Aminocaproic acid for the management of bleeding in patients on extracorporeal membrane oxygenation: Four adult case reports and a review of the literature

Heart & Lung ◽  
2016 ◽  
Vol 45 (3) ◽  
pp. 232-236 ◽  
Author(s):  
Leo F. Buckley ◽  
David P. Reardon ◽  
Phillip C. Camp ◽  
Gerald L. Weinhouse ◽  
David A. Silver ◽  
...  
Keyword(s):  
Extracorporeal Membrane Oxygenation ◽  
Case Reports ◽  
Aminocaproic Acid ◽  
Review Of The Literature ◽  
Adult Case ◽  
Membrane Oxygenation

scholarly journals Use of Extracorporeal Membrane Oxygenation in Patients with Refractory Cardiac Arrest due to Severe Persistent Hypothermia: About 2 Case Reports and a Review of the Literature

2021 ◽  
Vol 2021 ◽  
pp. 1-5
Author(s):  
Rachid Attou ◽  
Sébastien Redant ◽  
Thierry Preseau ◽  
Kevin Mottart ◽  
Louis Chebli ◽  
...  
Keyword(s):  
Cardiac Arrest ◽  
Extracorporeal Membrane Oxygenation ◽  
Case Reports ◽  
Review Of The Literature ◽  
Neurological Sequelae ◽  
Membrane Oxygenation ◽  
Severe Hypothermia ◽  
Extracorporeal Cpr ◽  
Refractory Cardiac Arrest

We report the cases of two patients experiencing persistent severe hypothermia. They were 45 and 30 years old and had a witnessed cardiac arrest managed with mechanized cardiopulmonary resuscitation (CPR) for 4 and 2.5 hours, respectively. Extracorporeal membrane oxygenation was used in both patients who fully recovered without any neurological sequelae. These two cases illustrate the important role of extracorporeal CPR (eCPR) in persistent severe hypothermia leading to cardiac arrest.

scholarly journals Transportation of patients on extracorporeal membrane oxygenation: a tertiary medical center experience and systematic review of the literature

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Pedro Vitale Mendes ◽  
Cesar de Albuquerque Gallo ◽  
Bruno Adler Maccagnan Pinheiro Besen ◽  
Adriana Sayuri Hirota ◽  
Raquel de Oliveira Nardi ◽  
...  
Keyword(s):  
Systematic Review ◽  
Extracorporeal Membrane Oxygenation ◽  
Medical Center ◽  
Transportation Of Patients ◽  
Review Of The Literature ◽  
Membrane Oxygenation

Bleomycin-induced lung injury treated with venovenous extracorporeal membrane oxygenation (ECMO) and ultra-protective ventilator settings

2020 ◽  
Vol 13 (11) ◽  
pp. e236474
Author(s):  
Mazen Faris Odish ◽  
William Cameron McGuire ◽  
Patricia Thistlethwaite ◽  
Laura E Crotty Alexander
Keyword(s):  
Lung Injury ◽  
Extracorporeal Membrane Oxygenation ◽  
Case Reports ◽  
Rapid Onset ◽  
High Dose ◽  
Drug Induced ◽  
Membrane Oxygenation ◽  
Hypoxic Respiratory Failure ◽  
Venovenous Extracorporeal Membrane Oxygenation ◽  
Vv Ecmo

Bleomycin treats malignancies, such as germ cell tumours and Hodgkin lymphoma. While efficacious, it can cause severe drug-induced lung injury. We present a 42-year-old patient with stage IIB seminoma treated with radical orchiectomy followed by adjuvant chemotherapy with bleomycin, etoposide and cisplatin. His postbleomycin course was complicated by the rapid onset of hypoxic respiratory failure, progressing to acute respiratory distress syndrome and requiring venovenous extracorporeal membrane oxygenation (VV-ECMO) support. Although the patient was treated with high dose systemic steroids and ultra-protective ventilator strategies to minimise ventilator-induced lung injury while on VV-ECMO, his lung injury failed to improve. Care was withdrawn 29 days later. Lung autopsy revealed diffuse organising pneumonia. We found six case reports (including this one) of bleomycin-induced lung injury requiring VV-ECMO with a cumulative survival of 33% (2/6). While VV-ECMO may be used to bridge patients to recovery or lung transplant, the mortality is high.

