A new proposed severity score for seborrheic dermatitis of the face: SEborrheic Dermatitis Area and Severity Index (SEDASI)

2017 ◽  
Vol 76 (6) ◽  
pp. AB18
Keyword(s):  
Severity Score ◽  
Seborrheic Dermatitis ◽  
Severity Index ◽  
The Face

scholarly journals The Split-Face Comparison of the Combined Er-YAG Laser and Hydroquinone 4% With Hydroquinone 4% Alone in the Treatment of Melasma in Iranian Patients: A Prospective, Interventional Case Study

2020 ◽  
Vol 11 (1) ◽  
pp. 70-73
Author(s):  
Nastaran Namazi ◽  
Aida Hesami ◽  
Yasaman Ketabi
Keyword(s):  
Yttrium Aluminum Garnet ◽  
Skin Pigmentation ◽  
Combined Treatment ◽  
Psychological Impact ◽  
Severity Index ◽  
Controversial Issues ◽  
Yag Laser ◽  
Common Skin ◽  
The Face

Introduction: Melasma is one of the most common skin pigmentation disorders, which mostly affects the facial skin and has a considerable psychological impact on the patients. Melasma management has been one of the controversial issues in dermatology. We aimed to compare the combined treatment of the Er: YAG (erbium: yttrium–aluminum–garnet) laser plus hydroquinone (HQ) 4% with HQ 4% alone in the treatment of melasma. Methods: Twenty-nine patients were treated with the combined Er: YAG laser and HQ 4% on one side of the face with HQ 4% alone on the other side. Three sessions of the laser rat 4-week intervals. The outcome was calculated using the Melasma Area Severity Index (MASI). Results: The side that received the combined treatment (laser + HQ 4%) showed a statistically significant reduction in MASI compared to the side treated with HQ 4% alone. Conclusion: Our study suggests the superiority of the combination of the Er: YAG laser and HQ 4% in the treatment of melasma compared to HQ 4% alone.

scholarly journals Efficacy of SEBCLAIRA® Cream for Moderate Seborrhoeic Dermatitis on The Face as An Adjuvant Therapy (Randomised Clinical Trial, Double Blind)

2018 ◽  
Vol 2 (2) ◽  
pp. 54-60
Author(s):  
Inda Astri Aryani ◽  
Yulia Farida Yahya ◽  
Nina Roiana ◽  
Radema A Pranata
Keyword(s):  
Clinical Trial ◽  
Analogue Scale ◽  
Calcineurin Inhibitor ◽  
Severity Index ◽  
Randomised Clinical Trial ◽  
Double Blind Study ◽  
Double Blind ◽  
Seborrhoeic Dermatitis ◽  
The Face ◽  
The Mean

Background: Seborrhoeic dermatitis (SD) is a chronic papulosquamous inflammatory disease which resistant to medical treatment. Various treatment such as topical corticosteroid, antifungal and calcineurin inhibitor has been widely practiced and gives varying results Objective: Our objective was to compare the efficacy of Sebclaira® and topical hydrocortisone 2,5% for management of moderate SD on the face Methods: A randomised clinical trial, controlled, double blind study was performed for four weeks. We assessed the efficacy and side effects of these topical treatment. The severity of SD was evaluated using Seborrhea Area Severity Index-Facial (SASI-F) score. The severity of pruritus was evaluated using Visual Analogue Scale. Demographic characteristics, baseline SASI-F and VAS were recorded in the medical record. Results: A 34 patients (14 males, 20 females) with moderate SD on the face completed the four weeks study. The mean of SASI T2 and VAS score of the Sebclaira® group was significantly lower than Hydrocortisone 2.5% group with p = 0.000 and p = 0.000 respectively. Tolerance between Sebclaira® and Hydrocortisone 2.5% showed insignificant results (p = 1.000) Conclusions: The longer application of Sebclaira® was significantly more effective to improve moderate SD

scholarly journals Introduction of a Radiologic Severity Index for the 2019 Novel Corona Virus (COVID-19)

