Application of conventional and high-pressure extraction techniques for the isolation of bioactive compounds from the aerial part of hemp (Cannabis sativa L.) assortment Helena

Experimental studies have provided convincing evidence that food bioactive compounds (FBCs) have a positive biological impact on human health, exerting protective effects against non-communicable diseases (NCD) including cancer and cardiovascular (CVDs), metabolic, and neurodegenerative disorders (NDDs). These benefits have been associated with the presence of secondary metabolites, namely polyphenols, glucosinolates, carotenoids, terpenoids, alkaloids, saponins, vitamins, and fibres, among others, derived from their antioxidant, antiatherogenic, anti-inflammatory, antimicrobial, antithrombotic, cardioprotective, and vasodilator properties. Polyphenols as one of the most abundant classes of bioactive compounds present in plant-based foods emerge as a promising approach for the development of efficacious preventive agents against NCDs with reduced side effects. The aim of this review is to present comprehensive and deep insights into the potential of polyphenols, from their chemical structure classification and biosynthesis to preventive effects on NCDs, namely cancer, CVDs, and NDDS. The challenge of polyphenols bioavailability and bioaccessibility will be explored in addition to useful industrial and environmental applications. Advanced and emerging extraction techniques will be highlighted and the high-resolution analytical techniques used for FBCs characterization, identification, and quantification will be considered.

Download Full-text

Extraction of Phenolic Compounds and Terpenes from Cannabis sativa L. By-Products: From Conventional to Intensified Processes

Antioxidants ◽

10.3390/antiox10060942 ◽

2021 ◽

Vol 10 (6) ◽

pp. 942

Author(s):

Emilie Isidore ◽

Hamza Karim ◽

Irina Ioannou

Keyword(s):

Phenolic Compounds ◽

Cannabis Sativa ◽

Biological Activities ◽

Operating Conditions ◽

Extraction Techniques ◽

Ultrasound Assisted Extraction ◽

Assisted Extraction ◽

Whole Plant ◽

Conventional Solvent Extraction ◽

By Products

Cannabis sativa L. is a controversial crop due to its high tetrahydrocannabinol content varieties; however, the hemp varieties get an increased interest. This paper describes (i) the main categories of phenolic compounds (flavonoids, stilbenoids and lignans) and terpenes (monoterpenes and sesquiterpenes) from C. sativa by-products and their biological activities and (ii) the main extraction techniques for their recovery. It includes not only common techniques such as conventional solvent extraction, and hydrodistillation, but also intensification and emerging techniques such as ultrasound-assisted extraction or supercritical CO2 extraction. The effect of the operating conditions on the yield and composition of these categories of phenolic compounds and terpenes was discussed. A thorough investigation of innovative extraction techniques is indeed crucial for the extraction of phenolic compounds and terpenes from cannabis toward a sustainable industrial valorization of the whole plant.

Download Full-text

High-pressure-assisted infusion of bioactive compounds in apple slices

Innovative Food Science & Emerging Technologies ◽

10.1016/j.ifset.2015.11.010 ◽

2016 ◽

Vol 33 ◽

pp. 100-107 ◽

Cited By ~ 18

Author(s):

Jincy M. George ◽

T. Senthamizh Selvan ◽

Navin K. Rastogi

Keyword(s):

High Pressure ◽

Bioactive Compounds ◽

Apple Slices

Download Full-text