Leflunomide ameliorates experimental autoimmune myasthenia gravis by regulating humoral and cellular immune responses

2021 ◽  
Vol 93 ◽  
pp. 107434
Author(s):  
Huan Huang ◽  
Hao Ran ◽  
Xiaoxi Liu ◽  
Lu Yu ◽  
Li Qiu ◽  
...  
Keyword(s):  
Immune Responses ◽  
Myasthenia Gravis ◽  
Cellular Immune Responses ◽  
Experimental Autoimmune Myasthenia Gravis ◽  
Autoimmune Myasthenia ◽  
Cellular Immune ◽  
Experimental Autoimmune

scholarly journals Estrogen Enhances Susceptibility to Experimental Autoimmune Myasthenia Gravis by Promoting Type 1-Polarized Immune Responses

2005 ◽  
Vol 175 (8) ◽  
pp. 5050-5057 ◽  
Author(s):  
Laurent Delpy ◽  
Victorine Douin-Echinard ◽  
Lucile Garidou ◽  
Corinne Bruand ◽  
Abdelhadi Saoudi ◽  
...  
Keyword(s):  
Immune Responses ◽  
Myasthenia Gravis ◽  
Experimental Autoimmune Myasthenia Gravis ◽  
Autoimmune Myasthenia ◽  
Experimental Autoimmune

scholarly journals Advances in Research on the Relationship between Intestinal Flora and Myasthenia Gravis

2020 ◽  
Author(s):  
Xingxing Wu ◽  
Yong Xu ◽  
Qin Wang ◽  
Yuhui Wei ◽  
Md Rezaul Karim ◽  
...  
Keyword(s):  
Myasthenia Gravis ◽  
Intestinal Flora ◽  
Normal Function ◽  
Experimental Autoimmune Myasthenia Gravis ◽  
New Ideas ◽  
Autoimmune Myasthenia ◽  
Human Immune ◽  
Cellular Immune ◽  
The Relationship ◽  
Experimental Autoimmune

Human intestinal flora refers to a large and diverse microbial population present in the digestive tract of the human body, which plays a significant role in the establishment of human immune homeostasis and the normal function of the immune system. Myasthenia Gravis is an autoimmune disease of the neuromuscular junction, mainly involved in the anti-acetylcholine receptor antibody, cellular immune dependence, and complement1. At present, studies have found that the intestinal flora of Myasthenia Gravis is different from that of healthy people. Probiotic therapy has been shown effective in the experimental autoimmune Myasthenia Gravis animal models. This article reviews the relationship between intestinal flora and Myasthenia Gravis, to provide new ideas for further study of the pathogenesis and clinical treatment of Myasthenia Gravis.

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