Parenting and childhood atopic dermatitis: A cross-sectional study of relationships between parenting behaviour, skin care management, and disease severity in young children

Abstract Better understanding of atopic dermatitis’ effect on quality of life could enhance current management and therapeutic strategies. Studies investigating factors related to the health-related quality of life (HRQOL) of children with atopic dermatitis and their caregivers are limited. This cross-sectional study included 559 children (<16 years) with atopic dermatitis and their caregivers. Disease severity was associated with infants’ HRQOL (moderate: IRR: 1.42, 95% CI 1.20–1.67; severe: IRR: 1.72, 95% CI 1.32–2.24). Age and disease severity were associated with children’s HRQOL (age: IRR: 0.99, 95% CI 0.98–1.00; moderate: IRR: 1.08, 95% CI 1.02–1.14). Quality of life subdomains itching/scratching, emotional distress and sleep disturbance were most reported and increased with higher disease severity. Both caregivers’ mental and physical health were negatively affected by children’s HRQOL (physical: IRR: 0.99, 95% CI 0.99–1.00; mental: IRR: 0.98, 95% CI 0.97–0.99). Sociodemographic characteristics (gender, ethnicity, educational attainment of carers, number of children) did not demonstrate significance in children’s HRQOL model. In conclusion, current atopic dermatitis diagnostics and treatment have to be extended to the factors influencing both children’ as their caregivers’ quality of life and adapting management accordingly. Itching/scratching, emotional distress and sleep disturbance deserve attention. Sociodemographic characteristics in children’s HRQOL models also merit attention in further research.

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Methicillin-resistant Staphylococcus aureus colonization and disease severity in atopic dermatitis: A cross-sectional study from South India

Indian Journal of Dermatology Venereology and Leprology ◽

10.4103/0378-6323.132250 ◽

2014 ◽

Vol 80 (3) ◽

pp. 229 ◽

Cited By ~ 14

Author(s):

George Kurien ◽

ManjulaVelikkakathu Divakaran ◽

SadeepMelethil Sadanandan ◽

K Sobhanakumari ◽

A Sarin ◽

...

Keyword(s):

Staphylococcus Aureus ◽

Atopic Dermatitis ◽

Disease Severity ◽

South India ◽

Methicillin Resistant Staphylococcus Aureus ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Methicillin Resistant

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Childhood atopic dermatitis: A cross-sectional study of relationships between child and parent factors, atopic dermatitis management, and disease severity

International Journal of Nursing Studies ◽

10.1016/j.ijnurstu.2014.09.008 ◽

2015 ◽

Vol 52 (1) ◽

pp. 216-228 ◽

Cited By ~ 23

Author(s):

Amy E. Mitchell ◽

Jennifer A. Fraser ◽

Joanne Ramsbotham ◽

Alina Morawska ◽

Patsy Yates

Keyword(s):

Atopic Dermatitis ◽

Disease Severity ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Parent Factors

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Urinary melatonin levels in children with atopic dermatitis and healthy controls

Dermatology Reports ◽

10.4081/dr.2019.8064 ◽

2019 ◽

Author(s):

Dwi Ratna Adisty ◽

Iskandar Zulkarnain ◽

Diah Mira Indramaya

Keyword(s):

Atopic Dermatitis ◽

Disease Severity ◽

Outpatient Clinic ◽

Allergic Diseases ◽

Cross Sectional Study ◽

Enzyme Linked Immunosorbent Assay ◽

Healthy Controls ◽

Sectional Study ◽

Pediatric Dermatology ◽

Cross Sectional

Melatonin an important immunomodulatory molecule in allergic diseases. Melatonin also plays a role in several body systems including to regulate circadian rhythms because of its role to cause drowsiness. Research shows in the case of atopic dermatitis (AD) circadian production of melatonin is reduced compared to healthy controls. This study aimed to investigate the differences of urinary melatonin levels between children with AD and healthy controls, and its relationship with disease severity. A cross sectional study was conducted in pediatric dermatology division of our outpatient clinic. Severity of AD was determined by using the instruments Scoring Atopic Dermatitis (SCORAD). Urinary melatonin levels were measured by Enzyme-linked immunosorbent assay (ELISA). The urinary melatonin levels in AD group were not significantly lower than in healthy controls (P =0.98 P<0.05) but the means show lower levels of urinary melatonin levels in AD group (486.73 ± 292.13 pg/ml , 611.51 ± 280.45 pg/ml, respectively). There were no significant association between urinary melatonin levels and disease severity (P > 0.05) but there’s a tendency of decreased urinary melatonin with increased the severity of AD.

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Cow’s milk exposure and atopic dermatitis after six months of age

Paediatrica Indonesiana ◽

10.14238/pi56.6.2016.325-9 ◽

2017 ◽

Vol 56 (6) ◽

pp. 325

Author(s):

Surya Jayanti Kadek ◽

Dewi Kumara Wati Ketut ◽

Karyana Putu Gede

Keyword(s):

Atopic Dermatitis ◽

Maternal Diet ◽

Multiple Logistic Regression Analysis ◽

Cross Sectional Study ◽

Cow’S Milk ◽

Milk Formula ◽

Sectional Study ◽

Cross Sectional ◽

Cow's Milk ◽

Study Population

Background About 60% of individuals with atopic dermatitis (AD) develop their first manifestation during infancy. Cow’s milk (CM) exposure is considered to be a risk factor for AD.Objective To evaluate for an association between cow’s milk exposure and atopic dermatitis in infants > 6 months of age. Methods This cross-sectional study consisted of subjects from a previous study and new subjects recruited in order to meet the minimum required number of subjects. Our study population comprised 120 infants, born between 1 February and 30 November, 2012 in Sanglah Hospital, Denpasar. Subjects were divided into CM and non-CM groups and analyzed for their risk of AD. Subjects were included to CM group if they were fed with cow’s milk/formula and included to non-CM group if they were breastfeed exclusively in the first six months of life. Other possible risk factors were assessed by multivariate analysis. Results One hundred twenty subjects were enrolled and analyzed (59 in the CM and 61 in the non-CM groups). The prevalence of AD was 30%. Multiple logistic regression analysis revealed a significant association between CM exposure and AD, with odds ratio (OR) 2.37 (95%CI 1.036 to 5.420; P=0.04). In addition, maternal diet including eggs and/or cow’s milk during the breastfeeding period was significantly associated with AD in infants (OR 3.18; 95%CI 1.073 to 9.427; P=0.04).Conclusion Cow’s milk exposure is significantly associated with atopic dermatitis in infants > six months of age.

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