scholarly journals Hand, foot and mouth disease in southern Vietnam during 2015–2018

2020 ◽  
Vol 101 ◽  
pp. 258
Author(s):  
N. Nguyen Thi Han ◽  
N. Le Nguyen Thanh ◽  
K. Truong Huu ◽  
H. Nguyen Thi Thu ◽  
V. Hoang Minh Tu ◽  
...  
Keyword(s):  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Southern Vietnam ◽  
Foot And Mouth

scholarly journals Use of Slaughterhouses as Sentinel Points for Genomic Surveillance of Foot-and-Mouth Disease Virus in Southern Vietnam

Viruses ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 2203
Author(s):  
Umanga Gunasekara ◽  
Miranda R. Bertram ◽  
Do H. Dung ◽  
Bui H. Hoang ◽  
Nguyen T. Phuong ◽  
...  
Keyword(s):  
Disease Virus ◽  
Foot And Mouth Disease ◽  
Principal Component ◽  
Mouth Disease ◽  
Serum Samples ◽  
Southern Vietnam ◽  
Serotype O ◽  
Healthy Cattle ◽  
Mouth Disease Virus ◽  
Foot And Mouth

The genetic diversity of foot-and-mouth disease virus (FMDV) poses a challenge to the successful control of the disease, and it is important to identify the emergence of different strains in endemic settings. The objective of this study was to evaluate the sampling of clinically healthy livestock at slaughterhouses as a strategy for genomic FMDV surveillance. Serum samples (n = 11,875) and oropharyngeal fluid (OPF) samples (n = 5045) were collected from clinically healthy cattle and buffalo on farms in eight provinces in southern and northern Vietnam (2015–2019) to characterize viral diversity. Outbreak sequences were collected between 2009 and 2019. In two slaughterhouses in southern Vietnam, 1200 serum and OPF samples were collected from clinically healthy cattle and buffalo (2017 to 2019) as a pilot study on the use of slaughterhouses as sentinel points in surveillance. FMDV VP1 sequences were analyzed using discriminant principal component analysis and time-scaled phylodynamic trees. Six of seven serotype-O and -A clusters circulating in southern Vietnam between 2017–2019 were detected at least once in slaughterhouses, sometimes pre-dating outbreak sequences associated with the same cluster by 4–6 months. Routine sampling at slaughterhouses may provide a timely and efficient strategy for genomic surveillance to identify circulating and emerging FMDV strains.

scholarly journals Enterovirus 71–associated Hand, Foot, and Mouth Disease, Southern Vietnam, 2011

2012 ◽  
Vol 18 (12) ◽  
pp. 2002-2005 ◽  
Author(s):  
Truong Huu Khanh ◽  
Saraswathy Sabanathan ◽  
Tran Tan Thanh ◽  
Le Phan Kim Thoa ◽  
Tang Chi Thuong ◽  
...  
Keyword(s):  
Enterovirus 71 ◽  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Southern Vietnam ◽  
Foot And Mouth

scholarly journals Epidemiologic and Virologic Investigation of Hand, Foot, and Mouth Disease, Southern Vietnam, 2005

2007 ◽  
Vol 13 (11) ◽  
pp. 1733-1741 ◽  
Author(s):  
Phan Van Tu ◽  
Nguyen Thi Thanh Thao ◽  
David Perera ◽  
Khanh Huu Truong ◽  
Nguyen Thi Kim Tien ◽  
...  
Keyword(s):  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Southern Vietnam ◽  
Foot And Mouth

scholarly journals First Genome Sequence of Foot-and-Mouth Disease Virus Serotype O Sublineage Ind2001e from Southern Vietnam

2019 ◽  
Vol 8 (10) ◽  
Author(s):  
Rachel M. Palinski ◽  
Miranda R. Bertram ◽  
Le T. Vu ◽  
Steven J. Pauszek ◽  
Ethan J. Hartwig ◽  
...  
Keyword(s):  
Disease Virus ◽  
Tissue Sample ◽  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Epithelial Tissue ◽  
Southern Vietnam ◽  
Serotype O ◽  
Mouth Disease Virus ◽  
Virus Serotype ◽  
Foot And Mouth

We report the polyprotein coding sequence of the newly defined Ind2001e sublineage of foot-and-mouth disease virus (FMDV) serotype O, isolated from a bovine epithelial tissue sample collected in 2017 in Kon Tum Province, Vietnam. This discovery updates FMDV diversity in Vietnam, has implications for FMDV epidemiology, and influences future vaccine selections.

scholarly journals Clinical and aetiological study of hand, foot and mouth disease in southern Vietnam, 2013–2015: Inpatients and outpatients

