Broad Ligament ◽  
Proliferation Index ◽  
Unusual Site ◽  
Cell Architecture ◽  
Low Malignant Potential ◽  
Adnexal Tumor ◽  
Initial Biopsy ◽  
The Common

Female adnexal tumor of probable wolffian origin (FATWO) is a tumor of low malignant potential that arises predominantly in the broad ligament, mesosalpinx, and ovarian hilus. The rarity of FATWO increases its susceptibility to misdiagnosis as other tumors, especially when it occurs at an unusual site. We report a 29-year-old woman with a 7.2 cm left paravaginal FATWO that invaded into the vaginal lumen. The initial biopsy demonstrated features suggestive of vaginal spindle cell epithelioma, but with increased Ki67 proliferation index. Pathologists should be aware that the common sieve-like architecture of FATWO may not be apparent on small biopsies, which by sampling error may demonstrate predominantly the less common spindle cell architecture. Awareness of FATWO in the differential diagnosis of paravaginal tumors may help to avoid misinterpretation as vaginal spindle cell epithelioma, a previously unappreciated pitfall in the diagnosis of FATWO.

scholarly journals Cytological diagnosis of syringocystadenoma papilliferum a rare adnexal tumor

2015 ◽  
Vol 32 (2) ◽  
pp. 130 ◽  
Author(s):  
Sunita Bhargava ◽  
Namita Goyal ◽  
Isha Aggarwal
Keyword(s):  
Cytological Diagnosis ◽  
Syringocystadenoma Papilliferum ◽  
Adnexal Tumor
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