scholarly journals Neurologically Devastating Intraparenchymal Hemorrhage in COVID-19 Patients on Extracorporeal Membrane Oxygenation: A Case Series

Neurosurgery ◽  
2020 ◽  
Vol 87 (2) ◽  
pp. E147-E151 ◽  
Author(s):  
Sabrina M Heman-Ackah ◽  
YouRong Sophie Su ◽  
Michael Spadola ◽  
Dmitriy Petrov ◽  
H Isaac Chen ◽  
...  
Keyword(s):  
Extracorporeal Membrane Oxygenation ◽  
Intracranial Hemorrhage ◽  
Case Reports ◽  
Case Series ◽  
Therapeutic Modality ◽  
Membrane Oxygenation ◽  
Resource Setting ◽  
Therapeutic Algorithms ◽  
Successful Recovery ◽  
Vv Ecmo

Abstract BACKGROUND AND IMPORTANCE Extracorporeal membrane oxygenation (ECMO) represents a life-saving therapy in cases of refractory hypoxia and has been utilized in patients suffering from the most severe forms of coronavirus disease 2019 (COVID-19). A strikingly high mortality rate of 94% was described in early reports of patients with COVID-19 transitioned to ECMO. Later case reports and series demonstrating successful recovery from COVID-19 after ECMO have revived interest in this therapeutic modality, including the recent approval of ECMO for COVID-19 patients by the Food and Drug Administration (FDA). Here, we present the first reports of devastating intracranial hemorrhage as a complication of veno-venous (VV) ECMO in two COVID-19 patients. CLINICAL PRESENTATION We performed a retrospective analysis of 2 cases of devastating intracranial hemorrhage in patients on VV-ECMO for the treatment of COVID-19. Collected data included clinical history, laboratory results, treatment, and review of all available imaging. Both patients demonstrated activated partial thromboplastin times (aPTT) within an appropriate therapeutic range. No risk factors that clearly predicted likelihood of this complication were identified. CONCLUSION Understanding the complications of ECMO in this cohort and developing therapeutic algorithms to aid in optimal patient selection will be critical in the limited resource setting experienced as a result of global pandemic. We propose the use of head computed tomography (CT) to identify devastating neurological complications as early as possible, aiding in the resource allocation of ECMO machines to the most appropriately selected patients.

Extracorporeal membrane oxygenation for Kawasaki disease: two case reports and the Extracorporeal Life Support Organization experience 1999–2015

Perfusion ◽  
2017 ◽  
Vol 32 (7) ◽  
pp. 609-612 ◽  
Author(s):  
Derek Best ◽  
Johnny Millar ◽  
Igor Kornilov ◽  
Yury Sinelnikov ◽  
Roberto Chiletti ◽  
...  
Keyword(s):  
Kawasaki Disease ◽  
Extracorporeal Membrane Oxygenation ◽  
Life Support ◽  
Extracorporeal Life Support ◽  
Case Reports ◽  
Membrane Oxygenation ◽  
Support Organization ◽  
Life Threatening ◽  
Acute Kawasaki Disease ◽  
Cardiac Manifestations

Kawasaki disease is usually a limited illness of early childhood. However, life-threatening cardiac manifestations can occur, either at acute presentation or as a consequence of coronary arterial involvement. We report the successful use of veno-arterial (VA) extracorporeal membrane oxygenation (ECMO) for cardiac support in two children with Kawasaki disease: one with acute Kawasaki disease shock syndrome, the other with complications of coronary arteritis and subsequent surgery. We also reviewed the reported experience in the ELSO database and available literature.

Sign in / Sign up

Export Citation Format

Share Document