ISDN2014_0055: Prenatal maternal stress from a natural disaster predicts hippocampus volumes in males at age 11: Project Ice Storm

2015 ◽  
Vol 47 (Part_A) ◽  
pp. 12-12 ◽  
Author(s):  
R. Dufoix ◽  
A. Charil ◽  
D.P. Laplante ◽  
T. Paus ◽  
J. Pruessner ◽  
...  
Keyword(s):  
Natural Disaster ◽  
Maternal Stress ◽  
Ice Storm ◽  
Prenatal Maternal Stress

Prenatal maternal stress from a natural disaster predicts dermatoglyphic asymmetry in humans

2009 ◽  
Vol 21 (2) ◽  
pp. 343-353 ◽  
Author(s):  
Suzanne King ◽  
Adham Mancini-Marïe ◽  
Alain Brunet ◽  
Elaine Walker ◽  
Michael J. Meaney ◽  
...  
Keyword(s):  
Natural Disaster ◽  
Maternal Stress ◽  
Significant Negative Correlation ◽  
Target Group ◽  
Ice Storm ◽  
Prenatal Maternal Stress ◽  
Lower Stress ◽  
The Face ◽  
Normal Controls ◽  
Objective Stress

AbstractDermatoglyphic asymmetry of fingertip ridge counts is more frequent in schizophrenia patients than normal controls, and may reflect disruptions in fetal development during Weeks 14–22 when fingerprints develop. However, there are no data in humans linking specific adverse events at specific times to dermatoglyphic asymmetries. Our objective was to determine whether prenatal exposure to a natural disaster (1998 Quebec ice storm) during Weeks 14–22 would result in increased dermatoglyphic asymmetry in children, and to determine the roles of maternal objective stress exposure, subjective stress reaction, and postdisaster cortisol. Ridge counts for homologous fingers were scored for 77 children (20 target exposed [Weeks 14–22] and 57 nontarget exposed [exposed during other gestation weeks]). Children in the target group had more than 0.50 SD greater asymmetry than the nontarget group. Within the target group, children whose mothers had high subjective ice storm stress had significantly greater asymmetry than those with lower stress mothers, and maternal postdisaster cortisol had a significant negative correlation with the children's dermatoglyphic asymmetry (r = −.56). Prenatal maternal stress during the period of fingerprint development results in greater dermatoglyphic asymmetry in their children, especially in the face of greater maternal distress.

scholarly journals Prenatal Maternal Stress from a Natural Disaster Alters Urinary Metabolomic Profiles in Project Ice Storm Participants

2018 ◽  
Vol 8 (1) ◽  
Author(s):  
Eric J. Paxman ◽  
Naveenjyote S. Boora ◽  
Douglas Kiss ◽  
David P. Laplante ◽  
Suzanne King ◽  
...  
Keyword(s):  
Natural Disaster ◽  
Maternal Stress ◽  
Ice Storm ◽  
Prenatal Maternal Stress

scholarly journals DNA Methylation Signatures Triggered by Prenatal Maternal Stress Exposure to a Natural Disaster: Project Ice Storm

PLoS ONE ◽  
2014 ◽  
Vol 9 (9) ◽  
pp. e107653 ◽  
Author(s):  
Lei Cao-Lei ◽  
Renaud Massart ◽  
Matthew J. Suderman ◽  
Ziv Machnes ◽  
Guillaume Elgbeili ◽  
...  
Keyword(s):  
Dna Methylation ◽  
Natural Disaster ◽  
Maternal Stress ◽  
Ice Storm ◽  
Prenatal Maternal Stress ◽  
Stress Exposure

scholarly journals Effect of Natural Disaster-Related Prenatal Maternal Stress on Child Development and Health: A Meta-Analytic Review

2021 ◽  
Vol 18 (16) ◽  
pp. 8332
Author(s):  
Sandra Lafortune ◽  
David P. Laplante ◽  
Guillaume Elgbeili ◽  
Xinyuan Li ◽  
Stéphanie Lebel ◽  
...  
Keyword(s):  
Child Development ◽  
Natural Disaster ◽  
Maternal Stress ◽  
Meta Analysis ◽  
Third Party ◽  
Ice Storm ◽  
Prenatal Maternal Stress ◽  
Analytic Review ◽  
Analytical Review ◽  
Meta Analyses

The evidence supporting the idea that natural disaster-related prenatal maternal stress (PNMS) influences the child’s development has been accumulating for several years. We conducted a meta-analytical review to quantify this effect on different spheres of child development: birth outcomes, cognitive, motor, physical, socio-emotional, and behavioral development. We systematically searched the literature for articles on this topic (2756 articles retrieved and 37 articles included in the systematic review), extracted the relevant data to calculate the effect sizes , and then performed a meta-analysis for each category of outcomes (30 articles included across the meta-analyses) and meta-regressions to determine the effect of some factors of interest on the association between PNMS and child development: type of PNMS (objective, psychological, cognitive, diet), type of natural disaster (ice storm, flood/cyclone), type of report (maternal, third-party observer, medical), timing of exposure (preconception exposure included or not) and child age at assessment (under 10 or 10 years and older). We found that PNMS significantly influences all spheres of child development. Higher PNMS levels were associated with longer gestational age, larger newborns, and higher BMI and adiposity levels, as well as worse cognitive, motor, socio-emotional, and behavioral outcomes.

