Evaluation of the completeness of interventions reported in published randomized controlled trials in plastic surgery: A cross-sectional review protocol

In plastic and reconstructive surgery, innovation and creativity have been foremost, with science and evidence following. Unlike for a number of other specialties, the advances in plastic surgery have largely come from imagination, innovations, and trial and error, rather than from scientific trials. Somewhat more than for the rest of surgery, in plastics (where the art and craft of each particular surgeon counts immeasurably), randomized controlled trials of techniques have failed to be generated in the past, due to the difficulty of objectively assessing the success of surgery with an aesthetic-based nature. Consequently, evidence-based study of plastic surgery is a relatively new and developing field. This chapter focuses on the growing importance of evidence-based surgery in this specialty, showing that scientific trials are now being performed with increasing frequency.

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Physicians’ knowledge, attitude, practice and perceived barriers to subject recruitment for randomized controlled trials in ghana.

Clinical Research and Clinical Trials ◽

10.31579/2693-4779/045 ◽

2021 ◽

Vol 4 (1) ◽

pp. 01-11

Author(s):

Ubong U. Ekpene ◽

Mawuli Ametefe ◽

Patrick Bankah ◽

George Wepeba ◽

Harry Akoto ◽

...

Keyword(s):

Clinical Trials ◽

Randomized Controlled Trials ◽

Perceived Barriers ◽

Controlled Trials ◽

Cross Sectional ◽

Randomized Controlled ◽

Subject Recruitment ◽

Recruitment Practices ◽

The World ◽

Knowledge And Attitude

Objectives: This study assesses the knowledge, attitude, practice and perceived barriers to subject recruitment into randomized controlled trials, and determine strategies to maximize subject recruitment and retention. Methods: A cross sectional, quantitative survey of 73 physicians working in Ghana was conducted assessing their knowledge and attitude towards randomized controlled trials, subject recruitment practices, self-reported barriers to subject recruitment and strategies to enhance subject recruitment. Results: Responses from 73 Ghanaian physicians were analyzed. 23 (31.5%) respondents knew of ongoing clinical trials in their specialty in Ghana while 32 (43.8%) physicians knew about trials in their specialties in various places in the world. 23 (31.5%) physicians responded that they had referred patients for recruitment into clinical trials before. 49 (67.1%) respondents had never referred any patient for recruitment into clinical trials. Conclusion: Most Ghanaian doctors are unaware of ongoing trials in their specialty and thus do not refer patients for recruitment.

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The critical appraisal of randomized controlled trials published in an Indian journal to assess the quality of reporting: A retrospective, cross-sectional study

Perspectives in Clinical Research ◽

10.4103/picr.picr_169_19 ◽

2021 ◽

Vol 0 (0) ◽

pp. 0

Author(s):

SandeepKumar Gupta ◽

RaviKant Tiwari ◽

RajKumar Goel

Keyword(s):

Randomized Controlled Trials ◽

Critical Appraisal ◽

Cross Sectional Study ◽

Controlled Trials ◽

Sectional Study ◽

Quality Of Reporting ◽

Cross Sectional ◽

Randomized Controlled ◽

Indian Journal

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A Cross-Sectional Analysis of Spin in Randomized Controlled Trials

Journal of General Internal Medicine ◽

10.1007/s11606-017-4252-2 ◽

2018 ◽

Vol 33 (3) ◽

pp. 247-248 ◽

Cited By ~ 1

Author(s):

Alexandra Woodbridge ◽

Ann Abraham ◽

Rosa Ahn ◽

Susan Saba ◽

Deborah Korenstein ◽

...

Keyword(s):

Randomized Controlled Trials ◽

Controlled Trials ◽

Cross Sectional ◽

Randomized Controlled ◽

Cross Sectional Analysis ◽

Sectional Analysis

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Hydrogen sulfide (H2S) - therapeutic relevance in rehabilitation and balneotherapy Systematic literature review and meta-analysis based on the PRISMA paradig

Balneo and PRM Research Journal ◽

10.12680/balneo.2021.438 ◽

2021 ◽

Vol 12 (3) ◽

pp. 176-195

Author(s):

Constantin MUNTEANU ◽

Diana MUNTEANU ◽

Gelu ONOSE

Keyword(s):