2020 ◽  
Author(s):  
Mehrzad Lotfi ◽  
Sepideh Sefidbakht ◽  
Mohsen Moghadami ◽  
Pouya Iranpour ◽  
Yasaman Emami ◽  
...  
Keyword(s):  
Severity Score ◽  
Scoring System ◽  
Severe Disease ◽  
Severity Of Illness ◽  
Severity Index ◽  
P Value ◽  
Cross Sectional ◽  
Lung Abnormalities ◽  
Severe Group ◽  
Reverse Relationship

Abstract Background: Given the limited number of beds in intensive care units, establishing a system that can predict the outcome in COVID19 positive patients based on imaging plays an important role in using resources efficiently. Therefor this study was conducted to design an optimal scoring system related to the severity of COVID19 cases for distinguishing severe from non-severe patients. Materials and Methods: In this cross-sectional retrospective study, 82 patients with a definite diagnosis of COVID-19 infection, who had at least one chest CT scan in hospital course were enrolled.To assess the severity of pulmonary parenchymal involvement, we semi-quantitatively evaluated the extent and nature of abnormalities. The area of lung involvement was scored in three levels based on a 0-4 grading scale. Also, we established a 4-point scoring system for defining the nature of lung abnormalities. The two scores were multiplied by each other. A final radiologic severity score was determined after adding together the scores of all levels.Result: Of all cases, fifty-three (64.6%) were male with an average age of age 53.75. Among the patients in our study, 7 (8.5%) had severe disease and the mortality rate was 7.2%. The mean (±standard deviation) of the radiologic severity score was 34.3(±18.4) in the severe group and 11.3(±11.4) in the non-sever group. (P-value <0.05). Also, we found a significant reverse relationship between our severity score and O2 saturation (P-value <0.05).Conclusion: The radiologic severity score demonstrated a significant correlation with the patients' mortality and severity of illness in COVID-19 patients.

scholarly journals Skin Needling to Enhance Depigmenting Serum Penetration in the Treatment of Melasma

2011 ◽  
Vol 2011 ◽  
pp. 1-7 ◽  
Author(s):  
G. Fabbrocini ◽  
V. De Vita ◽  
N. Fardella ◽  
F. Pastore ◽  
M. C. Annunziata ◽  
...  
Keyword(s):  
Clinical Symptoms ◽  
Combined Treatment ◽  
Psychological Impact ◽  
Severity Index ◽  
Term Treatment ◽  
Long Term Treatment ◽  
Severity Index Score ◽  
The Face ◽  
Facial Area ◽  
Difficult Challenge

Melasma is a common hypermelanotic disorder affecting the facial area which has a considerable psychological impact on the patient. Managing melasma is a difficult challenge that requires long-term treatment with a number of topical agents, such as rucinol and sophora-alpha. Aims. We aim to compare the combined treatment of skin needling and depigmenting serum with that using depigmenting serum alone in the treatment of melasma, in order to evaluate the use of microneedles as a means to enhance the drug’s transdermal penetration. Methods. Twenty patients were treated with combined skin needling and depigmenting serum on one side of the face and with depigmenting serum alone on the other side. The outcome was evaluated periodically for up to two months using the Melasma Area Severity Index score and the Spectrocolorimeter X-Rite 968. Results. The side with combined treatment (skin needling + depigmenting serum) presented a statistically significant reduction in MASI score and luminosity index (L) levels compared to the side treated with depigmenting serum alone, and clinical symptoms were significantly improved. Conclusions. Our study suggests the potential use of combining skin needling with rucinol and sophora-alpha compounds to achieve better results in melasma treatment compared to rucinol and sophora-alpha alone.

scholarly journals Seborrheic dermatitis: comparative effectiveness of standard and intermittent external therapy

2020 ◽  
Vol 96 (6) ◽  
pp. 56-64
Author(s):  
Evgeny A. Vasiliev-Stupalsky
Keyword(s):  
Controlled Trial ◽  
Seborrheic Dermatitis ◽  
Clinical Manifestations ◽  
Treatment Compliance ◽  
Long Term Results ◽  
Intermittent Therapy ◽  
Zinc Pyrithione ◽  
Topical Corticosteroids ◽  
The Face

