scholarly journals Radiation Therapy Demonstrates Persistent Overall Survival Benefit in Locally Advanced or Metastatic Anaplastic Thyroid Cancer

2018 ◽  
Vol 102 (3) ◽  
pp. e285-e286
Author(s):  
J. Ma ◽  
A. Bell ◽  
B.H. Lok ◽  
J.E. Leeman ◽  
E.S. Anderson ◽  
...  
Keyword(s):  
Overall Survival ◽  
Radiation Therapy ◽  
Thyroid Cancer ◽  
Survival Benefit ◽  
Locally Advanced ◽  
Anaplastic Thyroid Cancer ◽  
Overall Survival Benefit

Radiotherapy to demonstrate persistent overall survival benefit in locally advanced or metastatic anaplastic thyroid cancer.

2018 ◽  
Vol 36 (15_suppl) ◽  
pp. e18115-e18115 ◽  
Author(s):  
Jennifer Ma ◽  
Andrew C. Bell ◽  
Benjamin H. Lok ◽  
Jonathan Eric Leeman ◽  
Erik Steven Anderson ◽  
...  
Keyword(s):  
Overall Survival ◽  
Thyroid Cancer ◽  
Survival Benefit ◽  
Locally Advanced ◽  
Anaplastic Thyroid Cancer ◽  
Overall Survival Benefit

scholarly journals Poorly Differentiated and Anaplastic Thyroid Cancer: Insights into Genomics, Microenvironment and New Drugs

Cancers ◽  
2021 ◽  
Vol 13 (13) ◽  
pp. 3200
Author(s):  
Alessandro Prete ◽  
Antonio Matrone ◽  
Carla Gambale ◽  
Liborio Torregrossa ◽  
Elisa Minaldi ◽  
...  
Keyword(s):  
Overall Survival ◽  
Thyroid Cancer ◽  
Median Overall Survival ◽  
Clinical Problem ◽  
Anaplastic Thyroid Cancer ◽  
New Drugs ◽  
Poor Survival ◽  
Tumor Microenvironments ◽  
Genetic Features ◽  
Poorly Differentiated

PDTC and ATC present median overall survival of 6 years and 6 months, respectively. In spite of their rarity, patients with PDTC and ATC represent a significant clinical problem, because of their poor survival and the substantial inefficacy of classical therapies. We reviewed the newest findings about genetic features of PDTC and ATC, from mutations occurring in DNA to alterations in RNA. Therefore, we describe their tumor microenvironments (both immune and not-immune) and the interactions between tumor and neighboring cells. Finally, we recapitulate how this upcoming evidence are changing the treatment of PDTC and ATC.

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