The Urticaria Control Test as a Tool for Monitoring Chronic Idiopathic/Spontaneous Urticaria Treatment: Results From XTEND-CIU, a 48-Week, Randomized, Placebo-controlled Study

This research is a long-term follow-up of a previously published, controlled trial on the effectiveness of 3 stuttering treatments (intensive smooth speech, parenthome smooth speech, and intensive electromyography feedback) for children and adolescents, aged 11 to 18 years, who stutter. The previous controlled trial showed all 3 treatments to be effective compared to nontreatment after 12 months. This paper reports on the treatment effectiveness after an average of 4 years post-treatment. Results demonstrate that treatment gains were maintained in the long term, with rates of stuttering similar to the 1-year postoutcomes. There were no significant differences among the 3 treatments in long-term effectiveness. This controlled study substantiates the claim that the treatments investigated will more than likely have substantial long-term benefits for the fluency and personality of children and adolescents who stutter.

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Clinical effects with customized brackets and CAD/CAM technology: a prospective controlled study

Progress in Orthodontics ◽

10.1186/s40510-021-00386-0 ◽

2021 ◽

Vol 22 (1) ◽

Author(s):

Julia Hegele ◽

Lena Seitz ◽

Cora Claussen ◽

Uwe Baumert ◽

Hisham Sabbagh ◽

...

Keyword(s):

Treatment Planning ◽

Group Treatment ◽

Treatment Time ◽

Randomized Study ◽

Controlled Study ◽

Clinical Effects ◽

Treatment Results ◽

Overall Treatment Time ◽

Significant Difference ◽

Cad Cam

Abstract Objective Nowadays, CAD/CAM technologies enrich orthodontics in several ways. While they are commonly used for diagnoses and treatment planning, they can also be applied to create individualized bracket systems. The purpose of this prospective quasi-randomized study was to evaluate the clinical efficiency of a customized bracket system and its comparison with directly bonded conventional self-ligating bracket treatment. Materials and methods Altogether 38 patients were separated into two groups, treated either with direct bonded self-ligating brackets (Damon, Ormco, USA) or with indirect bonded customized CAD/CAM brackets (Insignia™, Ormco, USA). Overall treatment time, number of treatment appointments, number of lost or repositioned brackets, number of arch wires and wire bends, Little Irregularity Index, cephalometric analyses and ABO scores were compared. Superimpositions of the virtual set-ups and the treatment results of the CAD/CAM group were performed to evaluate the clinical realization of the treatment planning. Results No differences between both treatment groups were found concerning overall treatment time, number of appointments and number of archwire bends. Bonding failures occurred more often using the CAD/CAM system. Indirectly bonded brackets did not have to be repositioned as often as directly bonded brackets. Treatment results with both systems were similar concerning their effects on the reduction of ABO scores. The number of used archwires was higher in the CAD/CAM group. Treatment with both systems led to further proclination of the incisors. Proclination in the lower jaw was greater than proclination in the upper jaw, and there was a statistically significant difference between the two treatment systems. Comparing the treatment results with the virtual set-ups, mesial positions were met best, followed by vertical positions. Transversal positions showed the greatest discrepancies. Concerning angles, values of angulation showed greatest accordance to the virtual set-up, while values of inclinations showed greatest discrepancies. Conclusion In comparison with a direct bonded self-ligating bracket system the use of indirect bonded customized CAD/CAM brackets showed only minor influence on treatment efficiency and treatment outcomes. Transversal expansion, deep bite correction, expression of torque and anchorage loss remain challenges in the treatment with straight-wire appliances. Trial registration DRKS, DRKS00024350. Registered 15 February 2021, https://www.drks.de/drks_web/navigate.do?navigationId=trial.HTML&TRIAL_ID=DRKS00024350.