Systematic Review ◽

Hydrogen Sulfide ◽

Randomized Controlled Trials ◽

Medical Rehabilitation ◽

Controlled Trials ◽

Second Phase ◽

Case Control Studies ◽

Cross Sectional ◽

Randomized Controlled ◽

Relevance Criterion

Background. An active molecule in sulfurous mineral - therapeutic waters and also in sapropelic mud is H2S, a hormetic gaseous molecule that can actively penetrate the skin. While high levels of H2S are extremely toxic, low levels are tolerated and have potential cytoprotective effects, with anti-inflammatory and antioxidant applications. Objective. This systematic review aims to rigorously select related articles and identify within their content the main possible uses of hydrogen sulfide from balneary sources and to explain its physiological mechanisms and therapeutic properties. Methods. To elaborate our systematic review, we have searched for relevant open access articles in 6 international databases: Cochrane , Elsevier , NCBI/PubMed , NCBI/PMC , PEDro , and ISI Web of Knowledge/Science , published from January 2016 until July 2021. The contextually quested keywords combinations/ syntaxes used are specified on this page. The eligible articles were analyzed in detail regarding pathologies addressed by hydrogen sulfide. All articles with any design (reviews, randomized controlled trials, non-randomized controlled trials, case-control studies, cross-sectional studies), if eligible according to the above-mentioned selection methodology, containing in the title the selected combinations, were included in the analysis. Articles were excluded in the second phase if they did not reach the relevance criterion. Results. Our search identified, first, 291 articles. After eliminating the duplicates and non-ISI articles, remained 121 papers. In the second phase, we applied a PEDro selection filter, resulting in 108 articles that passed the relevance criterion and were included in this systematic review. Conclusions. H2S biology and medical relevance are not fully understood and used adequately for sanogenic or medical purposes. More research is needed to fully understand the mechanisms and importance of this therapeutic gase. The link between balneotherapy and medical rehabilitation regarding the usage of hydrogen sulfide emphasises the unity for this medical speciality.

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The quality of reporting in randomized controlled trials of acupuncture for knee osteoarthritis: A cross-sectional survey

PLoS ONE ◽

10.1371/journal.pone.0195652 ◽

2018 ◽

Vol 13 (4) ◽

pp. e0195652 ◽

Cited By ~ 4

Author(s):

Pengli Jia ◽

Li Tang ◽

Jiajie Yu ◽

Jiali Liu ◽

Deying Kang ◽

...

Keyword(s):

Knee Osteoarthritis ◽

Randomized Controlled Trials ◽

Controlled Trials ◽

Cross Sectional Survey ◽

Quality Of Reporting ◽

Cross Sectional ◽

Randomized Controlled

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Completeness of reporting in abstracts of randomized controlled trials in subscription and open access journals: cross-sectional study

Trials ◽

10.1186/s13063-019-3781-x ◽

2019 ◽

Vol 20 (1) ◽

Author(s):

Iva Jerčić Martinić-Cezar ◽

Ana Marušić

Keyword(s):

Open Access ◽

Randomized Controlled Trials ◽

Randomized Study ◽

Median Number ◽

Controlled Trials ◽

Journal Articles ◽

Cross Sectional ◽

Randomized Controlled ◽

Open Access Journals ◽

Completeness Of Reporting

Abstract Background Open access (OA) journals are becoming a publication standard for health research, but it is not clear how they differ from traditional subscription journals in the quality of research reporting. We assessed the completeness of results reporting in abstracts of randomized controlled trials (RCTs) published in these journals. Methods We used the Consolidated Standards of Reporting Trials Checklist for Abstracts (CONSORT-A) to assess the completeness of reporting in abstracts of parallel-design RCTs published in subscription journals (n = 149; New England Journal of Medicine, Journal of the American Medical Association, Annals of Internal Medicine, and Lancet) and OA journals (n = 119; BioMedCentral series, PLoS journals) in 2016 and 2017. Results Abstracts in subscription journals completely reported 79% (95% confidence interval [CI], 77–81%) of 16 CONSORT-A items, compared with 65% (95% CI, 63–67%) of these items in abstracts from OA journals (P < 0.001, chi-square test). The median number of completely reported CONSORT-A items was 13 (95% CI, 12–13) in subscription journal articles and 11 (95% CI, 10–11) in OA journal articles. Subscription journal articles had significantly more complete reporting than OA journal articles for nine CONSORT-A items and did not differ in reporting for items trial design, outcome, randomization, blinding (masking), recruitment, and conclusions. OA journals were better than subscription journals in reporting randomized study design in the title. Conclusion Abstracts of randomized controlled trials published in subscription medical journals have greater completeness of reporting than abstracts published in OA journals. OA journals should take appropriate measures to ensure that published articles contain adequate detail to facilitate understanding and quality appraisal of research reports about RCTs.

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