Background. The chronic and recurrent nature of seborrheic dermatitis, its wide prevalence and multifactorial etiopathogenesis require a comparison of the effectiveness of different treatment strategies. Aim. In a randomized controlled trial to evaluate the effectiveness of standard and intermittent therapy with topical corticosteroids and activated zinc pyrithione (Skin-cap cream) in reducing the severity of clinical manifestations, the duration of remission of the disease, and compliance with treatment. Methods. The effectiveness of external therapy in patients with seborrheic dermatitis of the face and scalp was studied. All the examined patients had at least two episodes of exacerbation per year. Doctor's prescription Mometasone furoate cream 0.1% 1 time/day externally for 14 days, activated zinc pyrithione (Skin-cap cream) 2 times/day externally for 14 days, further 1 time a day 2 times a week for 14 days. Results. There was a comparable clinical effectiveness of antiinflammatory therapy in the short term with more stable results of intermittent therapy with the use of (Skin-cap cream) in the long term. Conclusions. Usage of activated zinc pyrithione (Skin-cap cream) according to the intermittent scheme in the treatment of seborrheic dermatitis of the face with the transition to the scalp is associated with long-term results. Safety of medicine allows to use it pro re nata by patients, e.g., in case of increased stress levels, diet incompliance, with no risks of adverse events, specific to topical corticosteroids, those increases treatment compliance.

scholarly journals PROFIL DERMATITIS SEBOROIK DI POLIKLINIK KULIT DAN KELAMIN RSUP PROF. DR. R. D. KANDOU MANADO PERIODE JANUARI-DESEMBER 2012

e-CliniC ◽  
2015 ◽  
Vol 3 (1) ◽  
Author(s):  
Ranita O. Terroe ◽  
Marlyn G. Kapantow ◽  
Renate T. Kandou
Keyword(s):  
Skin Disease ◽  
Antifungal Agent ◽  
Seborrheic Dermatitis ◽  
Descriptive Study ◽  
Skin Lesions ◽  
Age Group ◽  
Sebaceous Glands ◽  
The Face ◽  
Combined Medication

Abstract: Seborrheic dermatitis (SD) is a chronic, recurrent skin disease in areas which are abundant in sebaceous glands, with a prevalence of 3-5% worldwide. Though its pathogenesis is still unknown, SD is related to sebum overproduction and the fungus Malassezia. SD can be suffered by all kinds of ages, most commonly found in men. The skin lesions found are erythematous, yellowish, oily squamas with uncircumscribed border. Pitiriasis sika, also known as dandruff, is a mild type of SD often suffered by people.This research is a retrospective descriptive study based on the number of cases, gender, age, location of lesion, and type of medication. Results shown that out of 134 seborrheic dermatitis cases (3,3%), this disease is often suffered by the age group 45-65 years old (55,2%) and male (67,2%), with most lesions located on the face (53,7%) and with combined medication of corticosteroid + antifungal agent (62,7%).Keywords: seborrheic dermatitisAbstrak: Dermatitis seboroik (DS) adalah penyakit kulit kronis berulang pada area yang memiliki banyak kelenjar sebasea, dengan prevalensi 3-5% di dunia. Patogenesis DS belum diketahui, namun DS memiliki hubungan terhadap produksi sebum yang berlebih dan adanya jamur Malassezia.DS dapat diderita oleh semua golongan umur, biasanya lebih sering diderita laki-laki.Kelainan kulit DS berwujud ritema dan skuama berminyak dan agak kekuningan dengan batas kurang tegas.Pitiriasis sika, atau ketombe, adalah jenis ringan DS yang paling sering diderita.Penelitian ini merupakan penelitian deskriptif retrospektif berdasarkan jumlah kasus, jenis kelamin, umur, lokasi lesi, dan jenis pengobatan.Hasil penelitian ini menunjukkan bahwa dari 134 kasus dermatitis seboroik (3,3%), penyakit ini sering terjadi pada kelompok umur 45-65 tahun (55,2%), jenis kelamin laki-laki (67,2%), lokasi lesi wajah (53,7%), dan pengobatan kombinasi topikal antara kortikosteroid + antijamur (62,7%).Kata kunci: dermatitis seboroik

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