Magnetic-Silica Nanocomposites and the functionalized forms for Environment and Medical Applications: a Review

Author(s):  
Is Fatimah ◽  
Ganjar Fadillah ◽  
Gani Purwiandono ◽  
Imam Sahroni ◽  
Dyah Purwaningsih ◽  
...  
2008 ◽  
Vol 8 (4) ◽  
pp. 1797-1802
Author(s):  
Zhifei Wang ◽  
Yafei Guo ◽  
Song Li ◽  
Yueming Sun ◽  
Nongyue He

Magnetic silica nanocomposites (magnetic nanoparticles core coated by silica shell) have the wide promising applications in the biomedical field and usually been prepared based on the famous Stöber process. However, the flocculation of Fe3O4 nanoparticles easily occurs during the silica coating, which limits the amount of magnetic silica particles produced in the Stöber process. In this paper, PMMA/Fe3O4 nanoparticles were used in the Stöber process instead of the “nude” Fe3O4 nanoparticles. And coating Fe3O4 with PMMA polymer beforehand can prevent magnetic nanoparticles from the aggregation that usually comes from the increasing of ionic strength during the hydrolyzation of tetraethoxysilane (TEOS) by the steric hindrance. The results show that the critical concentration of magnetic nanoparticles can increase from 12 mg/L for “nude” Fe3O4 nanoparticles to 3 g/L for PMMA/Fe3O4 nanoparticles during the Stöber process. And before the deposition of silica shell, the surface of PMMA/Fe3O4 nanoparticles had to be further modified by hydrolyzing them in CH3OH/NH3˙H2O mixture solution, which provides the carboxyl groups on their surface to react further with the silanol groups of silicic acid.


2011 ◽  
Vol 21 (13) ◽  
pp. 2548-2555 ◽  
Author(s):  
Maria Ada Malvindi ◽  
Antonio Greco ◽  
Francesco Conversano ◽  
Albert Figuerola ◽  
Maurizio Corti ◽  
...  

1976 ◽  
Vol 15 (02) ◽  
pp. 69-74
Author(s):  
M. Goldberg ◽  
B. Doyon

This paper describes a general data base management package, devoted to medical applications. SARI is a user-oriented system, able to take into account applications very different by their nature, structure, size, operating procedures and general objectives, without any specific programming. It can be used in conversational mode by users with no previous knowledge of computers, such as physicians or medical clerks.As medical data are often personal data, the privacy problem is emphasized and a satisfactory solution implemented in SARI.The basic principles of the data base and program organization are described ; specific efforts have been made in order to increase compactness and to make maintenance easy.Several medical applications are now operational with SARI. The next steps will mainly consist in the implementation of highly sophisticated functions.


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