scholarly journals Prenatal Maternal Stress Predicts Childhood Asthma in Girls: Project Ice Storm

2014 ◽  
Vol 2014 ◽  
pp. 1-10 ◽  
Author(s):  
Anne-Marie Turcotte-Tremblay ◽  
Robert Lim ◽  
David P. Laplante ◽  
Lester Kobzik ◽  
Alain Brunet ◽  
...  
Keyword(s):  
Life Events ◽  
Childhood Asthma ◽  
Maternal Stress ◽  
Small Study ◽  
Ice Storm ◽  
Prenatal Maternal Stress ◽  
Subjective Distress ◽  
Immune Functioning ◽  
Asthma Symptoms ◽  
Asthma Risk

Little is known about how prenatal maternal stress (PNMS) influences risks of asthma in humans. In this small study, we sought to determine whether disaster-related PNMS would predict asthma risk in children. In June 1998, we assessed severity of objective hardship and subjective distress in women pregnant during the January 1998 Quebec Ice Storm. Lifetime asthma symptoms, diagnoses, and corticosteroid utilization were assessed when the children were 12 years old (N=68). No effects of objective hardship or timing of the exposure were found. However, we found that, in girls only, higher levels of prenatal maternal subjective distress predicted greater lifetime risk of wheezing (OR=1.11; 90% CI = 1.01–1.23), doctor-diagnosed asthma (OR=1.09; 90% CI = 1.00–1.19), and lifetime utilization of corticosteroids (OR=1.12; 90% CI = 1.01–1.25). Other perinatal and current maternal life events were also associated with asthma outcomes. Findings suggest that stress during pregnancy opens a window for fetal programming of immune functioning. A sex-based approach may be useful to examine how prenatal and postnatal environments combine to program the immune system. This small study needs to be replicated with a larger, more representative sample.

Prenatal maternal stress predicts autism traits in 6½ year-old children: Project Ice Storm

2014 ◽  
Vol 219 (2) ◽  
pp. 353-360 ◽  
Author(s):  
Deborah J. Walder ◽  
David P. Laplante ◽  
Alexandra Sousa-Pires ◽  
Franz Veru ◽  
Alain Brunet ◽  
...  
Keyword(s):  
Maternal Stress ◽  
Ice Storm ◽  
Prenatal Maternal Stress ◽  
Autism Traits

Childhood body mass index at 5.5 years mediates the effect of prenatal maternal stress on daughters’ age at menarche: Project Ice Storm

2016 ◽  
Vol 8 (2) ◽  
pp. 168-177 ◽  
Author(s):  
A. Duchesne ◽  
A. Liu ◽  
S. L. Jones ◽  
D. P. Laplante ◽  
S. King
Keyword(s):  
Body Mass Index ◽  
Body Mass ◽  
Maternal Stress ◽  
Pubertal Timing ◽  
Self Report ◽  
Age At Menarche ◽  
Ice Storm ◽  
Prenatal Maternal Stress ◽  
Prospective Longitudinal ◽  
The Impact

Early pubertal timing is known to put women at greater risk for adverse physiological and psychological health outcomes. Of the factors that influence girls’ pubertal timing, stress experienced during childhood has been found to advance age at menarche (AAM). However, it is not known if stress experienced by mothers during or in the months before conception can be similarly associated with earlier pubertal timing. Prenatal maternal stress (PNMS) is associated with metabolic changes, such as increased childhood adiposity and risk of obesity, that have been associated with earlier menarchal age. Using a prospective longitudinal design, the present study tested whether PNMS induced by a natural disaster is either directly associated with earlier AAM, or whether there is an indirect association mediated through increased girls’ body mass index (BMI) during childhood. A total of 31 girls, whose mothers were exposed to the Quebec’s January 1998 ice storm during pregnancy were followed from 6 months to 5 1/2 to 5.5 years of age. Mother’s stress was measured within 6 months of the storm. BMI was measured at 5.5 years, and AAM was assessed through teen’s self-report at 13.5 and 15.5 years of age. Results revealed that greater BMI at 5.5 years mediated the effect of PNMS on decreasing AAM [B=−0.059, 95% confidence intervals (−0.18, −0.0035)]. The present study is the first to demonstrate that maternal experience of stressful conditions during pregnancy reduces AAM in the offspring through its effects on childhood BMI. Future research should consider the impact of AAM on other measures of reproductive ability.

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