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Evidence for safety and efficacy of risedronate in men with osteoporosis over 4years of treatment: Results from the 2-year, open-label, extension study of a 2-year, randomized, double-blind, placebo-controlled study

Bone ◽

10.1016/j.bone.2012.06.016 ◽

2012 ◽

Vol 51 (3) ◽

pp. 383-388 ◽

Cited By ~ 17

Author(s):

Steven Boonen ◽

Roman S. Lorenc ◽

Dietrich Wenderoth ◽

Karen J. Stoner ◽

Rachelle Eusebio ◽

...

Keyword(s):

Extension Study ◽

Controlled Study ◽

Treatment Results ◽

Open Label ◽

Double Blind ◽

Safety And Efficacy ◽

Double Blind Placebo ◽

Open Label Extension

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Impotence: Prognosis (A Controlled Study)

The British Journal of Psychiatry ◽

10.1192/bjp.128.2.194 ◽

1976 ◽

Vol 128 (2) ◽

pp. 194-198 ◽

Cited By ~ 46

Author(s):

J. M. A. Ansari

Keyword(s):

Poor Prognosis ◽

Specific Treatment ◽

Controlled Study ◽

Physical Factors ◽

Not Given ◽

Treatment Results ◽

Physiological Factors ◽

Behaviour Modification ◽

Physical Trauma ◽

Erectile Impotence

SummarySixty-five patients primarily referred for erectile impotence were investigated and treated in a psychiatric out-patient department. Information was obtained from patients and wherever possible from their partners. Subjects were treated either with chemotherapy or with a modified form of Masters and Johnson's technique. A controlled group were not given any specific treatment. Results indicated that neither chemotherapy or behaviour modification (modified Masters and Johnson's technique) were in any way superior to no treatment. The prognosis was related to the clinical features of the subjects rather than to the form of treatment. Subjects in whom impotence was caused by a specific psychological or physical trauma showed a much better prognosis than those who had an insidious decline in sexual potency without any discernible psychological or physical factors. The decline in these latter subjects with a very poor prognosis was possibly due to inherent physiological factors.

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Prevelance and Causes of Facial Hyperpigmentation in Egypt: Dermoscopic and Histopathological Study

QJM ◽

10.1093/qjmed/hcaa046.012 ◽

2020 ◽

Vol 113 (Supplement_1) ◽

Author(s):

M A Abdallah ◽

M Y Sultan ◽

A H Abdallah

Keyword(s):

Histopathological Examination ◽

Final Diagnosis ◽

Controlled Study ◽

Histopathological Study ◽

Diverse Population ◽

University Hospitals ◽

Treatment Results ◽

Cross Sectional ◽

The Face ◽

Solar Lentigo

Abstract Background One of the most common dermatological complaints from patients with skin of color is dyspigmentation, particularly hyperpigmentation. The challenge for clinicians is to establish correct diagnoses along with successful treatments to meet the needs of the increasingly diverse population. Aim of the Work To identify the prevalence and the causes of facial hyperpigmented lesions in Egyptian people by using dermoscope and histopathological examination. Patients and Methods This study is a prospective cross-sectional non-controlled study that included 125 patients with facial hyperpigmentary lesions on the face. The patients were randomly recruited from the outpatient clinic of Dermatology at Ain Shams University Hospitals, during the period from July 2017 till December 2018. Results In our study, 67 patients (44%) had melasma; 25patient (16%) PIH and 23 (15%) patients showed freckles. In addition, SK was diagnosed in 10 patients (6%), phototoxicity in 4 patients (2.5%), 11(7.5%) patient was diagnosed with LPP, riehls melanosis was also diagnosed in 3 patients (2%), 2 patient presented with epidermal naevi (1.8%) and one patient presented with naevus of ota (0.5%) and one with solar lentigo (0.5%). Conclusion Dermoscopic examination can be dignostec in some diseases like SK and it can be helpful the determine the level of pigmentation and to expect the treatment results. And correlation between histopathology and dermoscopy can be helpful to reach the final diagnosis ant to determine the best treatment choice.

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