2019 ◽  
Vol 80 ◽  
pp. 1-9 ◽  
Author(s):  
Minh Tu Van Hoang ◽  
To Anh Nguyen ◽  
Tan Thanh Tran ◽  
Thi Ty Hang Vu ◽  
Nguyen Truc Nhu Le ◽  
...  
Keyword(s):  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Southern Vietnam ◽  
Foot And Mouth

scholarly journals Clinical, etiological and epidemiological investigations of hand, foot and mouth disease in southern Vietnam during 2015 – 2018

2020 ◽  
Vol 14 (8) ◽  
pp. e0008544
Author(s):  
Le Nguyen Thanh Nhan ◽  
Truong Huu Khanh ◽  
Nguyen Thi Thu Hong ◽  
Hoang Minh Tu Van ◽  
Le Nguyen Truc Nhu ◽  
...  
Keyword(s):  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Southern Vietnam ◽  
Foot And Mouth

scholarly journals A57 Clinical features and virology of hand, foot, and mouth disease in southern Vietnam from July 2013 to July 2015

2018 ◽  
Vol 4 (suppl_1) ◽  
Author(s):  
Hoang Minh Tu Van ◽  
Nguyen To Anh ◽  
Tran Tan Thanh ◽  
Vu Thi Ty Hang ◽  
Le Nguyen Truc Nhu ◽  
...  
Keyword(s):  
Clinical Features ◽  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Southern Vietnam ◽  
Foot And Mouth

scholarly journals A large epidemic of enterovirus 71 associated hand, foot and mouth disease in southern Vietnam, 2011

2012 ◽  
Vol 16 ◽  
pp. e274
Author(s):  
T.H. Khanh ◽  
S. Sabanathan ◽  
L.P.K. Thoa ◽  
T.C. Thuong ◽  
J. Farrar ◽  
...  
Keyword(s):  
Enterovirus 71 ◽  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Southern Vietnam ◽  
Foot And Mouth

Biophysical Measurement of Molecular Weight of Foot-and-Mouth Disease RNA Fragments

1974 ◽  
Vol 32 ◽  
pp. 262-263
Author(s):  
Sydney S. Breese ◽  
Howard L. Bachrach
Keyword(s):  
Chemical Properties ◽  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Distilled Water ◽  
Bovine Plasma ◽  
Mouth Disease Virus ◽  
Foot And Mouth ◽  
Carbon Coated ◽  
Rna Fragments ◽  
Physical And Chemical

Continuing studies on the physical and chemical properties of foot-and-mouth disease virus (FMDV) have included electron microscopy of RNA strands released when highly purified virus (1) was dialyzed against demlneralized distilled water. The RNA strands were dried on formvar-carbon coated electron microscope screens pretreated with 0.1% bovine plasma albumin in distilled water. At this low salt concentration the RNA strands were extended and were stained with 1% phosphotungstic acid. Random dispersions of strands were recorded on electron micrographs, enlarged to 30,000 or 40,000 X and the lengths measured with a map-measuring wheel. Figure 1 is a typical micrograph and Fig. 2 shows the distributions of strand lengths for the three major types of FMDV (A119 of 6/9/72; C3-Rezende of 1/5/73; and O1-Brugge of 8/24/73.

High resolution surface structure of foot-and-mouth disease virus

1978 ◽  
Vol 36 (2) ◽  
pp. 376-377
Author(s):  
S. S. Breese ◽  
H. L. Bachrach
Keyword(s):  
Electron Microscopy ◽  
High Resolution ◽  
Surface Structure ◽  
Disease Virus ◽  
Potassium Phosphate ◽  
Foot And Mouth Disease ◽  
Mouth Disease ◽  
Physical Measurements ◽  
Mouth Disease Virus ◽  
Foot And Mouth

Models for the structure of foot-and-mouth disease virus (FMDV) have been proposed from chemical and physical measurements (Brown, et al., 1970; Talbot and Brown, 1972; Strohmaier and Adam, 1976) and from rotational image-enhancement electron microscopy (Breese, et al., 1965). In this report we examine the surface structure of FMDV particles by high resolution electron microscopy and compare it with that of particles in which the outermost capsid protein VP3 (ca. 30, 000 daltons) has been split into smaller segments, two of which VP3a and VP3b have molecular weights of about 15, 000 daltons (Bachrach, et al., 1975).Highly purified and concentrated type A12, strain 119 FMDV (5 mg/ml) was prepared as previously described (Bachrach, et al., 1964) and stored at 4°C in 0. 2 M KC1-0. 5 M potassium phosphate buffer at pH 7. 5. For electron microscopy, 1. 0 ml samples of purified virus and trypsin-treated virus were dialyzed at 4°C against 0. 2 M NH4OAC at pH 7. 3, deposited onto carbonized formvar-coated copper screens and stained with phosphotungstic acid, pH 7. 3.

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